Projects funded by the NCN

Analysis of bee venom components for their anti-glioma activity in a cell and fish model (Danio reiro).

Call: PRELUDIUM BIS 2 , Panel: NZ3

Principal investigator: prof. Jacek Kurzepa

Uniwersytet Medyczny w Lublinie

Single cell multi-omics in defining how specific oncogenic alterations shape the immune microenvironment and responses t...

Call: OPUS 20 , Panel: NZ4

Principal investigator: prof. Bożena Kamińska-Kaczmarek

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

What does a viral infection smell like? Analysis of volatile organic compounds and the possibility of their detection on...

Call: SONATA 16 , Panel: NZ6

Principal investigator: dr Anna Karolina Matczuk

Uniwersytet Przyrodniczy we Wrocławiu

Towards re-definition of the mechanisms of entotic cell death; the role of HAX1 and SEPT7 in the regulation of entosis i...

Call: OPUS 20 , Panel: NZ3

Principal investigator: dr hab. Ewa Anna Grzybowska

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

A novel approach based on the optimized multidrug combination for glioblastoma treatment.

Call: SONATA 16 , Panel: NZ7

Principal investigator: prof. Małgorzata Kucińska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Phylogenetic models to infer cancer evolution

Call: SONATA 16 , Panel: ST6

Principal investigator: dr Jarosław Andrzej Paszek

Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

A cellular model for understanding gender differences in Leber's Hereditary Optic Neuropathy

Call: PRELUDIUM 2 , Panel: NZ3

Principal investigator: Agata Krystyna Kodroń

Uniwersytet Warszawski

A tissue engineering platform for precision cancer medicine and chemosensitivity testing in head and neck squamous cell ...

Call: OPUS 19 , Panel: NZ4

Principal investigator: prof. Matthias Nees

Uniwersytet Medyczny w Lublinie

The effect of methylated resveratrol analogue 3,4,4',5-tetramethoxystilbene (DMU-212) on secretion profile and different...

Call: PRELUDIUM 19 , Panel: NZ7

Principal investigator: Małgorzata Józkowiak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Modern nanoparticle and model organism - a toxic relation? Physiological and cellular causes of developmental disorders ...

Call: OPUS 19 , Panel: NZ7

Principal investigator: prof. Maria Jadwiga Augustyniak

UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

Development of an innovative method of preparing iPS cells for gene-cell therapy of hereditary diseases based on the Ost...

Call: PRELUDIUM 19 , Panel: NZ2

Principal investigator: dr Agnieszka Karolina Fus-Kujawa

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

Metabolic Chronopathology in Depression: Functional Astrocyte-Neuron Interactions in the Cellular Model of Glucocorticoi...

Call: POLS , Panel: NZ3

Principal investigator: dr Michał Wiesław Ślęzak

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

Characteristics of neurodevelopmental and behavioral changes in the tsc2vu242 zebrafish model of Tuberous Sclerosis Comp...

Call: ETIUDA 8 , Panel: NZ3

Principal investigator: Magdalena Anna Senderowska

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

A model of replication origin activation in response to replication stress and induction of premature mitoses, including...

Call: PRELUDIUM 18 , Panel: NZ3

Principal investigator: Marcelina Weronika Musiałek

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Exploring influence of inorganic cell microenvironment on NO signalling deregulation in age-related disorders. From mole...

Call: OPUS 18 , Panel: ST4

Principal investigator: prof. Grażyna Jolanta Stochel

Uniwersytet Jagielloński, Wydział Chemii

Targeting senescent brain cells to improve cognitive function in animal models of ageing and depression

Call: OPUS 18 , Panel: NZ4

Principal investigator: prof. Ewa Zofia Sikora

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Model for antimicrobial peptide-dependent evolution of plastids

Call: PRELUDIUM 18 , Panel: NZ8

Principal investigator: Filip Pietluch

Uniwersytet Wrocławski, Wydział Biotechnologii

Design and synthesis of proteolytically stable and cell permeable activators of human 20S proteasome and assessing their...

Call: PRELUDIUM BIS 1 , Panel: NZ7

Principal investigator: dr hab. Elżbieta - Jankowska

Uniwersytet Gdański, Wydział Chemii

Spatial network model of sequence and structure diversity of Human genome at a population scale

Call: PRELUDIUM BIS 1 , Panel: ST6

Principal investigator: prof. Dariusz Michał Plewczyński

Politechnika Warszawska, Wydział Matematyki i Nauk Informacyjnych

Transgenic mice with elevated basal level of calcium ions in neurons as a model of aged-induced neurodegeneration of spo...

Call: MAESTRO 1 , Panel: NZ3

Principal investigator: prof. Jacek Marceli Kuźnicki

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Protaminization of somatic cells nuclei as a model for nuclear reprogramming in somatic cell nuclear transfer.

Call: OPUS 18 , Panel: NZ3

Principal investigator: dr hab. Marta Czernik

Instytut Genetyki i Hodowli Zwierząt PAN

Effect of Embryonic Diapause on mitochondrial mutations inheritance in the mouse model of obesity.

Call: PRELUDIUM 18 , Panel: NZ3

Principal investigator: Łukasz Józef Gąsior

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Augmentation of nanoparticle uptake by accounting for tissue mechanics to enhance the effect of brain tumor treatment

Call: UWERTURA 4 , Panel: ST5

Principal investigator: dr Katarzyna Pogoda

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego PAN

Amotl1 mutant mice as a novel model of human psychiatric disorders associated with social dysfunctions

Call: OPUS 17 , Panel: NZ3

Principal investigator: dr hab. Tomasz Jacek Prószyński

Wrocławskie Centrum Badań EIT+ Sp. z o.o.

The role of utrophin in cardiomyopathy in Duchenne muscular dystrophy

Call: PRELUDIUM 17 , Panel: NZ3

Principal investigator: dr Kalina Andrysiak

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Nasal administration of probiotics - development of an allergic rhinitis in vitro model and the assessment of probiotic ...

Call: PRELUDIUM 17 , Panel: NZ7

Principal investigator: Marcelina Joanna Pyclik

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Analysis of the functions of isoforms of plant FEN1 and their phosphorylation using Arabidopsis thaliana as an experimen...

Call: OPUS 17 , Panel: NZ3

Principal investigator: dr hab. Wojciech Kazimierz Strzałka

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Linking abnormal Ca2+ signaling and the unfolded protein response with Huntington's disease pathology in both YAC128 mou...

Call: OPUS 17 , Panel: NZ3

Principal investigator: dr Magdalena Czeredys

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Poszukiwanie nowych mechanizmów neurodegeneracji w czasie rozwoju ataksji rdzeniowo-móżdżkowej typu 3 w mysim modelu kno...

Call: ETIUDA 7 , Panel: NZ3

Principal investigator: dr Kalina Katarzyna Wiatr

Instytut Chemii Bioorganicznej PAN

FIBROdrive - just a passenger or the driver? Investigating the mechanism of the cardiac fibroblast influence on heart ti...

Call: SONATA 14 , Panel: NZ3

Principal investigator: dr Tomasz Jan Kolanowski

Instytut Genetyki Człowieka PAN

Investigation of copper homeostasis disturbances in yeast model of rare neurodegenerative diseases associated with VPS13...

Call: PRELUDIUM 16 , Panel: NZ3

Principal investigator: Piotr Soczewka

Instytut Biochemii i Biofizyki PAN

Hypoxia-induced factors in altered oligodendrocyte differentiantion in the in vitro model of neonatal hypoxia-ischemia

Call: PRELUDIUM 16 , Panel: NZ3

Principal investigator: dr Justyna Janowska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Cytogenomic analysis of key aspects of nuclear genome organisation in the polyploid model grass Brachypodium hybridum an...

Call: OPUS 16 , Panel: NZ3

Principal investigator: prof. Robert Hasterok

UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

In vitro studies of polysaccharide interaction to revise existing models of plant cell wall structure

Call: OPUS 15 , Panel: NZ9

Principal investigator: dr hab. Monika Szymańska-Chargot

Instytut Agrofizyki im. Bohdana Dobrzańskiego PAN

Determination of mechanisms and critical molecular partners controlling the multidrug resistance proteins (P-gp and BCRP...

Call: OPUS 15 , Panel: NZ3

Principal investigator: dr hab. Marlena Godlewska

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO, Studium Kliniczno-Dydaktyczne

The role of circadian clock, Nrf2 transcription factor and haeme oxygenase in the regulation of innate immune responses....

Call: OPUS 15 , Panel: NZ3

Principal investigator: prof. Elżbieta Małgorzata Pyza

Uniwersytet Jagielloński, Wydział Biologii

Understanding the molecular basis of the regulation of activity of lysosome, a potential target of therapeutic intervent...

Call: OPUS 14 , Panel: NZ3

Principal investigator: prof. Magdalena Angelina Gabig-Cimińska

Uniwersytet Gdański, Wydział Biologii

Cell suspension culture of selected Viola L. species to study zinc and lead accumulation and cell tolerance to heavy met...

Call: PRELUDIUM 14 , Panel: NZ8

Principal investigator: dr Klaudia Małgorzata Sychta

Uniwersytet Jagielloński, Wydział Biologii

The role of intercellular communication in somatic embryogenesis induction and somatic embryo formation based on a model...

Call: PRELUDIUM 14 , Panel: NZ3

Principal investigator: Małgorzata Matylda Grzyb

Polska Akademia Nauk

Under the pressure of immunosupression. Mechanisms of loss and regeneration of rare T-cell subpopulations in a model of ...

Call: OPUS 14 , Panel: NZ6

Principal investigator: dr Magdalena Głowala-Kosińska

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Novel model for in vitro analyzing breast cancer, colorectal cancer and prostate cancer cells.

Call: OPUS 1 , Panel: NZ4

Principal investigator: prof. Piotr Rieske

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

How activation of the Mec1/Tel1 kinase (human ATR/ATM) pathway in response to the nuclear genome damage influences the s...

Call: OPUS 13 , Panel: NZ3

Principal investigator: dr Aneta Edyta Kaniak-Golik

Instytut Biochemii i Biofizyki PAN

Model of lipid nanoagregates transport by epitelial cells with additional steps of pharmacokinetic

Call: PRELUDIUM 13 , Panel: NZ7

Principal investigator: Kamila Szostak-Paluch

Politechnika Wrocławska

Mechanisms of cardiovascular complications in rheumatoid arthritis patients: induced pluripotent stem cell-derived cardi...

Call: OPUS 13 , Panel: NZ5

Principal investigator: dr Monika Biniecka

Kardio-Med Silesia Sp. z o.o.

Evaluation of nervous system cells homeostasis in the experimental in vitro model of cobalamin deficiency as an approach...

Call: PRELUDIUM 13 , Panel: NZ7

Principal investigator: Zuzanna Gertruda Rzepka

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Farmaceutycznych w Sosnowcu

Spontaneous senescence of ovarian cancer cells as an underestimated determinant of tumor progression: research on in vit...

Call: OPUS 13 , Panel: NZ3

Principal investigator: prof. Krzysztof Stefan Książek

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

Interaction of membrane-active peptides with model cell membrane and their role in a drug delivery system. Electrochemic...

Call: OPUS 12 , Panel: ST4

Principal investigator: dr Piotr Rafał Pięta

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Factors influencing effective transport of anticancer drugs through cell membranes studied on the example of the interac...

Call: SONATA 12 , Panel: ST4

Principal investigator: dr Dorota Matyszewska

Uniwersytet Warszawski, Wydział Chemii

The new role of KAEA, the highly conserved subunit of the KEOPS/EKC complex, in the model filamentous fungus Aspergillus...

Call: PRELUDIUM 12 , Panel: NZ3

Principal investigator: Joanna Danuta Gawlik

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Understanding of the functioning of mitochondrial ATP synthase by studying in yeast the phenotype of human pathology rel...

Call: OPUS 12 , Panel: NZ3

Principal investigator: dr hab. Róża Kucharczyk

Instytut Biochemii i Biofizyki PAN