Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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The G-rich sequences in the influenza A virus genome – structural features and potential biological function in viral replication cycle

2019/35/D/NZ6/01479

Keywords:

influenza virus RNA secondary structure RNA quadruplex minireplicon viral replication cycle

Descriptors:

  • NZ1_4: Structural biology
  • NZ6_5: Virology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Marta Maria Szabat 

Number of co-investigators in the project: 4

Call: SONATA 15 - announced on 2019-09-16

Amount awarded: 1 486 800 PLN

Project start date (Y-m-d): 2020-09-01

Project end date (Y-m-d): 2024-08-31

Project duration:: 48 months (the same as in the proposal)

Project status: Project completed

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (8)
  1. Identification and Structural Aspects of G-Quadruplex-Forming Sequences from the Influenza A Virus Genome
    Authors:
    Maria Tomaszewska, Marta Szabat, Karolina Zielińska, Ryszard Kierzek
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 6031), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22116031 - link to the publication
  2. Examples of Structural Motifs in Viral Genomes and Approaches for RNA Structure Characterization
    Authors:
    Maria Nalewaj Marta Szabat
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 15917-15936), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms232415917 - link to the publication
  3. RNA Secondary Structure as a First Step for Rational Design of the Oligonucleotides towards Inhibition of Influenza A Virus Replication
    Authors:
    Marta Szabat, Dagny Lorent, Tomasz Czapik, Elżbieta Kierzek, Ryszard Kierzek
    Academic press:
    Pathogens (rok: 2020, tom: 9, strony: 925), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pathogens9110925 - link to the publication
  4. Identification and Structural Aspects of G-Quadruplex-Forming Sequences from the Influenza A Virus Genome
    Authors:
    Maria Tomaszewska, Marta Szabat, Karolina Zielińska, Ryszard Kierzek
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 6031), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22116031 - link to the publication
  5. RNA Secondary Structure as a First Step for Rational Design of the Oligonucleotides towards Inhibition of Influenza A Virus Replication
    Authors:
    Marta Szabat, Dagny Lorent, Tomasz Czapik, Elżbieta Kierzek, Ryszard Kierzek
    Academic press:
    Pathogens (rok: 2020, tom: 9, strony: 925), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pathogens9110925 - link to the publication
  6. RNA Secondary Structure as a First Step for Rational Design of the Oligonucleotides towards Inhibition of Influenza A Virus Replication
    Authors:
    Marta Szabat, Dagny Lorent, Tomasz Czapik, Elżbieta Kierzek, Ryszard Kierzek
    Academic press:
    Pathogens (rok: 2020, tom: 9, strony: 925), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pathogens9110925 - link to the publication
  7. Examples of Structural Motifs in Viral Genomes and Approaches for RNA Structure Characterization
    Authors:
    Maria Nalewaj Marta Szabat
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 15917-15936), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms232415917 - link to the publication
  8. Identification and Structural Aspects of G-Quadruplex-Forming Sequences from the Influenza A Virus Genome
    Authors:
    Maria Tomaszewska, Marta Szabat, Karolina Zielińska, Ryszard Kierzek
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 6031), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22116031 - link to the publication

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