Projects funded by the NCN

The contribution of the connection between 3' and 5' termini via cap binding proteins to snoRNA processing in S. cerevis...

Call: PRELUDIUM 1 , Panel: NZ1

Principal investigator: Sylwia Szczepaniak

Uniwersytet Warszawski, Wydział Biologii

New nucleotide analogs containing triazole within oligophosphate bridge as mimics of the 5' end of mRNA - synthesis, pro...

Call: PRELUDIUM 9 , Panel: ST5

Principal investigator: Sylwia Ciechanowicz

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Contribution of 5'-end RNA quality control to cellular processes in Arabidopsis thaliana.

Call: OPUS 8 , Panel: NZ2

Principal investigator: prof. Joanna Kufel

Uniwersytet Warszawski, Wydział Biologii

Synthesis, biological and biophysical evaluation of mRNA cap-peptide conjugates for targeted delivery of cap analogues t...

Call: OPUS 6 , Panel: ST5

Principal investigator: dr hab. Marzena Jankowska-Anyszka

Uniwersytet Warszawski, Wydział Chemii

New methods for mRNA 5' end labeling and examples of their application in studies on RNA metabolism and searching for in...

Call: OPUS 5 , Panel: ST5

Principal investigator: dr hab. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Designing mRNA transcripts resistant to enzymatic cap hydrolysis applicable for anti-cancer vaccines; multiplexed bioche...

Call: MAESTRO 4 , Panel: NZ1

Principal investigator: prof. Edward Darżynkiewicz

Uniwersytet Warszawski, Centrum Nowych Technologii

Members of eIF4E protein family, their affinities towards 5' mRNA cap and protein binding partners: an interdisciplinary...

Call: OPUS 4 , Panel: NZ1

Principal investigator: prof. Edward Darżynkiewicz

Uniwersytet Warszawski, Wydział Fizyki

New reagents and methods in synthesis of modified nucleotides and their application for preparation biochemical tools an...

Call: SONATA BIS 1 , Panel: ST5

Principal investigator: dr hab. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Synthesis of mononucleotide N2,N2,7-trimethylguanosine cap analogues as translation inhibitors in Ascaris suum

Call: PRELUDIUM 3 , Panel: ST5

Principal investigator: dr Karolina Piecyk

Uniwersytet Warszawski, Wydział Chemii

Conjugates of cap analogs with nanomaterials and biomolecules with potential applications in pharmacology or diagnostics

Call: SONATA 1 , Panel: ST5

Principal investigator: dr Joanna Kowalska

Uniwersytet Warszawski, Wydział Fizyki

Macro, mezo and microeconomic efficiency of supporting investment in agricultural holdings with use of the European Unio...

Call: OPUS 1 , Panel: HS4

Principal investigator: dr hab. Wawrzyniec Czubak

Uniwersytet Przyrodniczy w Poznaniu, Wydział Ekonomiczno-Społeczny

Deciphering how viral epitranscriptome shapes host immune response.

Call: SONATA BIS 11 , Panel: NZ1

Principal investigator: dr Paweł Sikorski

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Designing modified mRNAs as vaccines and therapeutic protein carriers. Studies on their immunogenicity in the context of...

Call: OPUS 17 , Panel: NZ1

Principal investigator: prof. Edward Darżynkiewicz

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Gold and silver nanoparticles as carriers for delivery of 5' end mRNA cap analogues with potential therapeutical applica...

Call: OPUS 16 , Panel: ST5

Principal investigator: dr hab. Marzena Jankowska-Anyszka

Uniwersytet Warszawski, Wydział Chemii

Synthesis and characterization of new molecular probes for monitoring activity of enzymes associated with RNA decapping ...

Call: OPUS 16 , Panel: ST5

Principal investigator: dr hab. Joanna Kowalska

Uniwersytet Warszawski, Wydział Fizyki

Towards understanding the cellular fate of exogenously delivered mRNA

Call: SONATA 14 , Panel: NZ1

Principal investigator: dr hab. Paweł Sikorski

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Comprehensive research on enzymatic hydrolysis of native and chemically modified 5' RNA structures by Nudix protein fami...

Call: OPUS 14 , Panel: NZ1

Principal investigator: prof. Edward Darżynkiewicz

Uniwersytet Warszawski, Wydział Fizyki

Synthesis of trimethyl cap analogs modified with molecular rotors and their application in nuclear transport studies

Call: SONATA 13 , Panel: ST5

Principal investigator: dr Błażej Wojtczak

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Investigating the biological role of 5' nucleotidases cN-IIIA and cN-IIIB in mRNA degradation and their terapeutic signi...

Call: SONATINA 1 , Panel: NZ1

Principal investigator: dr Dorota Kubacka

Uniwersytet Warszawski, Wydział Fizyki

Development of HTS method based on fluorescently labelled guanosine analogues: novel route for RNA (guanosine-N7)-methyl...

Call: PRELUDIUM 12 , Panel: ST4

Principal investigator: Renata Kasprzyk

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Development of HTS method based on fluorescently labelled guanosine analogues: novel route for RNA (guanosine-N7)-methyl...

Call: PRELUDIUM 12 , Panel: ST4

Principal investigator: Renata Kasprzyk

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Pro-nucleotides based on mRNA cap structure - synthesis, biological and biophysical evaluation

Call: SONATA 11 , Panel: ST5

Principal investigator: dr Karolina Piecyk

Uniwersytet Warszawski, Wydział Chemii

Determination of structure and specificity of the RNA cap-modifying enzyme CMTr2.

Call: SONATA 10 , Panel: NZ1

Principal investigator: dr Veronika Fluegel

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Regulation of the human cap methyltransferase CMTr1 by an RNA helicase

Call: PRELUDIUM 10 , Panel: NZ1

Principal investigator: Magdalena Zielińska

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Synthesis and evaluation of a novel toolkit for biology and biotechnology based on adenine nucleotides analogs

Call: SONATA BIS 5 , Panel: ST5

Principal investigator: dr hab. Joanna Kowalska

Uniwersytet Warszawski, Wydział Fizyki