Projects funded by the NCN

Identification of new, clinically relevant genetic and epigenetic aberrations by next-generation sequencing in chronic m...

Call: HARMONIA 6 , Panel: NZ5

Principal investigator: dr Tomasz Stokłosa

Warszawski Uniwersytet Medyczny, Wydział Lekarski

Mechanism of SYK-mediated suppression of differentiation and apoptosis in acute myeloid leukemia (AML)

Call: PRELUDIUM 6 , Panel: NZ5

Principal investigator: dr Anna Polak

Instytut Hematologii i Transfuzjologii

The regulation of vitamin D receptor expression by retinoids

Call: PRELUDIUM 6 , Panel: NZ3

Principal investigator: Aleksandra Marchwicka

Uniwersytet Wrocławski, Wydział Biotechnologii

Inhibition of p21-Activated Kinase (PAK) as a new molecular target in the treatment of chronic myeloid leukemia (CML)

Call: OPUS 6 , Panel: NZ7

Principal investigator: dr hab. Sylwia Flis

Narodowy Instytut Leków

The role of nucelophosmin-1 exon 12 abnormalities in acute myeloid leukemias and myelodyplastic syndrome

Call: HARMONIA 5 , Panel: NZ5

Principal investigator: dr hab. Krzysztof Giannopoulos

Uniwersytet Medyczny w Lublinie, II Wydział Lekarski z Oddziałem Anglojęzycznym

Investigation of the molecular mechanisms of anti-leukemic activity of SK053, a small molecule compound targeting enzyme...

Call: SONATA BIS 3 , Panel: NZ5

Principal investigator: prof. Dominika Nowis

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Investigation of the role of ficolins in anti-microbial defense in patients suffering from acute myeloid leukaemia, unde...

Call: PRELUDIUM 4 , Panel: NZ6

Principal investigator: Anna Sokołowska

Instytut Biologii Medycznej PAN

The novel role of CD44 protein in the bone marrow microenvironment-mediated metabolic remodeling of chronic myeloid leuk...

Call: PRELUDIUM 22 , Panel: NZ3

Principal investigator: Laura Turos-Korgul

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

Differences in the glycoproteomic profile of acute myeloid leukemia (AML) between cytogenetic and risk groups according ...

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Tomasz Pieńkowski

Uniwersytet Medyczny w Białymstoku

Investigating the role of fibroblast growth factor receptors and STAT transcription factors in the targeted therapy of a...

Call: PRELUDIUM BIS 4 , Panel: NZ5

Principal investigator: prof. Ewa Marcinkowska

Uniwersytet Wrocławski, Wydział Biotechnologii

Inhibiting the Mitochondrial Intermembrane Space Assembly pathway as a newapproach to prevent metabolic reprogramming of...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr hab. Carlo Vascotto

Instytut Hematologii i Transfuzjologii

Verification of personalized therapeutic strategy based on Integrated Stress Response inhibition for myeloid neoplasms w...

Call: OPUS 21 , Panel: NZ5

Principal investigator: dr hab. Katarzyna Piwocka

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

Identifying the hematopoietic and leukemic stem cell niches

Call: MOZART 1 , Panel: NZ3

Principal investigator: dr Krzysztof Szade

Uniwersytet Jagielloński

Linking stress response with genomic instability in chronic myeloid leukaemia cells; role of the PERK-eIF2α phosphorylat...

Call: OPUS 1 , Panel: NZ3

Principal investigator: dr hab. Katarzyna Piwocka

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Epigenetic effect on therapeutic activities of all-trans-retinoic acid in acute myeloid leukemia

Call: OPUS 17 , Panel: NZ5

Principal investigator: prof. Arthur Zelent

Wojskowy Instytut Higieny i Epidemiologii im. gen. Karola Kaczkowskiego

Immunological and molecular characteisitics of chronic myeloid leukemia patients after stopping imatinib

Call: OPUS 16 , Panel: NZ6

Principal investigator: prof. Krzysztof Giannopoulos

Uniwersytet Medyczny w Lublinie, Wydział Lekarski

Deciphering molecular mechanism of CDK8 kinase inhibitors action in acute myeloid leukemia

Call: SONATA BIS 8 , Panel: NZ2

Principal investigator: dr hab. Michał Mikula

Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy

Tracing the roots of leukemia - how preleukemic hematopoietic stem cells contribute to acute lymphoid and myeloid leukem...

Call: HARMONIA 10 , Panel: NZ5

Principal investigator: dr Krzysztof Szade

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Determining the role of basigin in multiple myeloma and acute myeloid leukaemia development

Call: PRELUDIUM 15 , Panel: NZ5

Principal investigator: Piotr Łacina

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Phosphorylation of translation initiation factor eIF2alpha as regulator of synthesis of proinflammatory and signaling cy...

Call: PRELUDIUM 10 , Panel: NZ3

Principal investigator: Wioleta Dudka-Ruszkowska

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

Characterization of aberrant mechanisms of telomere maintenance in chronic myeloid leukemia - the role of POT1 and RAP1 ...

Call: OPUS 10 , Panel: NZ5

Principal investigator: dr Tomasz Stokłosa

Warszawski Uniwersytet Medyczny, Wydział Lekarski

Products of DNA demethylation and deamination pathways as new biomarkers of development and predictors of the outcome in...

Call: OPUS 10 , Panel: NZ5

Principal investigator: dr hab. Daniel Gackowski

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny