Projects funded by the NCN

The Hidden Players: How HIF-2-Regulated MicroRNAs Shape Endothelial Adaptation to Hypoxia

Call: PRELUDIUM 24 , Panel: NZ3

Principal investigator: Anna Maria Barton

Uniwersytet Wrocławski

4B for LDs: Biodiversity, Biogenesis, Biodegradation and Biomedicine of lipid droplets in age-dependent vascular dysfunc...

Call: SONATA BIS 14 , Panel: NZ7

Principal investigator: dr hab. Marta Zofia Pacia

Uniwersytet Jagielloński

Changes in protein citrullination profile and chromatin structure induced by peptidyl-arginine deiminases activity and t...

Call: PRELUDIUM 23 , Panel: NZ3

Principal investigator: Oskar Kazimierz Ciesielski

Uniwersytet Łódzki

Development and optimization of a vasculature-on-a-chip approach to investigateendothelial cell response to proinflammat...

Call: OPUS 27 , Panel: ST4

Principal investigator: prof. Zbigniew Brzózka

Politechnika Warszawska

Heterogeneity of perivascular adipose tissue in the browning process: at the crossroads of single-cell Raman spectroscop...

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Krzysztof Czamara

Uniwersytet Jagielloński

Different plastics nanoparticles as potential threat for the cardiovascular physiology -evaluation of the effects on blo...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Joanna Maria Kołodziejczyk-Czepas

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Bacterial outer membrane vesicles and caspase-4-mediated activation of endothelial cells induces secretion of immunomodu...

Call: SONATA 19 , Panel: NZ6

Principal investigator: dr Wojciech Marek Cypryk

Centrum Badań Molekularnych i Makromolekularnych PAN

Mitochondrial targets of flozins in endothelial cells - a new approach to the prevention, diagnosis and therapy of heart...

Call: OPUS 26 , Panel: NZ4

Principal investigator: dr hab. Barbara Anna Kutryb-Zając

Gdański Uniwersytet Medyczny, Wydział Lekarski

Endothelial bioenergetics as a novel target for vascular protection – unveiling the mitochondrial mechanisms of lipid-lo...

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: dr Alicja Małgorzata Braczko

Gdański Uniwersytet Medyczny, Wydział Lekarski

The Role of the Mitochondrial Unfolded Protein Response (UPRmt) in Endothelial Function: a Possible Novel Target for the...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Sylwester Tycjan Mosiołek

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Cross-talk between endothelium and perivascular adipose tissue upon inflammation: high-resolution imaging of adipocytes ...

Call: PRELUDIUM 22 , Panel: ST4

Principal investigator: Ewa Stanek

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Impact of uremic carbamylation on RAA system and endothelial dysfunction

Call: OPUS 24 , Panel: NZ4

Principal investigator: prof. Piotr Mydel

Uniwersytet Jagielloński

Specific immune signatures of T cells as biomarkers of the post-COVID Syndrome and predictors of long-term health dysfun...

Call: PRELUDIUM BIS 4 , Panel: NZ6

Principal investigator: dr hab. Katarzyna Piwocka

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

The impact of physical activity on brain resilience to chronic stress and the mediating role of blood-brain barrier.

Call: OPUS 24 , Panel: NZ7

Principal investigator: dr Marta Maria Nowacka-Chmielewska

Akademia Wychowania Fizycznego im. Jerzego Kukuczki w Katowicach, Instytut Fizjoterapii i Nauk o Zdrowiu

In the search of specific oxylipin fingerprint reflecting the development of endothelial dysfunction with the use of non...

Call: SONATA 17 , Panel: NZ5

Principal investigator: dr Agnieszka Róża Kij

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

The assessment of the susceptibility of the lung endothelium to infections with respiratory viruses and its involvement ...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr hab. Maciej Zygmunt Chałubiński

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Role of endothelial cells in development of post-inflammatory dilated cardiomyopathy

Call: PRELUDIUM BIS 3 , Panel: NZ5

Principal investigator: dr hab. Przemysław Jerzy Błyszczuk

Uniwersytet Jagielloński, Collegium Medicum

Multimodal approach for a comprehensive assessment of (dys)functional endothelial phenotype in isolated blood vessels

Call: SONATA 17 , Panel: ST4

Principal investigator: dr Marta Zofia Pacia

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Metabolic reprogramming in age-dependent endothelial dysfunction and vascular stiffness; novel mechanism of inflamm-agei...

Call: MAESTRO 13 , Panel: NZ4

Principal investigator: prof. Stefan Karol Chłopicki

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

PDMS-based specially designed microfluidic channel lined with primary endothelial cells: a novel tool for experimental p...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Stefano Rocchetti

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Assessment of the endothelial adherens junctions, neuronal damage and the fetal blood-brain barrier integrity in respons...

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: Natalia Barbara Misan

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

The role of rhinovirus in the limitation of infection of the human lung endothelium with low pathogenic coronavirus in t...

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: Mateusz Gawrysiak

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

The role of lactate dehydrogenase A in development of endothelial dysfunction in murine model of heart failure

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: Agnieszka Karolina Karaś

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Aging-associated, specific pathomechanisms of endothelial dysfunction in sepsis: pathway analysis and experimental thera...

Call: WEAVE-UNISONO , Panel: NZ7

Principal investigator: prof. Stefan Karol Chłopicki

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Vascular endothelium-supporting materials: Understanding the structural and physicochemical requirements

Call: OPUS 20 (LAP) , Panel: ST5

Principal investigator: prof. Tomasz Ciach

Politechnika Warszawska

Molecular background of microvascular complications in HNF1A-MODY patients: induced pluripotent stem cells as disease mo...

Call: SONATA BIS 10 , Panel: NZ3

Principal investigator: dr Neli Metodieva Kachamakova-Trojanowska

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Novel strategies for pharmacological modulation of platelet-derived microparticles - effects on endothelium

Call: PRELUDIUM 19 , Panel: NZ5

Principal investigator: Agnieszka Agata Pełesz

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

The proangiogenic functions of PIM kinases in plasma cell myeloma

Call: ETIUDA 8 , Panel: NZ5

Principal investigator: Filip Aleksander Garbicz

Instytut Hematologii i Transfuzjologii

Which patients with rheumatoid arthritis or axial spondyloarthritis without classical cardiovascular risk factors have m...

Call: PRELUDIUM 18 , Panel: NZ5

Principal investigator: Jarosław Łukasz Nowakowski

Uniwersytet Jagielloński, Collegium Medicum

Function and phenotype of liver sinusoidal endothelial cells (LSECs) and their role in liver dysfunction development in ...

Call: PRELUDIUM 18 , Panel: NZ5

Principal investigator: Kamila Wojnar-Lasoń

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Ecto-enzymes in interactions of vascular endothelium with blood circulating cells in physiology, pathology and therapy; ...

Call: SONATA 15 , Panel: NZ3

Principal investigator: dr Barbara Anna Kutryb-Zając

Gdański Uniwersytet Medyczny, Wydział Lekarski

Comparative evaluation of effects of tyrosine kinase inhibitors (TKIs) on endothelial function in vivo in mice

Call: PRELUDIUM 17 , Panel: NZ5

Principal investigator: Brygida Elżbieta Marczyk

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

The role of molecular composition of endothelial and pancreatic beta-cell extracellular vesicle in diabetic endothelial ...

Call: OPUS 17 , Panel: NZ3

Principal investigator: dr hab. Ewa Łucja Stępień

Uniwersytet Jagielloński

Cellular mechanisms and effects in vivo of selective lactate dehydrogenase A inhibitors in experimental models of mesoth...

Call: OPUS 16 , Panel: NZ7

Principal investigator: prof. Godefridus J Peters

Gdański Uniwersytet Medyczny, Wydział Lekarski

Glycocalyx damage - the first stage of pathomechanism of endothelial dysfunction; measurements using capillary electroph...

Call: PRELUDIUM 16 , Panel: NZ7

Principal investigator: dr Karolina Martyna Matyjaszczyk-Gwarda

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Ectosomal alpha-v beta-3 and alpha-v beta-5 as potential proangiogenic factors during melanoma progression

Call: PRELUDIUM 16 , Panel: NZ4

Principal investigator: dr Magdalena Surman

Uniwersytet Jagielloński, Wydział Biologii

Endothelial cells in the composition of hematopoietic niche: the versatile choir or specialized soloists?

Call: MAESTRO 10 , Panel: NZ3

Principal investigator: prof. Alicja Józkowicz

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

The assesment of endothelium considering role of endothelial progenitor cells and leukotrienes synthesis in patients wit...

Call: PRELUDIUM 14 , Panel: NZ5

Principal investigator: Agnieszka Wachsmann

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum

The role of Mcpip1 RNase in disrupted endothalial homeostasis accompanying nonalcoholic fatty liver disease.

Call: OPUS 14 , Panel: NZ5

Principal investigator: dr Jerzy Kotlinowski

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Peritoneal dialysis biocompatibility - peritoneal mesothelium - arterial endothelium

Call: OPUS 14 , Panel: NZ4

Principal investigator: prof. Andrzej Bręborowicz

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

Antithrombotic and antimicrobial activity of functionalized silver nanoparticles performed under in vitro, ex vivo condi...

Call: HARMONIA 9 , Panel: NZ7

Principal investigator: dr hab. Iwona Maria Inkielewicz-Stępniak

Gdański Uniwersytet Medyczny, Wydział Lekarski

The role of tumor secretable factors in modulation of endothelial senescence cells activity

Call: SONATA 13 , Panel: NZ7

Principal investigator: dr Wojciech Michał Ciszewski

Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

Determination of factors of reactive radial artery response to hyperaemia in assessment of hypertension and coronary art...

Call: OPUS 13 , Panel: ST7

Principal investigator: prof. Andrzej Nowicki

Instytut Podstawowych Problemów Techniki Polska Akademia Nauk

Rhinoviral infections of human vascular endothelium in the development of inflammation and airway remodeling in bronchia...

Call: OPUS 13 , Panel: NZ5

Principal investigator: dr hab. Maciej Zygmunt Chałubiński

Uniwersytet Medyczny w Łodzi, Wydział Lekarski, Międzywydziałowa Katedra Immunologii Klinicznej i Mikrobiologii

The role of reactive oxygen species (ROS) generated during a maximal exercise by endothelial NOX2 i NOX4 in the regulati...

Call: PRELUDIUM 13 , Panel: NZ4

Principal investigator: dr Kamil Przyborowski

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Endothelial inflammation studied in situ within functional blood vessels using Raman imaging, atomic force microscopy an...

Call: SONATINA 1 , Panel: ST4

Principal investigator: dr Marta Zofia Pacia

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

The role of LSD1 in the epigenetic regulation of transcription activity of NF-kappaB-dependent pro-inflammatory genes in...

Call: PRELUDIUM 12 , Panel: NZ3

Principal investigator: Martyna Paulina Wojtala

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Annexins as markers of vascular endothelium dysfunction in insulin resistance induced in vitro

Call: OPUS 12 , Panel: NZ3

Principal investigator: dr hab. Joanna Bandorowicz-Pikuła

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Editing of HNF1A gene in human induced pluripotent stem cells with CRISPR/Cas9 for disease modeling of endothelial (dys)...

Call: OPUS 12 , Panel: NZ1

Principal investigator: dr Neli Metodieva Kachamakova-Trojanowska

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Towards experimental pharmacology of endothelium in vivo based on multiparameter method of the assessment of vascular en...

Call: PRELUDIUM 12 , Panel: NZ5

Principal investigator: Anna Bar

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)