Projects funded by the NCN

Altered interaction between NMDA receptor subunits and their scaffolding proteins as a critical step to control drug see...

Call: OPUS 9 , Panel: NZ7

Principal investigator: prof. Małgorzata Filip

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Abeta 4-x peptides as copper binding molecules resistant to chelating drugs, promoting the formation of amyloid oligomer...

Call: OPUS 8 , Panel: ST5

Principal investigator: prof. Wojciech Bal

Instytut Biochemii i Biofizyki PAN

Identyfication of antioxidant peptides obtained from proteins selected edible insects species.

Call: PRELUDIUM 8 , Panel: NZ9

Principal investigator: Ewelina Zielińska

Uniwersytet Przyrodniczy w Lublinie, Wydział Nauk o Żywności i Biotechnologii

Genetic basis of cyclic peptide biosynthesis by entomopathogenic and phytopathogenic Hypocreales fungi

Call: OPUS 8 , Panel: NZ9

Principal investigator: prof. Łukasz Stępień

Instytut Genetyki Roślin PAN

Dynamic peptide-resorcinarene capsules synthesized by classical and mechanochemical methods

Call: PRELUDIUM 8 , Panel: ST5

Principal investigator: Hanna Jędrzejewska

Instytut Chemii Organicznej PAN

Determination of peptide lung cancer biomarkers by novel analytical platforms with imprinted polymers as selective recog...

Call: OPUS 8 , Panel: ST4

Principal investigator: dr Krzysztof Noworyta

Instytut Chemii Fizycznej PAN

Engineering disulfide bridges in human beta-defensin 3 for novel antibacterial and antifungal activities

Call: SONATA 8 , Panel: ST5

Principal investigator: dr Aleksandra Walewska

Uniwersytet Gdański, Wydział Chemii

Novel angiotensin peptides - formation and role in adipose tissue in rat model of obesity and insulin resistance

Call: HARMONIA 1 , Panel: NZ4

Principal investigator: prof. Rafał Olszanecki

Uniwersytet Jagielloński- Collegium Medicum, Wydział Lekarski

The ability of Lactobacillus helveticus strains to a production of biologically active peptides - an antioxidative prope...

Call: PRELUDIUM 8 , Panel: NZ9

Principal investigator: Katarzyna Skrzypczak

Uniwersytet Przyrodniczy w Lublinie, Wydział Nauk o Żywności i Biotechnologii

Synthesis and tandem mass spectrometry examination of new ionization tags based on thiazolidinecarboxylic acid and oxazo...

Call: PRELUDIUM 8 , Panel: ST5

Principal investigator: Bartosz Setner

Uniwersytet Wrocławski, Wydział Chemii

The molecular mechanism of activity of alphaherpesvirus-encoded key immune evasion proteins

Call: SONATA BIS 4 , Panel: NZ6

Principal investigator: dr Andrea Lipińska

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Determination of the exact structure of the complex (complexes) of AB1-16 peptide with Pd(II) ions using nuclear magneti...

Call: PRELUDIUM 7 , Panel: ST5

Principal investigator: Mariusz Mital

Instytut Biochemii i Biofizyki PAN

Can Fusobacterium nucleatum adhesion proteins increase prooxidative activity of iron and copper ions?

Call: OPUS 7 , Panel: ST5

Principal investigator: dr Kamila Stokowa-Sołtys

Uniwersytet Wrocławski, Wydział Chemii

The role of the factors involved in the brain glucose metabolism in the model of obesity and depression comorbidity

Call: OPUS 7 , Panel: NZ7

Principal investigator: prof. Bogusława Budziszewska

Instytut Farmakologii PAN

New methodologies of solid state NMR spectroscopy in the structural studies and dynamics of selected proteins and peptid...

Call: OPUS 7 , Panel: ST4

Principal investigator: prof. Marek Potrzebowski

Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

The role of homing peptides linked to bacteriophages in treating prostate and lung infection

Call: PRELUDIUM 7 , Panel: NZ6

Principal investigator: dr Katarzyna Hodyra-Stefaniak

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

Impact of opioid-neurotensin chimera (PK20) on inflammation in murine model of contact sensitivity reaction and non-atho...

Call: OPUS 7 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Kaczyńska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Design, chemical synthesis and biological activity of inhibitors of matriptase-2.

Call: PRELUDIUM 7 , Panel: ST5

Principal investigator: Agata Gitlin-Domagalska

Uniwersytet Gdański, Wydział Chemii

Antihypertensive properties of rapeseed-derived peptides in rats. Potential role of the new mechanisms of ang I conversi...

Call: OPUS 1 , Panel: NZ4

Principal investigator: prof. Elżbieta Kompanowska-Jezierska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

The role of antimicrobial protein-chemerin in skin pathophysiology.

Call: SYMFONIA 2 , Panel: NZ6

Principal investigator: prof. Joanna Cichy

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Metabolism of angiotensins in human placenta in preeclampsia. Ex vivo assessment using liquid chromatography/ mass spect...

Call: PRELUDIUM 6 , Panel: NZ4

Principal investigator: Dominika Stettner-Kołodziejska

Uniwersytet Jagielloński Collegium Medicum, Collegium Medicum, Wydział Lekarski

Photo-induced oxidizing reactions of peptides and proteins containing the thioether group. Mechanisms of reactions - for...

Call: OPUS 6 , Panel: ST4

Principal investigator: dr Piotr Filipiak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Application of macrocycles formed by substituted trithiocyanuric acid as template for self-assembly of peptide chains

Call: PRELUDIUM 6 , Panel: ST5

Principal investigator: dr Marta Cal

Uniwersytet Wrocławski, Wydział Chemii

Polymeric stationary phases containing gold and silver nanoparticles in analytics of biologically active compounds

Call: PRELUDIUM 6 , Panel: ST4

Principal investigator: Damian Grzywiński

Uniwersytet Mikołaja Kopernika, Wydział Chemii

Synthesis and structural study of modified porphyrinoids

Call: PRELUDIUM 6 , Panel: ST5

Principal investigator: Justyna Śniechowska

Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

Nickel oxides and metallic nickel as nickel(II) ion sources for nicklel(II)-assisted hydrolysis of peptide bond

Call: PRELUDIUM 6 , Panel: NZ1

Principal investigator: Nina Wezynfeld

Instytut Biochemii i Biofizyki PAN

Peptidyl arginine deiminase, a novel virulence factor of Porphyromonas gingivalis

Call: OPUS 1 , Panel: NZ6

Principal investigator: prof. Jan Potempa

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Exploring the possibility of quantitative analysis of skeletal muscle proteins after thermal treatment based on selected...

Call: SONATA 6 , Panel: NZ9

Principal investigator: dr Magdalena Montowska

Uniwersytet Przyrodniczy w Poznaniu, Wydział Nauk o Żywności i Żywieniu

Toll pathways and microRNA in regulating the immune system of the honey bee Apis mellifera carnica in response to infect...

Call: PRELUDIUM 6 , Panel: NZ9

Principal investigator: dr Ewa Zaobidna

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

A development of a method of micro-scale synthesis of peptides labelled with stable isotopes for quantitative proteomics

Call: PRELUDIUM 6 , Panel: ST4

Principal investigator: Maciej Modzel

Uniwersytet Wrocławski, Wydział Chemii

Synthesis, biological and biophysical evaluation of mRNA cap-peptide conjugates for targeted delivery of cap analogues t...

Call: OPUS 6 , Panel: ST5

Principal investigator: dr hab. Marzena Jankowska-Anyszka

Uniwersytet Warszawski, Wydział Chemii

Novel peptide inhibitors of dipeptidyl peptidase IV (DPP IV) as novel approach for diabetes type 2 and inflammatory bowe...

Call: PRELUDIUM 6 , Panel: NZ7

Principal investigator: Maciej Sałaga

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Synthesis, physico-chemical and biological studies on macromolecular carriers of antimicrobial peptides

Call: PRELUDIUM 6 , Panel: NZ7

Principal investigator: Urszula Piotrowska

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Conjugates of prion protein with dendrimers as inhibitors of Abeta peptide amyloidogenesis and cytotoxicity of potential...

Call: HARMONIA 5 , Panel: NZ4

Principal investigator: dr hab. Krzysztof Nieznański

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

The key mechanizm for the development of allergy to nickel: A role of the filaggrin fragments, a potential carrier prote...

Call: PRELUDIUM 5 , Panel: NZ6

Principal investigator: Ewa Podobas

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Alpha factor of S. cerevisiae yeast: formation of copper and zinc complexes and their biological activity

Call: OPUS 5 , Panel: ST5

Principal investigator: prof. Wojciech Bal

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Synthesis and pharmacological characterization of novel cyclic opioid peptide analogs incorporating fluoro amino acids.

Call: PRELUDIUM 5 , Panel: NZ7

Principal investigator: dr Justyna Piekielna-Ciesielska

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Studies on the metal ions impact on the structure and functions of peptidic inhibitors of aggregation of proteins involv...

Call: OPUS 1 , Panel: ST5

Principal investigator: dr Marek Łuczkowski

Uniwersytet Wrocławski, Wydział Chemii

Synthesis and fragmentation of peptides conjugated with betaine derivatives - a search for isobaric markers for quantita...

Call: OPUS 5 , Panel: ST4

Principal investigator: prof. Zbigniew Szewczuk

Uniwersytet Wrocławski, Wydział Chemii

Fungal alpha-1,3-glucan as an elicitor of insect innate immune response

Call: PRELUDIUM 5 , Panel: NZ6

Principal investigator: Sylwia Stączek

Uniwersytet Marii Curie-Skłodowskiej, Wydział Biologii i Biotechnologii

Functionalization of photosensitizing compounds with antimicrobial peptides to enhance photoantimicrobial chemotherapy o...

Call: OPUS 5 , Panel: NZ7

Principal investigator: dr Joanna Nakonieczna

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Identification of beetles neuropeptides with homology to vertebrate peptides

Call: SONATA 5 , Panel: NZ3

Principal investigator: dr Paweł Marciniak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Susceptibility of human antimicrobial peptides to the action of aspartic proteases secreted by pathogenic yeast Candida ...

Call: PRELUDIUM 5 , Panel: NZ1

Principal investigator: Oliwia Bocheńska

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Morita-Baylis-Hillman adducts as substrates in the synthesis of biologically active organophosphorus compounds

Call: OPUS 5 , Panel: ST5

Principal investigator: dr hab. Artur Mucha

Politechnika Wrocławska, Wydział Chemiczny

The influence of glucagon-like peptied-1 receptor agaonists on regulation of coticotropin-releasing hormone gene promote...

Call: PRELUDIUM 4 , Panel: NZ7

Principal investigator: Jan Detka

Instytut Farmakologii PAN

Synthetic cysteine peptides as molecular layers for studies of interactions between copper ions and beta-amyloid

Call: SONATA 4 , Panel: ST4

Principal investigator: dr Urszula Wawrzyniak

Politechnika Warszawska, Wydział Chemiczny

Significance of peptides citrullinated by peptidylarginine deiminase from Porphyromonas gingivalis in periodontitis.

Call: OPUS 4 , Panel: NZ6

Principal investigator: dr Katarzyna Gawron

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Design, chemical synthesis and enzymatic evaluation of peptidic substrates and inhibitors of cathepsin C

Call: PRELUDIUM 4 , Panel: ST5

Principal investigator: dr Monika Łęgowska

Uniwersytet Gdański, Wydział Chemii

Fluorescent substrates of neutrophil proteinases: design, chemical synthesis , selection by the combinatorial chemistry ...

Call: PRELUDIUM 4 , Panel: ST5

Principal investigator: dr Jadwiga Popow - Stellmaszyk

Uniwersytet Gdański, Wydział Chemii

Synthesis and biological studies of conjugates formed by peptide dendrimers and natural polyphenols and their analogs

Call: OPUS 4 , Panel: ST5

Principal investigator: prof. Zofia Lipkowska

Instytut Chemii Organicznej PAN