Projects funded by the NCN
Verification of personalized therapeutic strategy based on Integrated Stress Response inhibition for myeloid neoplasms with PTPN11 mutations.
2021/41/B/NZ5/04077
Keywords:
myeloid leukemia ISR Integrated Stress response resistance PTPN11 NGS STAT5 immunosupression Treg bone marrow microenvironment leukemia mouse models NSG immunodeficient mice PDX models
Descriptors:
- NZ5_7: Human disease treatment
- NZ5_3: Pathogenesis of human diseases
Panel:
NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution :
Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 9
Call: OPUS 21 - announced on 2021-03-15
Amount awarded: 2 917 200 PLN
Project start date (Y-m-d): 2022-04-01
Project end date (Y-m-d): 2026-03-31
Project duration:: 48 months (the same as in the proposal)
Project status: Pending project
Project description
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