Projects funded by the NCN

Studies on receptor layers formed by DNA and RNA aptamers in respect of their potential application in biosensors for de...

Call: PRELUDIUM 8 , Panel: ST4

Principal investigator: dr Marta Jarczewska

POLITECHNIKA WARSZAWSKA

New high dimensional NMR spectroscopy experiments for three dimensional structure elucidation of nucleic acids.

Call: PRELUDIUM 6 , Panel: ST4

Principal investigator: Saurabh Saxena

Uniwersytet Warszawski, Wydział Chemii

Thermodynamic insights into design of functionally optimized modified siRNAs and their experimental verification.

Call: SONATA BIS 3 , Panel: NZ1

Principal investigator: dr hab. Anna Pasternak

Instytut Chemii Bioorganicznej PAN

New methods for mRNA 5' end labeling and examples of their application in studies on RNA metabolism and searching for in...

Call: OPUS 5 , Panel: ST5

Principal investigator: dr hab. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Interactions of peptide nucleic acids with biologically relevant RNA motifs

Call: OPUS 3 , Panel: NZ1

Principal investigator: dr hab. Joanna Trylska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

New methods for the determination of RNA secondary structure, tools towards studies biological activities of RNAs

Call: OPUS 2 , Panel: NZ1

Principal investigator: prof. Ryszard Kierzek

INSTYTUT CHEMII BIOORGANICZNEJ PAN

Antisense oligonucleotides as tools specifically binding viral G-quadruplexes and their experimental verification

Call: OPUS 25 , Panel: ST4

Principal investigator: dr Marta Szabat

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Deciphering RNA self-replication with quantum chemistry and machine learning.

Call: SONATA BIS 12 , Panel: ST4

Principal investigator: dr Rafał Szabla

Politechnika Wrocławska

Thermodynamics of modified RNAs. Impact of RNA modifications on structure and function of natural RNA and vaccine-type i...

Call: OPUS 23 , Panel: ST4

Principal investigator: prof. Ryszard Kierzek

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

High-throughput droplet microfluidics for dissecting cellular interactions.

Call: SONATA 17 , Panel: ST4

Principal investigator: dr Tomasz Kamiński

Uniwersytet Warszawski, Wydział Biologii

Synthesis and structural/biophysical studies of model mRNA/mt-tRNA oligomers to evaluate the role of modified nucleoside...

Call: OPUS 22 , Panel: ST4

Principal investigator: dr hab. Grażyna Leszczyńska

Politechnika Łódzka

Antiviral strategies targeting RNA: Triplex forming peptide nucleic acids (PNA) and their small molecule conjugates spec...

Call: OPUS 21 , Panel: NZ1

Principal investigator: prof. Elżbieta Kierzek

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Chiroptical properties of proteins and their complexes (CRISPR/Cas-RNA), and their relationship to biological activity

Call: SONATINA 5 , Panel: ST4

Principal investigator: dr Monika Hałat

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Biotechnologii i Ogrodnictwa

High throughput microfluidic system for fast determination of the equilibrium constant for biomolecular complexes: appli...

Call: PRELUDIUM BIS 2 , Panel: ST4

Principal investigator: prof. Robert Hołyst

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Anti-cancer strategy based on the induced G-quadruplex formation. Structural and biological properties of ligand-RNA/mRN...

Call: SONATA 16 , Panel: ST4

Principal investigator: dr Dorota Gudanis

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Photodamage and self-healing of primordial forms of DNA and RNA.

Call: OPUS 19 , Panel: ST4

Principal investigator: dr Rafał Szabla

Politechnika Wrocławska

Designing modified mRNAs as vaccines and therapeutic protein carriers. Studies on their immunogenicity in the context of...

Call: OPUS 17 , Panel: NZ1

Principal investigator: prof. Edward Darżynkiewicz

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Thermodynamic parameters and rules towards the determination of RNA folding in in vivo-like conditions. RNA folding pred...

Call: OPUS 17 , Panel: ST4

Principal investigator: prof. Ryszard Kierzek

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Development of HTS method based on fluorescently labelled guanosine analogues: novel route for RNA (guanosine-N7)-methyl...

Call: PRELUDIUM 12 , Panel: ST4

Principal investigator: Renata Kasprzyk

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Application of LCMS to quantitative analysis of composition of in vitro transcribed RNAs containing chemically modified ...

Call: PRELUDIUM 12 , Panel: ST4

Principal investigator: Dominika Strzelecka

Uniwersytet Warszawski, Wydział Fizyki

Determination of the influence of 5' end of RNA modifications and nucleotide or amino acid sequence on the electrostatic...

Call: PRELUDIUM 11 , Panel: ST4

Principal investigator: Urszula Budniak

Uniwersytet Warszawski, Wydział Chemii

Chromatographic determination of nucleic acids (DNA, RNA) and their constituents (nucleosides, nucleotides, oligonuceoti...

Call: SONATA 1 , Panel: ST4

Principal investigator: dr Sylwia Studzińska

UNIWERSYTET MIKOŁAJA KOPERNIKA, Wydział Chemii, Katedra Chemii Środowiska i Bioanalityki

Modeling 3D structures and dynamics of RNA complexes with metal ions, with particular emphasis on the formation of non-c...

Call: SONATA 9 , Panel: NZ1

Principal investigator: dr Dorota Niedziałek

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk