Projects funded by the NCN
Retro-inverso modification of zinc(II)–GLP-1 receptor agonist complexes – from bioinorganic chemistry to animal studies
2023/51/B/ST5/01098
Keywords:
antidiabetic peptides metal-peptide complexes peptidomimetics thermodynamics potentiometry coordination chemistry bioinorganic chemistry pharmacodynamic and pharmacokinetic properties
Descriptors:
- ST5_10:
- ST5_15:
- NZ7_14:
Panel:
ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering
Host institution :
Uniwersytet Wrocławski, Wydział Chemii
woj. dolnośląskie
Principal investigator (from the host institution):
dr hab. Magdalena Alina Rowińska-Żyrek
Number of co-investigators in the project: 6
Call: OPUS 26 - announced on 2023-09-18
Amount awarded: 3 313 794 PLN
Project start date (Y-m-d): 2024-07-26
Project end date (Y-m-d): 2028-07-25
Project duration:: 48 months (the same as in the proposal)
Project status: Pending project
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Metal-Induced Amide Deprotonation and Binding Typical for Cu(II), Not Possible for Zn(II) and Fe(II)Authors:Leveraro Silvia, Dzyhovskyi Valentyn, Garstka Kinga, Szebesczyk Agnieszka, Zobi Fabio, Bellotti Denise, Stokowa-Sołtys Kamila, Remelli Maurizio, Rowińska-Żyrek MagdalenaAcademic press:Inorganic Chemistry (rok: 2025, tom: 64, strony: 6751-6760), Wydawca: American Chemical SocietyStatus:PublishedDOI:10.1021/acs.inorgchem.5c00672 - link to the publication