Projects funded by the NCN

Biotechnological method for production of 8-prenylnaringenin for application in treatment of inflammatory skin diseases

Call: SONATA 20 , Panel: ST8

Principal investigator: dr Jan Paweł Krzysztoforski

Politechnika Warszawska

The role of bile acid receptor TGR5 in insulin-dependent regulation of podocyte function and glomerular filtration barri...

Call: SONATA 20 , Panel: NZ4

Principal investigator: dr Patrycja Rachubik

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

Analysis of the transmission of overweight/obesity in the mother-breastmilk-child triad in relation to maternal cardiome...

Call: OPUS 28 , Panel: NZ9

Principal investigator: dr Monika Anna Zielińska-Pukos

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie

CHI3L1 (YKL40) in ischemic stroke: impact on brain microenvironment and motor function recovery

Call: SONATA BIS 14 , Panel: NZ4

Principal investigator: dr hab. Anna Róża Malik

Uniwersytet Warszawski

Characterization of ANGPTL4 production in the peritoneum

Call: PRELUDIUM 23 , Panel: NZ4

Principal investigator: Joanna Marta Żuraszek-Szymańska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Development and optimization of a vasculature-on-a-chip approach to investigateendothelial cell response to proinflammat...

Call: OPUS 27 , Panel: ST4

Principal investigator: prof. Zbigniew Brzózka

Politechnika Warszawska

The probiotic potential of Lactococcus strains to counteract inflammation-induced intestinal barrier disruption: an in v...

Call: PRELUDIUM 23 , Panel: NZ9

Principal investigator: Olha Kostiuchenko

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Small molecule modulators of the tumor necrosis factor alpha signaling pathway for the inhibition of inflammatory proces...

Call: OPUS 27 , Panel: NZ7

Principal investigator: prof. Tadeusz Holak

Uniwersytet Gdański

Can the bactericidal and immunomodulatory effects of ceragenins be used in the development of new methods of treating ac...

Call: PRELUDIUM 23 , Panel: NZ6

Principal investigator: Agata Aleksandra Lesiak

Uniwersytet Jana Kochanowskiego w Kielcach

The impact of physical activity on the gut-brain axis molecular adaptation to chronic stress

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Julia Wiktoria Morys

Akademia Wychowania Fizycznego im. Jerzego Kukuczki w Katowicach

Using DNA methylation markers and epigenetic clocks as an innovative tool to assess health, risk indicators, and manage ...

Call: OPUS 27 , Panel: NZ7

Principal investigator: dr hab. Ewelina Maria Pośpiech

Pomorski Uniwersytet Medyczny w Szczecinie

Supporting the protective functions of the cervicovaginal epithelium and vaginal microbiota by witch hazel bark and its ...

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Weronika Monika Skowrońska

Warszawski Uniwersytet Medyczny

Investigations on polymeric immunoglobulin receptor (pIgR) expression in equine intestinal epithelial cells in the conte...

Call: SONATA 19 , Panel: NZ6

Principal investigator: dr Agnieszka Teresa Żak-Bochenek

Uniwersytet Przyrodniczy we Wrocławiu

The role of oxidative stress, inflammation, disorders of purine metabolism, urea cycle and angiogenesis at the molecular...

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Paulina Wigner-Jeziorska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Bacterial outer membrane vesicles and caspase-4-mediated activation of endothelial cells induces secretion of immunomodu...

Call: SONATA 19 , Panel: NZ6

Principal investigator: dr Wojciech Marek Cypryk

Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

Does organic sulfur reduce the high fat diet-induced inflammation in benign prostate hyperplasia?

Call: SONATA 19 , Panel: NZ7

Principal investigator: dr Karolina Kowalska

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Secondary metabolites of selected dietary ingredients as factors preventing leakage of the intestinal epithelium and sha...

Call: OPUS 26 , Panel: NZ9

Principal investigator: dr hab. Monika Ewa Czerwińska

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

Novel aspects of the mechanisms of vascular toxicity of tyrosine kinase inhibitors: studies on their proinflammatory act...

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr Tomasz Krzysztof Prajsnar

Uniwersytet Jagielloński, Wydział Biologii

The role of proteolytic cleavage in molecular functions fulfilled by MCPIP.

Call: PRELUDIUM 2 , Panel: NZ1

Principal investigator: dr Łukasz Dariusz Skalniak

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Raman4Cell2Cell: Uncovering the reciprocal interactions of leukocytes and endothelial cells by (stimulated) Raman imagin...

Call: OPUS 26 , Panel: ST4

Principal investigator: dr Aleksandra Maria Borek-Dorosz

Uniwersytet Jagielloński, Wydział Chemii

The effect of omega-3 polyunsaturated acids supplementation on endothelial function, oxidative stress, platelet aggregat...

Call: OPUS 2 , Panel: NZ5

Principal investigator: dr hab. Grzegorz Paweł Gajos

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Immunomodulation of microglia-oligodendrocyte interaction in preventing thebrain white matter disorders in perinatal per...

Call: PRELUDIUM 22 , Panel: NZ3

Principal investigator: Justyna Magdalena Gargaś

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

The influence of NF kappa beta-dependent inflammation induced by oxidative stress on cellular senescence in obstructive ...

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Szymon Jan Turkiewicz

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

The anti-inflammatory potential of extracellular vesicles of the parasitic nematode Anisakis simplex in human gastric an...

Call: OPUS 25 , Panel: NZ6

Principal investigator: dr Robert Stryiński

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

Search for novel IKK-β inhibitors in the context of diseases with neuroinflammatory origin – structure-based drug design...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Emilia Aleksandra Sługocka

Uniwersytet Jagielloński, Collegium Medicum

The impact of probiotic supplementation on outcomes of surgical treatment of obesity: exploring the interplay between gu...

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Marta Potrykus

Gdański Uniwersytet Medyczny, Wydział Lekarski

Cross-talk between endothelium and perivascular adipose tissue upon inflammation: high-resolution imaging of adipocytes ...

Call: PRELUDIUM 22 , Panel: ST4

Principal investigator: Ewa Stanek

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

The influence of genetic variability of pro- and anti-inflammatory cytokines on the risk of knee ligament injury in elit...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Katarzyna Małgorzata Lorenz

Akademia Wychowania Fizycznego Józefa Piłsudskiego w Warszawie

Novel metastable titanium beta-phase alloys based on the Ti-Mo system for applications in the modular total hip replacem...

Call: SONATINA 7 , Panel: ST11

Principal investigator: dr Agata Joanna Sotniczuk

Narodowe Centrum Badań Jądrowych

Impact of uremic carbamylation on RAA system and endothelial dysfunction

Call: OPUS 24 , Panel: NZ4

Principal investigator: prof. Piotr Mydel

Uniwersytet Jagielloński

Specific immune signatures of T cells as biomarkers of the post-COVID Syndrome and predictors of long-term health dysfun...

Call: PRELUDIUM BIS 4 , Panel: NZ6

Principal investigator: dr hab. Katarzyna Piwocka

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

The discovery of multifactorial regulation at epigenetic memory of active gene expression state

Call: SONATA 18 , Panel: NZ2

Principal investigator: dr Paweł Sławomir Mikulski

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Are MCPIP1 and MCPIP3 analogous or opposite players in the maintenance of skin function?

Call: SONATA 18 , Panel: NZ3

Principal investigator: dr Agata Lichawska-Cieślar

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Three-phase drug carriers - design towards a prolonged release, development of a transport model and its verification. C...

Call: PRELUDIUM BIS 4 , Panel: ST8

Principal investigator: prof. Anna Trusek

Politechnika Wrocławska

The role of CDK5 in inflammatory reaction in experimental model of Alzheimer's disease

Call: OPUS 2 , Panel: NZ3

Principal investigator: dr hab. Grzegorz Arkadiusz Czapski

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

A double whammy for the NF-κB signalling pathway: development of TAK1 and IKKβ degraders against inflammation-driven dis...

Call: OPUS 24 (LAP) , Panel: NZ7

Principal investigator: dr hab. Anna Karolina Więckowska

Uniwersytet Jagielloński, Collegium Medicum

Dissecting the tumoricidal potential of ILC2s in melanoma

Call: SONATA BIS 12 , Panel: NZ6

Principal investigator: dr Marek Wagner

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

Alpha-mannosidases of N-glycosylation pathway in gastrointestinal epithelial cells. Research on their role in glycome mo...

Call: SONATA BIS 12 , Panel: NZ1

Principal investigator: dr Paweł Krzysztof Link-Lenczowski

Uniwersytet Jagielloński, Collegium Medicum

The beneficial health potential of blackthorn fruits (Prunus spinosa L.) in gastrointestinal tract inflammations – in vi...

Call: PRELUDIUM 21 , Panel: NZ9

Principal investigator: dr Anna Katarzyna Magiera

Uniwersytet Medyczny w Łodzi, Wydział Farmaceutyczny

Molecular and cellular mechanisms responsible for the initiation and progression of clear cell renal cell carcinoma

Call: OPUS 23 , Panel: NZ5

Principal investigator: dr hab. Katarzyna Miękus

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Effect of liraglutide on inflammatory response of peripheral blood mononuclear cells (PBMCs) in subjects at risk of type...

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Marta Dobrzycka

Uniwersytet Medyczny w Białymstoku

Anti-inflammatory effect of senotherapeutic agents on gingival fibroblasts as a potential therapy for periodontitis

Call: PRELUDIUM 21 , Panel: NZ5

Principal investigator: Alicja Danuta Płonczyńska

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

The crosstalk between kynurenine pathway of L-tryptophan degradation andinflammation in acute pulmonary embolism and pos...

Call: OPUS 23 , Panel: NZ5

Principal investigator: prof. Piotr Pruszczyk

Warszawski Uniwersytet Medyczny

Effect of intestinal microbiota modulation induced by the chicory inulin-type β-fructans on metabolic parameters and bio...

Call: OPUS 23 , Panel: NZ9

Principal investigator: dr hab. Urszula - Krupa-Kozak

Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk

Extracellular vimentin as a signaling molecule in the pathogenesis of inflammation and central nervous system damage in ...

Call: PRELUDIUM 21 , Panel: NZ6

Principal investigator: Łukasz Jerzy Suprewicz

Uniwersytet Medyczny w Białymstoku, Wydział Lekarski z Oddziałem Stomatologii i Oddziałem Nauczania w Języku Angielskim

Immunomodulating properties of pre-fermented whey beverage enriched with chokeberry juice and colostrum

Call: PRELUDIUM BIS 3 , Panel: NZ9

Principal investigator: prof. Barbara Elżbieta Wróblewska

Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk

Effect of COVID-19 on the level of advanced glycation end products (AGEs) and other markers of oxidative stress in patie...

Call: SONATA 17 , Panel: NZ5

Principal investigator: dr Agnieszka Wiesława Bronowicka-Szydełko

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

The assessment of the susceptibility of the lung endothelium to infections with respiratory viruses and its involvement ...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr hab. Maciej Zygmunt Chałubiński

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

In search for novel markers of senescence and causes of senescent cells accumulation in atherosclerotic plaque

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr hab. Agnieszka Anna Jaźwa-Kusior

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

New approach to the treatment of Alzheimer's disease targetingresolution of inflammation and modulation of biomechanical...

Call: OPUS 22 , Panel: NZ4

Principal investigator: prof. Agnieszka Basta-Kaim

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk