Projects funded by the NCN

Allosteric and allosteric-orthosteric bitopic ligands of histamine receptor H4 as a way to increase selectivity and bias...

Call: OPUS 23 , Panel: NZ7

Principal investigator: prof. Sławomir Hubert Filipek

Uniwersytet Warszawski, Wydział Chemii

Bacterial microdomain modeling for selected antimicrobial compounds interactions.

Call: PRELUDIUM 21 , Panel: NZ9

Principal investigator: dr Mateusz Igor Rzycki

Politechnika Wrocławska

Biodiversity of bacteriophages: unusual DNA polymerases as exampels of surprising molecular diversity.

Call: OPUS 23 , Panel: NZ1

Principal investigator: prof. Alicja Beata Węgrzyn

Uniwersytet Gdański

Structural studies of herpesvirus proteins involved in DNA replication

Call: OPUS 23 , Panel: NZ1

Principal investigator: dr Małgorzata Maria Figiel

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

A rare Single Nucleotide Polymorphism in human WDR61 used to identify a novel complex associated with SF3A/B component o...

Call: OPUS 23 , Panel: NZ1

Principal investigator: dr Agnieszka Irena Tudek

Instytut Biochemii i Biofizyki PAN

Small worlds: uncovering local and medium scale invertebrate diversity and phylogeography with environmental DNA

Call: OPUS 23 , Panel: NZ8

Principal investigator: dr Alejandro Lopez Lopez

Uniwersytet Jagielloński, Wydział Biologii

How ionizing radiation influence the functioning of the oxidative stress andDNA repair systems of glacial microbial comm...

Call: PRELUDIUM 21 , Panel: NZ8

Principal investigator: dr Jakub Andrzej Buda

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Multi-omics characterization and detection of the emerging phytopathogenic fungus – Pilidium lythri

Call: PRELUDIUM 21 , Panel: NZ9

Principal investigator: dr Dominika Grażyna Siegieda

Instytut Agrofizyki im. Bohdana Dobrzańskiego PAN

The effects of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors on changes in selected epigenetic mechan...

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Agnieszka Magdalena Woźniak

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Novel anti-Stokes lanthanide-doped nanoparticles and multicolor FRET mechanisms for single-molecule DNA sequencing (Lant...

Call: WEAVE-UNISONO , Panel: ST5

Principal investigator: prof. Artur Bednarkiewicz

Instytut Niskich Temperatur i Badań Strukturalnych im. Włodzimierza Trzebiatowskiego PAN

Significance of discordant methylation phenomenon in cell physiology

Call: OPUS 22 , Panel: NZ2

Principal investigator: dr hab. Tomasz Kazimierz Wojdacz

Pomorski Uniwersytet Medyczny w Szczecinie

The role of the methylation of the progesterone receptor isoforms A and B promoters in the regulation of bovine corpus l...

Call: OPUS 22 , Panel: NZ9

Principal investigator: dr hab. Robert Jarosław Rękawiecki

Instytut Rozrodu Zwierząt i Badań Żywności PAN

cfDNA methylome analysis in Hodgkin lymphoma patients

Call: SONATA 17 , Panel: NZ5

Principal investigator: dr Kinga Katarzyna Bednarek

Instytut Genetyki Człowieka PAN

The role of transposable elements and epigenetic regulation of gene expression in Medicago truncatula root nodules devel...

Call: PRELUDIUM BIS 3 , Panel: NZ2

Principal investigator: dr hab. Agnieszka Jowita Żmieńko

Instytut Chemii Bioorganicznej PAN

Polyphosphate and DNA as scaffolds for proteins during stress and normal growth

Call: OPUS 22 , Panel: NZ1

Principal investigator: prof. Igor Piotr Konieczny

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Radiosensitization by the combined use of modified nucleosides and inhibitors of DNA repair to improve the efficacy of r...

Call: SONATA 17 , Panel: ST4

Principal investigator: dr Magdalena Danuta Zdrowowicz-Żamojć

Uniwersytet Gdański, Wydział Chemii

Determining the natural function of short oligodeoxynucleotides to enable their use for precise and efficient genome edi...

Call: OPUS 22 , Panel: NZ9

Principal investigator: dr hab. Magdalena Ewa Żuk

Uniwersytet Wrocławski, Wydział Biotechnologii

A framework for de novo modeling of RNA structures using restraints derived from experimental data

Call: SONATA 17 , Panel: NZ1

Principal investigator: dr Sunandan Mukherjee

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Unraveling the chronological, geographical, and taphonomic complexities of theoccurrence of the woolly rhinoceros in the...

Call: OPUS 22 , Panel: ST10

Principal investigator: dr hab. Kamilla Anna Pawłowska

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Nauk Geograficznych i Geologicznych

Epigenetic traces of anhydrobiosis: a study of DNA and protein modifications through tardigrade generations

Call: PRELUDIUM BIS 3 , Panel: NZ4

Principal investigator: dr hab. Robert Nawrot

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Reversible modulation of G-quadruplex functions using photoresponsive ligands - in vitro and cellular studies

Call: SONATA 17 , Panel: ST4

Principal investigator: dr Marta Maria Dudek

Politechnika Wrocławska

The role of BRM and SYD ATPases interplay with MINU1 and MINU2 ATPases in organ-specific alternative RNA processing regu...

Call: SONATA 17 , Panel: NZ2

Principal investigator: dr Szymon Kubala

Instytut Biochemii i Biofizyki PAN

Evaluation of the brain microbiome and proteome as well as the role of fecal microbiota transplantation (FMT) in schizop...

Call: SONATA 17 , Panel: NZ5

Principal investigator: dr Dominika Salamon

Uniwersytet Jagielloński, Collegium Medicum

Mitochondrial DNA alterations in malignant tumours of spleen in dogs - assessment of their role and diagnostic value

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: dr Angelika Tkaczyk-Wlizło

Uniwersytet Przyrodniczy w Lublinie

Dynamics of non-tidal sea bed in the remote foreshore

Call: OPUS 21 , Panel: ST8

Principal investigator: prof. Rafał Ostrowski

Instytut Budownictwa Wodnego PAN

Mechanisms of cell cycle regulation in Pseudomonas aeruginosa and theirrole in adaptation capacity of the dangerous path...

Call: PRELUDIUM 20 , Panel: NZ2

Principal investigator: Aneta Urszula Szulc

Uniwersytet Gdański, Wydział Biologii

Optimal-transport based algorithms for Mass Spectrometry and NMR

Call: OPUS 21 , Panel: ST6

Principal investigator: prof. Anna Barbara Gambin

Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

Influence of oral anticoagulants, rivaroxaban and dabigatran on the development and course of ischemia/reperfusion-induc...

Call: OPUS 21 , Panel: NZ5

Principal investigator: prof. Piotr Ceranowicz

Uniwersytet Jagielloński, Collegium Medicum

Oxidative, hemolytic or genotoxic stress - which one triggers a type I interferon response in heme oxygenase-1 deficient...

Call: PRELUDIUM 20 , Panel: NZ3

Principal investigator: Patryk Dominik Chudy

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Mechanisms regulating the cellular level of the most mutagenic human DNApolymerase - the role of p300 acetyltransferase ...

Call: OPUS 21 , Panel: NZ1

Principal investigator: dr hab. Justyna McIntyre

Instytut Biochemii i Biofizyki PAN

The genome-wide DNA methylation pattern alterations in the peripheral whole blood cells' in Graves' disease patients and...

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: Mikołaj Artur Radziszewski

Warszawski Uniwersytet Medyczny

Novel factors involved in cell cycle control after DNA damage.

Call: OPUS 21 , Panel: NZ1

Principal investigator: dr Michał Zbigniew Malewicz

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

Functional divergence of Flowering Locus T gene duplicates in photoperiod and vernalization control of flowering inducti...

Call: OPUS 21 , Panel: NZ9

Principal investigator: dr hab. Michał Piotr Książkiewicz

Instytut Genetyki Roślin PAN

Close Encounters of the Third Kind: what happens when ribonuclease Dicer encounters in the cell RNA and DNA adopting G-q...

Call: OPUS 21 , Panel: NZ2

Principal investigator: dr hab. Anna Maria Kurzyńska-Kokorniak

Instytut Chemii Bioorganicznej PAN

Role of extracellular DNA, generated during communal wastes treatment, indissemination of virulence and antibiotic resis...

Call: OPUS 21 , Panel: NZ9

Principal investigator: prof. Łukasz Jacek Dziewit

Uniwersytet Warszawski, Wydział Biologii

A novel probabilistic model for cell type identification in spatial transcriptomics and single-cell RNA sequencing data

Call: PRELUDIUM 20 , Panel: ST6

Principal investigator: Agnieszka Izabela Geras

Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

Testing the hypothesis of mitochondrial DNA evolution using hybrid zone of forest tree species and de novo sequence geno...

Call: PRELUDIUM 20 , Panel: NZ8

Principal investigator: Bartosz Łabiszak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Investigation of DNA repair mechanisms in DRPLA model using CRISPR-Cas system

Call: PRELUDIUM 20 , Panel: NZ2

Principal investigator: dr Magdalena Dąbrowska

Instytut Chemii Bioorganicznej PAN

Insight into the mechanism of the toxic effect of copper on Phytophthora infestans - the causative agent of potato late ...

Call: PRELUDIUM 20 , Panel: NZ9

Principal investigator: Joanna Maria Gajewska

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Thrombin binding aptamer with expanded chemical diversity as potential anticoagulant and anticancer agent

Call: OPUS 21 , Panel: NZ7

Principal investigator: dr Weronika Paulina Kotkowiak

Instytut Chemii Bioorganicznej PAN

MLK4 signaling in DNA damage response and cancer therapy

Call: PRELUDIUM 20 , Panel: NZ3

Principal investigator: Dawid Grzegorz Mehlich

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Methods for the similarity analysis of low complexity regions in proteins

Call: PRELUDIUM 20 , Panel: ST6

Principal investigator: dr Patryk Paweł Jarnot

Politechnika Śląska, Wydział Automatyki, Elektroniki i Informatyki

Genetic and epigenetic fundamentals of cerebral vasospasm after aneurysmal subarachnoid hemorrhage

Call: PRELUDIUM 20 , Panel: NZ2

Principal investigator: Tomasz Klepinowski

Pomorski Uniwersytet Medyczny w Szczecinie

Screening for the molecular background of various coat depigmentation patterns in selected horse breeds kept in Poland

Call: PRELUDIUM 20 , Panel: NZ9

Principal investigator: Weronika Skrzetuska

Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

COLONISERS - COLONIsation of abySsal EnviRonmentS – phylogeny and zoogeography of deep-sea Typhlotanaidae (Tanaidacea: C...

Call: PRELUDIUM 20 , Panel: NZ8

Principal investigator: dr Marta Karolina Gellert

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Predicting 3D RNA structures using Generative Adversarial Networks

Call: PRELUDIUM BIS 2 , Panel: ST6

Principal investigator: prof. Marta Xymena Szachniuk

Politechnika Poznańska, Wydział Informatyki i Telekomunikacji

High throughput microfluidic system for fast determination of the equilibrium constant for biomolecular complexes: appli...

Call: PRELUDIUM BIS 2 , Panel: ST4

Principal investigator: prof. Robert Hołyst

Instytut Chemii Fizycznej Polskiej Akademii Nauk

LCRPlatform: new algorithms and methods for the comprehensive identification, categorization, and annotation of protein ...

Call: OPUS 20 , Panel: ST6

Principal investigator: dr hab. Marcin Maciej Grynberg

Instytut Biochemii i Biofizyki PAN

Plasma-based liquid biopsy for minimally invasive heart transplant monitoring

Call: OPUS 20 , Panel: NZ6

Principal investigator: dr hab. Piotr Wacław Siondalski

Gdański Uniwersytet Medyczny, Wydział Lekarski

Early migrations of the Goths in the light of specialized analyses

Call: OPUS 20 , Panel: HS3

Principal investigator: dr Maciej Chyleński

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii