Projects funded by the NCN

Oligonucleotide-based fluorescent probes at the lipid monolayer / aqueous solution interface. Monitoring of the concentr...

Call: OPUS 1 , Panel: ST4

Principal investigator: prof. Bernard Juskowiak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Metallacrowns as ligands for higher-order DNA structures.

Call: PRELUDIUM 7 , Panel: ST4

Principal investigator: Ewa Rajczak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

RNA hybrid duplex-quadruplex structures with dual functionality as a new tool for silecing of gene expression

Call: OPUS 7 , Panel: ST5

Principal investigator: prof. Zofia Gdaniec

Instytut Chemii Bioorganicznej PAN

Antisense oligonucleotides as tools specifically binding viral G-quadruplexes and their experimental verification

Call: OPUS 25 , Panel: ST4

Principal investigator: dr Marta Szabat

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Molecular insights into hypoxic tumors – for development of targeted cancer therapeutics

Call: POLONEZ BIS 3 , Panel: NZ5

Principal investigator: dr Marco Deiana

Politechnika Wrocławska

Reversible modulation of G-quadruplex functions using photoresponsive ligands - in vitro and cellular studies

Call: SONATA 17 , Panel: ST4

Principal investigator: dr Marta Dudek

Politechnika Wrocławska

Close Encounters of the Third Kind: what happens when ribonuclease Dicer encounters in the cell RNA and DNA adopting G-q...

Call: OPUS 21 , Panel: NZ2

Principal investigator: dr hab. Anna Kurzyńska-Kokorniak

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Thrombin binding aptamer with expanded chemical diversity as potential anticoagulant and anticancer agent

Call: OPUS 21 , Panel: NZ7

Principal investigator: dr Weronika Kotkowiak

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Anti-cancer strategy based on the induced G-quadruplex formation. Structural and biological properties of ligand-RNA/mRN...

Call: SONATA 16 , Panel: ST4

Principal investigator: dr Dorota Gudanis

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Foldback triplex-forming oligonucleotides as novel tools for G-quadruplex unfolding and selective inhibition of c-Myc on...

Call: OPUS 19 , Panel: NZ7

Principal investigator: dr hab. Anna Pasternak

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Non-linear optical properties of organometallic assemblies for biophotnic applications

Call: OPUS 18 , Panel: ST4

Principal investigator: dr hab. Katarzyna Matczyszyn

Politechnika Wrocławska

Feature exploration and modelling of quadruplex structures

Call: OPUS 18 , Panel: ST6

Principal investigator: dr hab. Marta Szachniuk

Politechnika Poznańska, Wydział Informatyki

Novel bispecific G-quadruplex conjugates as potential anticancer agents

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: Carolina Pereira Roxo

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

The G-rich sequences in the influenza A virus genome – structural features and potential biological function in viral re...

Call: SONATA 15 , Panel: NZ6

Principal investigator: dr Marta Szabat

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Exploring the sequence-structure relationship as a starting point for the design of DNA G-quadruplexes with a given topo...

Call: OPUS 18 , Panel: ST4

Principal investigator: dr hab. Jacek Czub

Politechnika Gdańska

Hybrid chiroptical systems based on photoresponsive molecules and biomaterials

Call: PRELUDIUM 15 , Panel: ST5

Principal investigator: dr Marta Dudek

Politechnika Wrocławska

Pioneering structural and functional studies of miRNA G-quadruplexes

Call: SONATINA 2 , Panel: NZ1

Principal investigator: dr Agnieszka Belter

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Heme and G-quadruplexes: an overlooked function of heme oxygenases?

Call: OPUS 13 , Panel: NZ3

Principal investigator: prof. Alicja Józkowicz

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Structural determinants of anticancer properties of G-rich oligonucleotides

Call: OPUS 13 , Panel: NZ7

Principal investigator: dr hab. Anna Pasternak

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Anticoagulant and antiproliferative properties of novel thrombin binding aptamer analogues

Call: PRELUDIUM 10 , Panel: NZ5

Principal investigator: Weronika Kotkowiak

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Interaction of oligonucleotide-based fluorescent probes and Langmuir monolayer, contaning silver nanoclusters (Ag NCs), ...

Call: PRELUDIUM 10 , Panel: ST4

Principal investigator: Angelika Świtalska

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Modeling 3D structures and dynamics of RNA complexes with metal ions, with particular emphasis on the formation of non-c...

Call: SONATA 9 , Panel: NZ1

Principal investigator: dr Dorota Niedziałek

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk