Projects funded by the NCN

Destabilization of neuronal morphology in chronic inflammation: molecular mechanisms and identification of potential the...

Call: OPUS 29 , Panel: NZ5

Principal investigator: prof. Jacek Ryszard Jaworski

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Metal chelators affecting iron metabolism as a tool to investigate undiscovered aspects of ferroptosis

Call: OPUS 28 , Panel: NZ5

Principal investigator: dr hab. Anna Dominika Mrozek-Wilczkiewicz

Politechnika Śląska

From open-shell materials to molecular recognition: synthesis of polycyclic aromatic compounds through cyclotrimerizatio...

Call: SONATA 20 , Panel: ST4

Principal investigator: dr Arseni Borissov

Uniwersytet Wrocławski

Identifying early biomarkers and molecular targets for therapeutic intervention in right ventricular dysfunction

Call: OPUS 28 , Panel: NZ5

Principal investigator: prof. Przemysław Błyszczuk

Uniwersytet Jagielloński

Molecular insights into NAD+ metabolism in Huntington's disease: role in pathophysiology and preclinical assessment of t...

Call: OPUS 28 , Panel: NZ5

Principal investigator: dr hab. Marta Urszula Tomczyk

Gdański Uniwersytet Medyczny

Quad-TNT: Quadruplex-Targeted Photo-Therapy for Triple-Negative Tumors

Call: SONATA BIS 14 , Panel: NZ5

Principal investigator: dr Marco Deiana

Politechnika Wrocławska

Exploring the impact of somatic expansion rates on quantitative progression marker candidates (Voice) in early stages of...

Call: JPND Call 2024 , Panel: NZ5

Principal investigator: dr Grzegorz Przemysław Witkowski

Wojskowy Instytut Medycyny Lotniczej

Molecular factors and pathomechanism of cancer-associated cachexia.

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr hab. Marcin Tomasz Skrzypski

Gdański Uniwersytet Medyczny

The comprehensive molecular and clinical characterization of Crooke's cell corticotroph pituitary tumors

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Szymon Piotr Baluszek

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Genetic background of chromothripsis, its role in clonal evolution and response to therapy in childhood acute lymphoblas...

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr hab. Agata Karolina Pastorczak

Uniwersytet Medyczny w Łodzi

Elimination of molecular recognition limitations in electrochemical DNA-sensors with mixed homophasic-heterophasic mecha...

Call: PRELUDIUM 23 , Panel: ST4

Principal investigator: Anna Magdalena Szymczyk

Politechnika Warszawska

Functional studies of TPM2 gene mutation responsible for the hereditary form of clubfoot disease

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Akshaya Ramanujam

Uniwersytet Medyczny w Lublinie

Molecular basis of the function of WRKY transcription factors as pivotal regulators of plant responses to stress

Call: OPUS 27 , Panel: NZ9

Principal investigator: dr Marta Grzechowiak

Instytut Chemii Bioorganicznej PAN

The role of miRNAs (miR30a, miR30b, miR30c) in RARγ expression in acute myeloid leukemia (AML)

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Rafał Skopek

Instytut Genetyki i Hodowli Zwierząt PAN

Insufficiency of antioxidant mechanisms and dysregulation of circulating miRNA profiles as a cause of delayed cerebral i...

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Karol Marek Wiśniewski

Uniwersytet Medyczny w Łodzi

Evaluation of the relationship between doxorubicin resistance, epithelial-mesenchymal plasticity, and effects of selecte...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Dominika Kunachowicz

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Spatial visual transcriptomics approach of male and female gonad - validation of the role of candidate infertility genes...

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr hab. Marta Anna Olszewska

Instytut Genetyki Człowieka PAN

Comprehensive structural and functional analysis of p53 mRNA to identify secondary and tertiary RNA structures important...

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Leszek Michał Błaszczyk

Instytut Chemii Bioorganicznej PAN

The association between the repair of oxidative DNA lesions and Th17/Treg cell homeostasis in Patients with Rheumatoid A...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Gabriela Filipowicz

Instytut Reumatologii im. prof. dr hab. med. Eleonory Reicher

Molecular mechanisms underlying the polycystic ovary syndrome

Call: OPUS 26 , Panel: NZ5

Principal investigator: prof. Nafis Ahmed Rahman

Uniwersytet Medyczny w Białymstoku

Multichromophoric open-cage silsesquioxanes as quantitative optical anion sensors

Call: SONATA 19 , Panel: ST5

Principal investigator: dr Magdalena Maria Grzelak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

The role of oxidative stress, inflammation, disorders of purine metabolism, urea cycle and angiogenesis at the molecular...

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Paulina Wigner-Jeziorska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Tautomerism-coupled subcomponents self-assembly – a new tool for the construction of stimuli-responsive molecular capsul...

Call: OPUS 26 , Panel: ST4

Principal investigator: dr hab. Bartosz Jakub Szyszko

Uniwersytet Wrocławski, Wydział Chemii

The mechanism of competition of mutant p53 gain-of-function and major oncogene CMYC in gastric cancer.

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Marcin Mikołaj Grochowski

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Cuproptosis, a novel pathway of regulated cell death as a therapeutic target in treatment-naïve and targeted therapy-res...

Call: OPUS 25 , Panel: NZ5

Principal investigator: dr hab. Mariusz Łukasz Hartman

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Molecular profiling of soft tissue sarcomas in tumor and peripheral blood in terms of response to treatment and early de...

Call: OPUS 25 , Panel: NZ5

Principal investigator: prof. Piotr Łukasz Rutkowski

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Epigenetic biomarkers of destruction of residual beta cells after diagnosis of type 1 diabetes – links to diabetic ketoa...

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Arkadiusz Mariusz Michalak

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Ścieżka związana z translacją i aktywowane retrotranspozony jako podłoże choroby neurodegeneracyjnej ALS skorelowanej z ...

Call: OPUS 25 , Panel: NZ5

Principal investigator: dr hab. Katarzyna Dorota Raczyńska

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Assessing ovarian cancer molecular heterogeneity by NMR-based metabolomics, spatially resolved transcriptomics and metab...

Call: OPUS 25 , Panel: NZ5

Principal investigator: prof. Maria Bożena Sokół

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Activation of retrotransposons underlying neurodegenerative disease ALS related to mutations in FUS protein

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Patrycja Agnieszka Świergiel

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

The effects of myopathy-causing mutations in TPM2 on tropomyosin-dependent regulation of the thin filament length

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Recep Küçükdoğru

Uniwersytet Kazimierza Wielkiego

Chasing lithium: direct lithium salt extraction and purification from mixtures using stimuli-responsive smart" molecular...

Call: OPUS 24 , Panel: ST5

Principal investigator: dr Kajetan Dąbrowa

Instytut Chemii Organicznej Polska Akademia Nauk

Molecular insights into hypoxic tumors – for development of targeted cancer therapeutics

Call: POLONEZ BIS 3 , Panel: NZ5

Principal investigator: dr Marco Deiana

Politechnika Wrocławska

The mechanism of RNA recognition by KH-domain proteins KhpA and KhpB from Streptococcus pneumoniae

Call: OPUS 24 , Panel: NZ1

Principal investigator: prof. Mikołaj Olejniczak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

CatchT21: Deciphering molecular basis of RNA amplification in pathogenesis of Trisomy 21

Call: OPUS 24 , Panel: NZ5

Principal investigator: dr Magdalena Maria Masłoń

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii

Modifiers of Muscleblind-like genes expression in health and disease.

Call: SONATA BIS 12 , Panel: NZ5

Principal investigator: dr hab. Ewa Agnieszka Stępniak-Konieczna

Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa, Ogrodnictwa i Biotechnologii

Molecular and cellular mechanisms responsible for the initiation and progression of clear cell renal cell carcinoma

Call: OPUS 23 , Panel: NZ5

Principal investigator: dr hab. Katarzyna Miękus

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

New strategy for overcoming resistance to chemotherapy of ovarian cancer by modulation of the canonical and non-canonica...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr hab. Radosław Januchowski

Uniwersytet Zielonogórski, Collegium Medicum

Brain GABAB receptors as determinants of obesity phenotypes: evaluation of adolescent female and male rats

Call: OPUS 22 , Panel: NZ5

Principal investigator: prof. Małgorzata Maria Filip

Instytut Farmakologii PAN

Small-molecule inhibitors of protein aggregation and ER stress as a novel strategy against neurodegeneration in the cour...

Call: PRELUDIUM BIS 3 , Panel: NZ5

Principal investigator: prof. Ireneusz Jacek Majsterek

Uniwersytet Medyczny w Łodzi

Identification of molecular mechanism underlying the phenotype development of Emery-Dreifuss muscular dystrophy.

Call: SONATA 17 , Panel: NZ5

Principal investigator: dr Katarzyna Piekarowicz

Uniwersytet Wrocławski, Wydział Biotechnologii

Expression, regulation and function of super-enhancer non-coding RNAs in Diffuse Large B-Cell Lymphoma (DLBCL)

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: dr Sonia Maria Dębek

Instytut Hematologii i Transfuzjologii

The role of miR-27b-5p in Head and Neck Squamous Cell Carcinoma.

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: Joanna Kozłowska-Masłoń

Wielkopolskie Centrum Onkologii

Evaluation of NOTCH1- and NOTCH3-dependent anticancer drug resistance in a 2D and 3D model of Head and Neck Squamous Cel...

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: dr Joanna Elżbieta Kałafut

Uniwersytet Medyczny w Lublinie

Epigenetic Reprograming and All-trans-Retinoic Acid in Therapy of Myelodysplastic Syndromes

Call: OPUS 21 , Panel: NZ5

Principal investigator: prof. Artur Zygmunt Zelent

Instytut Genetyki i Hodowli Zwierząt PAN

Molecular basis of the differences in RNA recognition by the FinO domain proteins

Call: PRELUDIUM 20 , Panel: NZ1

Principal investigator: Maciej Michał Basczok

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Analysis of miRNA in extracellular vesicles from respiratory tract associated with asthma pathomechanism in pediatric po...

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: Dominika Magdalena Ambrożej

Warszawski Uniwersytet Medyczny

Iron chelators as tyrosine kinase inhibitors - a new strategy for the treatment of glioblastoma multiforme

Call: PRELUDIUM BIS 2 , Panel: NZ5

Principal investigator: dr hab. Anna Dominika Mrozek-Wilczkiewicz

UNIWERSYTET ŚLĄSKI, Wydział Nauk Ścisłych i Technicznych

Clinical effect and molecular mechanisms of action of s-adenosylmethionine (SAMe) in patients with primary sclerosing ch...

Call: PRELUDIUM BIS 2 , Panel: NZ5

Principal investigator: prof. Piotr Milkiewicz

Warszawski Uniwersytet Medyczny

The Molecular Pathway Regulating the Stability of β-Dystroglycan

Call: SONATA 16 , Panel: NZ5

Principal investigator: dr Bhola Pradhan

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii