Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Exploring the allosteric regulation of the SARS CoV-2 hydrolases using methyl-TROSY NMR spectroscopy - in search of novel binding sites for inhibitors.

2020/37/B/ST4/04017

Keywords:

COVID-19 NSP15 endoribonuclease 3CLpro protease allostery inhibitors large proteins advanced methods of NMR spectroscopy methyl-TROSY isotopic labelling strategies

Descriptors:

  • ST4_2: Spectroscopic and spectrometric techniques
  • ST4_9: Biological chemistry
  • NZ1_3: Biophysics

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Warszawski, Wydział Chemii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Wiktor Koźmiński 

Number of co-investigators in the project: 7

Call: OPUS 19 - announced on 2020-03-16

Amount awarded: 2 529 600 PLN

Project start date (Y-m-d): 2021-01-19

Project end date (Y-m-d): 2025-01-18

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.