Projects funded by the NCN
Studies of the permeation of anthocyanins and their metabolites through the brain barriers in the context of the preventive strategies of neurodegenerative diseases
2015/17/B/NZ9/01733
Keywords:
brain barriers cerebrospinal fluid anthocyanins cyanidin metabolites protocatechuic acid chokeberry red cabbage prevention central nervous system diseases
Descriptors:
- NZ9_7: Nutrition and food sciences
- NZ9_13: Other related subjects
Panel:
NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation
Host institution :
Instytut Rozrodu Zwierząt i Badań Żywności PAN
woj. warmińsko-mazurskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 11
Call: OPUS 9 - announced on 2015-03-16
Amount awarded: 699 900 PLN
Project start date (Y-m-d): 2016-02-15
Project end date (Y-m-d): 2020-02-14
Project duration:: 48 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (3)
- The Blood−Cerebrospinal Fluid Barrier Is Selective for Red Cabbage Anthocyanins and Their MetabolitesAuthors:Natalia Płatosz, Natalia Bączek, Joanna Topolska, Dorota Szawara-Nowak, Tomasz Misztal, Wiesław WiczkowskiAcademic press:Journal of Agricultural and Food Chemistry (rok: 2020, tom: 68, strony: 8274-8285), Wydawca: ACS PublicationsStatus:PublishedDOI:10.1021/acs.jafc.0c03170 - link to the publication
- The blood-cerebrospinal fluid barrier features different permeability to cyanidin-3-galactoside and cyanidin-3-diglucoside-5-glucoside and their metabolites circulating in bloodAuthors:Natalia Płatosz, Natalia Bączek, Joanna Topolska, Dorota Szawara-Nowak, Wiesław WiczkowskiAcademic press:Journal of Agricultural and Food Chemistry (rok: 2022, ), Wydawca: ACS PublicationsStatus:Accepted for publicationDOI:10.1021/acs.jafc.2c03778 - link to the publication
- Chokeberry anthocyanins and their metabolites ability to cross the blood-cerebrospinal fluid barrierAuthors:Natalia PŁATOSZ, Natalia BĄCZEK, Joanna TOPOLSKA, Dorota SZAWARA-NOWAK, Janina SKIPOR, Stanisław MILEWSKI, Wiesław WICZKOWSKIAcademic press:Food Chemistry (rok: 2021, tom: 346, strony: nr art. 128730, 1-11), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.foodchem.2020.128730 - link to the publication