Projects funded by the NCN


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194 projects found matching your search criteria :

  1. MIST: Artificial intelligence-assisted design of experiments as a tool to streamline the development of siRNA-lipid nano...

    Call: OPUS 29 , Panel: NZ7

    Principal investigator: dr hab. Paulina Krystyna Skupin-Mrugalska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  2. Destabilization of neuronal morphology in chronic inflammation: molecular mechanisms and identification of potential the...

    Call: OPUS 29 , Panel: NZ5

    Principal investigator: prof. Jacek Ryszard Jaworski

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  3. Developing an AI algorithm for longitudinal tracking of post-treatment changes in brain metastases using a hybrid Uncert...

    Call: PRELUDIUM 24 , Panel: NZ7

    Principal investigator: Monika Żaneta Pytlarz

    Sano - Centrum Zindywidualizowanej Medycyny Obliczeniowej - Międzynarodowa Fundacja Badawcza

  4. Astrocytic Mitochondria in PACS2 Syndrome: Pathogenesis and Therapeutic Intervention

    Call: PRELUDIUM 24 , Panel: NZ5

    Principal investigator: Arkadiusz Franciszek Żbikowski

    Uniwersytet Medyczny w Białymstoku

  5. TP53 mutations drive alternative FGFR1 splicing - the study of consequences for cancer progression and therapeutic oppor...

    Call: PRELUDIUM 24 , Panel: NZ4

    Principal investigator: Weronika Wojtyś

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  6. The JAK/STAT pathway as a molecular contributor to the development of endometriosis: therapeutic potential of JAK inhibi...

    Call: PRELUDIUM 24 , Panel: NZ7

    Principal investigator: Aleksander Radosław Rycerz

    Uniwersytet Medyczny w Łodzi

  7. CTC-on-CAM: a platform for studying heterogeneity, epithelial-mesenchymal transition, and therapeutic sensitivity of cir...

    Call: OPUS 29 , Panel: NZ7

    Principal investigator: prof. Marek Arkadiusz Murias

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  8. Molecular Pathogenesis and Precision Antisense Oligonucleotide Therapy for BAG3-Related Myofibrillar Myopathy Type 6 Usi...

    Call: OPUS 29 , Panel: NZ2

    Principal investigator: dr Estera Elmira Rintz

    Uniwersytet Gdański

  9. Therapeutic evaluation of anti-fibrotic agents for thyroid eye disease (TED) in a preclinical mouse model

    Call: PRELUDIUM 24 , Panel: NZ6

    Principal investigator: Paweł Franciszek Tyrna

    CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

  10. Therapeutic potential of an FGF21 analogue in HFpEF: targeting cardiac, skeletal muscle, and cognitive function to impro...

    Call: PRELUDIUM 24 , Panel: NZ4

    Principal investigator: Maria Katarzyna Głowienka-Stodolak

    CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

  11. Targeted Degradation of the MLL Complex in Leukemia: A PROTAC-Based Therapeutic Strategy

    Call: SONATINA 9 , Panel: ST5

    Principal investigator: dr Natalia Anna Skrzypczak

    Fundacja Uniwersytetu im. Adama Mickiewicza

  12. Antibacterial molecules based on bacteriophage proteins and constant antibody fragments with therapeutic potential for t...

    Call: SONATA 20 , Panel: NZ7

    Principal investigator: dr Karolina Aleksandra Filik-Matyjaszczyk

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  13. Modulating Neuroplasticity with Psilocybin: Assesment Therapeutic Potential in Treating Fentanyl use disorder

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: dr hab. Ewa Taracha

    Instytut Psychiatrii i Neurologii

  14. Identifying early biomarkers and molecular targets for therapeutic intervention in right ventricular dysfunction

    Call: OPUS 28 , Panel: NZ5

    Principal investigator: prof. Przemysław Błyszczuk

    Uniwersytet Jagielloński

  15. Porous bioglass-alginate composite granules as the antibiotic delivery system with therapeutic and regenerative potentia...

    Call: SONATA 20 , Panel: NZ7

    Principal investigator: dr Adrian Szewczyk

    Gdański Uniwersytet Medyczny

  16. A triple agonist of glucagon, GLP-1, and GIP receptors as a novel therapeutic option for the treatment of heart failure ...

    Call: SONATA 20 , Panel: NZ5

    Principal investigator: dr Marta Katarzyna Oknińska

    CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

  17. Selective autophagy-mediated protein degradation as a potential therapeutic strategy for the treatment of inflammatory c...

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: dr hab. Monika Emilia Marcinkowska

    Uniwersytet Jagielloński

  18. The H3K27M oncohistone-centred molecular mechanisms as therapeutic targets in pediatric malignant diffuse midline glioma...

    Call: SONATA BIS 14 , Panel: NZ3

    Principal investigator: dr Katarzyna Leszczyńska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  19. Exploring DMRTA2 in Glioblastoma: Epigenetic Regulation, Angiogenesis Disruption, and Biomarker Development

    Call: SONATA BIS 14 , Panel: NZ3

    Principal investigator: dr Marta Magdalena Maleszewska-Bobińska

    Uniwersytet Warszawski

  20. Improving the therapeutic potential of cytostatics through the use of abiotic metallacarboranes.

    Call: PRELUDIUM 23 , Panel: NZ7

    Principal investigator: Michalina Gos

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  21. Development of novel potential therapeutics in inflammatory bowel diseases based on nanoformulations employing senomodul...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: prof. Jakub Jerzy Fichna

    Uniwersytet Medyczny w Łodzi

  22. CD147 as a novel multifunctional modulator of podocyte metabolism and exosome biogenesis: Identification of new molecula...

    Call: OPUS 27 , Panel: NZ4

    Principal investigator: dr hab. Agnieszka Piwkowska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  23. ROS-Scavenging Magnetic Nanozymes with Remote Activation for Alzheimer Disease

    Call: M-ERA.NET 3 Call 2023 , Panel: NZ5

    Principal investigator: dr hab. Anna Ludwika Haduch

    Instytut Farmakologii PAN

  24. Is there an escape from antibioticresistant ESKAPE pathogens present in wastewater - the importance of last-chance antib...

    Call: SONATA 19 , Panel: NZ9

    Principal investigator: dr Katarzyna Natalia Grudlewska-Buda

    Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

  25. Modulation of protein interaction networks as a new therapeutic target in the treatment of hereditary retinal dystrophie...

    Call: SONATA 19 , Panel: NZ5

    Principal investigator: dr Xiaonan Liu

    Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

  26. Evaluation of the therapeutic potential of synthetic miRNA-223-3p analog in a rat model of severe asthma

    Call: SONATA 19 , Panel: NZ4

    Principal investigator: dr Wojciech Jerzy Langwiński

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  27. Actin cytoskeleton disorders as a pro-survival signaling activator and a therapeutic biomarker in Diffuse Large B-cell L...

    Call: SONATA BIS 13 , Panel: NZ5

    Principal investigator: dr Patryk Górniak

    Instytut Hematologii i Transfuzjologii

  28. Targeting IGH enhancer RNAs as a therapeutic approach in B-cell lymphoma

    Call: SONATA BIS 13 , Panel: NZ1

    Principal investigator: dr hab. Agnieszka Dzikiewicz-Krawczyk

    Instytut Genetyki Człowieka PAN

  29. Design and Development of Serine Hydroxymethyltransferase-2 (SHMT2) Inhibitors Blocking Tumor Growth

    Call: SONATA BIS 13 , Panel: NZ7

    Principal investigator: dr hab. Miłosz Ruszkowski

    Instytut Chemii Bioorganicznej PAN

  30. Exploring the Therapeutic Effects of Human Adipose Tissue Mesenchymal Stem Cell (HATMSC) line Secretome on Chronic Skin ...

    Call: SONATA BIS 13 , Panel: NZ3

    Principal investigator: dr Honorata Kraśkiewicz

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  31. The inhibition of NMDAR and TRPM4 coupling - a hope for novel therapeutic target for the treatment of the ischemic brain...

    Call: SONATA BIS 13 , Panel: NZ7

    Principal investigator: dr Bartosz Sebastian Pomierny

    Uniwersytet Jagielloński, Collegium Medicum

  32. Three to tango - biomaterials with therapeutic and regenerative multifunctionality

    Call: SONATA BIS 13 , Panel: ST11

    Principal investigator: dr Marzena Krystyna Fandzloch

    Instytut Niskich Temperatur i Badań Strukturalnych im. Włodzimierza Trzebiatowskiego PAN

  33. Prioritizing diagnostics and therapeutics of human prion diseases through integrative omics

    Call: JPND Call 2023 , Panel: NZ2

    Principal investigator: prof. Beata Katarzyna Sikorska

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  34. Extensive analysis of the immunological profile of pediatric patients with acute lymphoblastic leukemia in order to iden...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Anna Krętowska-Grunwald

    Uniwersytet Medyczny w Białymstoku

  35. Cuproptosis, a novel pathway of regulated cell death as a therapeutic target in treatment-naïve and targeted therapy-res...

    Call: OPUS 25 , Panel: NZ5

    Principal investigator: dr hab. Mariusz Łukasz Hartman

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  36. Bigels with controlled release of hydrophilic and hydrophobic therapeutic compounds as potential dressings in the treatm...

    Call: OPUS 25 , Panel: ST11

    Principal investigator: dr hab. Monika Gosecka

    Centrum Badań Molekularnych i Makromolekularnych PAN

  37. Designing Active Inhibitors of SARS-CoV-2 Methyltransferases

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Alex Jun Matsuda

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  38. Targeting undruggable proteins involved in tumorigenesis – developing and characterization of advanced nanoplatform for ...

    Call: OPUS 25 , Panel: NZ6

    Principal investigator: dr hab. Monika Bzowska

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Bitechnologii

  39. Selective PPARγ modulation by amorfrutin B as a novel therapeutic approach to chemotherapy-induced damage to mammalian b...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Bernadeta Angelika Pietrzak-Wawrzyńska

    Instytut Farmakologii PAN

  40. Therapeutic self-understanding

    Call: SONATA 18 , Panel: HS1

    Principal investigator: dr Jędrzej Piotr Grodniewicz

    Uniwersytet Jagielloński, Centrum Kopernika Badań Interdyscyplinarnych Uniwersytetu Jagiellońskiego

  41. Specific immune signatures of T cells as biomarkers of the post-COVID Syndrome and predictors of long-term health dysfun...

    Call: PRELUDIUM BIS 4 , Panel: NZ6

    Principal investigator: dr hab. Katarzyna Piwocka

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  42. Molecular insights into hypoxic tumors – for development of targeted cancer therapeutics

    Call: POLONEZ BIS 3 , Panel: NZ5

    Principal investigator: dr Marco Deiana

    Politechnika Wrocławska

  43. Computational deciphering of pro-ferroptotic cell death protein machinery as a fundamental step in the search for therap...

    Call: SONATA BIS 12 , Panel: ST4

    Principal investigator: dr hab. Karolina Anna Mikulska-Rumińska

    Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  44. Studies on the post-receptor mechanisms of TSPO in search of a novel therapeutic target of metabolic syndrome

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: dr Łukasz Kurach

    Uniwersytet Medyczny w Lublinie

  45. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Katarzyna Anna Szczepańska

    Instytut Farmakologii PAN

  46. Mechanisms and therapeutic potential of SGLT2/SGLT1 and NHE-1 inhibition in a rat model of heart failure with preserved ...

    Call: OPUS 23 , Panel: NZ5

    Principal investigator: dr hab. Urszula Mackiewicz

    CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

  47. Chemical and surgical castration of sex offenders - effective punishment, therapeutic measure or dehumanizing torture? A...

    Call: PRELUDIUM 21 , Panel: HS5

    Principal investigator: Katarzyna Teresa Jakubczak-Fopke

    Uniwersytet Gdański, Wydział Prawa i Administracji

  48. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Karolina Barbara Przepiórska-Drońska

    Instytut Farmakologii PAN

  49. The evaluation of therapeutic potential of β-caryophyllene in animal schizophrenia model - behavioral and molecular stud...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: dr Magdalena Białoń

    Instytut Farmakologii PAN

  50. Targeting of metabolic and transcriptomic cross-talk between leukemic cells and macrophages as a therapeutic strategy in...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Baran Natalia

    Instytut Hematologii i Transfuzjologii