Projects funded by the NCN

Investigation of the mechanism of enhanced liposome delivery to tumors and its application for dual target immunotherapy

Call: OPUS 28 , Panel: NZ7

Principal investigator: dr hab. Tomasz Piotr Rygiel

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Neutrophil Dynamics: Unveiling Anti-Tumor and Therapy Efficacy with the TUmor Neutrophil Immunotherapy on Chip (TUNIC) m...

Call: SONATA 20 , Panel: NZ6

Principal investigator: dr Martin Nurmik

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Small molecule modulators of the tumor necrosis factor alpha signaling pathway for the inhibition of inflammatory proces...

Call: OPUS 27 , Panel: NZ7

Principal investigator: prof. Tadeusz Holak

Uniwersytet Gdański

Increasing sensitivity to immunotherapy in lung cancer via immunostimulation and modulation of tumor microenvironment

Call: SONATA BIS 13 , Panel: NZ5

Principal investigator: dr Urszula Oleksiewicz

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Spatial Determinants of Immunotherapy Resistance in Cancer

Call: WEAVE-UNISONO , Panel: NZ6

Principal investigator: dr Marcin Tabaka

Instytut Chemii Fizycznej Polskiej Akademii Nauk, Międzynarodowe Centrum Badań Oka

CO-TARGETING OF TUMOR MICROENVIRONMENT-MEDIATED ADAPTATION TO HYPOXIA RENDERS GLIOBLASTOMA MORE SUSCEPTIBLE TO ONCOLYTIC...

Call: OPUS 23 , Panel: NZ5

Principal investigator: dr hab. Agnieszka Marta Bronisz

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Depletion of the tumor microenvironment as a novel strategy potentiating the efficacy of immunotherapies.

Call: OPUS 23 , Panel: NZ6

Principal investigator: dr Małgorzata Agnieszka Bajor

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

The clinical significance of immunosuppression in ovarian cancer microenvironments

Call: PRELUDIUM 20 , Panel: NZ6

Principal investigator: dr Anna Maria Pawłowska-Łachut

Uniwersytet Medyczny w Lublinie

Single cell multi-omics in defining how specific oncogenic alterations shape the immune microenvironment and responses t...

Call: OPUS 20 , Panel: NZ4

Principal investigator: prof. Bożena Kamińska-Kaczmarek

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Comprehensive characterization of tumor immune contexture changes induced by cytotoxic agents in non-small cell lung can...

Call: PRELUDIUM BIS 2 , Panel: NZ5

Principal investigator: prof. Wojciech Maksymilian Fendler

Uniwersytet Medyczny w Łodzi

Modulation of immune cells activity in the tumor microenvironment by oligonucleotide therapeutics delivered by silk nano...

Call: OPUS 19 , Panel: NZ6

Principal investigator: prof. Hanna Dams-Kozłowska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Tyrosine-modified polyethylenimine polymers as a promising vectors for siRNA delivery in synergistic cancer immunotherap...

Call: PRELUDIUM 19 , Panel: NZ5

Principal investigator: Małgorzata Kubczak

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Analysis of the effectiveness of glioblastoma immunotherapy using gamma-delta T cells

Call: OPUS 18 , Panel: NZ6

Principal investigator: dr hab. Grzegorz Jacek Chodaczek

Wrocławskie Centrum Badań EIT+ Sp. z o.o.

Investigation on PD-L1 biology for precise shaping of anticancer adoptive therapies

Call: SONATA 15 , Panel: NZ6

Principal investigator: dr Agnieszka Graczyk-Jarzynka

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

STING protein activation combined with anti-vascular agent as a novel strategy for anticancer therapy

Call: OPUS 16 , Panel: NZ5

Principal investigator: dr hab. Ryszard Smolarczyk

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Modified tumor-derived exosomes as novel nanocarriers of anti-tumor molecules for the reprogramming of tumor microenviro...

Call: SONATA BIS 8 , Panel: NZ5

Principal investigator: dr Joanna Rossowska

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

The role of arginase-1 in antitumor efficacy of cancer immunotherapy using checkpoint inhibitors

Call: OPUS 12 , Panel: NZ6

Principal investigator: prof. Dominika Anna Nowis

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego