Projects funded by the NCN

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69 projects found matching your search criteria :

  1. The study of the role of mGluR8 in cancer cells - a potential target for new antitumor strategies

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr Danuta Jantas

    Instytut Farmakologii PAN

  2. Effect of paroxetine and risperidone on the heterodimerization of dopamine D2 and serotonin 5-HT1A receptor in the conte...

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: dr Magdalena Kolasa

    Instytut Farmakologii PAN

  3. Molecular markers of stress resilience in animal model of depression

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: prof. Marta Dziedzicka-Wasylewska

    Instytut Farmakologii PAN

  4. Research of mechanisms of antidepressant action of group II and III mGlu receptor ligands and their role in inducing rap...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

    Instytut Farmakologii PAN

  5. Functional dissection of three alpha(1)-adrenergic receptor subtypes in the effects of antidepressant drugs: exploitatio...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Irena Nalepa

    Instytut Farmakologii PAN

  6. Substructural Connectivity Fingerprint and Extreme Entropy Machines: A New Method of Compound Representation and Analysi...

    Call: PRELUDIUM 9 , Panel: ST6

    Principal investigator: Krzysztof Rataj

    Instytut Farmakologii PAN

  7. Unusual 5-HT6 receptor ligands

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: prof. Andrzej Bojarski

    Instytut Farmakologii PAN

  8. Halogen bonding - the role and significance in interactions of ligands with class A GPCRs

    Call: SONATA 8 , Panel: NZ7

    Principal investigator: dr Rafał Kurczab

    Instytut Farmakologii PAN

  9. Znaczenie interakcji układu endokanabinoidowego i endowaniloidowego w leczeniu bólu przewlekłego - potencjał terapeutycz...

    Call: ETIUDA 3 , Panel: NZ7

    Principal investigator: Natalia Małek

    Instytut Farmakologii PAN

  10. Identification of cytochrome P450 isoenzymes involved in the metabolism of levomepromazine in the human

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: dr hab. Jacek Wójcikowski

    Instytut Farmakologii PAN

  11. Neuroplasticity regulation by alternative gene transcription

    Call: SONATA 2 , Panel: NZ3

    Principal investigator: dr Michał Korostyński

    Instytut Farmakologii PAN

  12. Glucocorticoid-induced alterations of astrocytic metabolism in stress-related disorders.

    Call: OPUS 2 , Panel: NZ3

    Principal investigator: dr Michał Ślęzak

    Instytut Farmakologii PAN

  13. Neurobiological basis of sensation seeking behaviour

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: Magdalena Sikora

    Instytut Farmakologii PAN

  14. Activation of endogenous pronociceptive mechanisms of opioid system as an important factors in the development of neurop...

    Call: MAESTRO 3 , Panel: NZ4

    Principal investigator: prof. Barbara Przewłocka

    Instytut Farmakologii PAN

  15. The group III metabotropic glutamate receptors as a target for future antypsychotic drugs

    Call: MAESTRO 3 , Panel: NZ7

    Principal investigator: prof. Andrzej Pilc

    Instytut Farmakologii PAN

  16. Effects of restraint stress on properties of neurons and synaptic transmission in hypothalamic paraventricular nucleus o...

    Call: PRELUDIUM 4 , Panel: NZ4

    Principal investigator: Magdalena Kusek

    Instytut Farmakologii PAN

  17. The effect of enriched environment on the epigenetic mechanism in neurodevelopmental model of schizophrenia.

    Call: PRELUDIUM 4 , Panel: NZ4

    Principal investigator: dr Ewelina Bator

    Instytut Farmakologii PAN

  18. The role of chemokines in the pathogenesis of depression and molecular mechanism of action of antidepressants.

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii PAN

  19. Neuronal and nonneuronal mechanisms of Bont/A effects in neuropathic pain development - behavioral and biochemical studi...

    Call: HARMONIA 5 , Panel: NZ4

    Principal investigator: dr hab. Joanna Mika

    Instytut Farmakologii PAN

  20. Pessimism as cognitive biomarker of depression in animal model

    Call: OPUS 7 , Panel: NZ4

    Principal investigator: dr hab. Rafał Ryguła

    Instytut Farmakologii PAN

  21. The role of the factors involved in the brain glucose metabolism in the model of obesity and depression comorbidity

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: prof. Bogusława Budziszewska

    Instytut Farmakologii PAN

  22. Examine the importance of intracellular pathways in the action of opioids in microglial cells in vitro

    Call: PRELUDIUM 4 , Panel: NZ3

    Principal investigator: Katarzyna Popiołek-Barczyk

    Instytut Farmakologii PAN

  23. The research of molecular markers for neuroprotective effect of tetrahydroisoquinolines based on various eksperimental m...

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: dr Agnieszka Wąsik

    Instytut Farmakologii PAN

  24. The effects of positive allosteric modulators of alpha7 nicotinic acetylcholine receptors on complex cognitive processes...

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Nikiforuk

    Instytut Farmakologii PAN

  25. The influence of glucagon-like peptied-1 receptor agaonists on regulation of coticotropin-releasing hormone gene promote...

    Call: PRELUDIUM 4 , Panel: NZ7

    Principal investigator: Jan Detka

    Instytut Farmakologii PAN

  26. Research on influence of antidepressant drugs on serum and brain levels of neurotrophins in rats, affected by the time d...

    Call: OPUS 4 , Panel: NZ4

    Principal investigator: dr Maciej Kuśmider

    Instytut Farmakologii PAN

  27. Transcription factor MeCP2 as an intracellular object of study on the mechanism of depression and as a potential pharmac...

    Call: SONATA 5 , Panel: NZ7

    Principal investigator: dr Magdalena Sowa-Kućma

    Instytut Farmakologii PAN

  28. Development of a tool for automatic evaluation of complexes of ligands with serotonin receptors based on the application...

    Call: PRELUDIUM 5 , Panel: NZ2

    Principal investigator: Sabina Podlewska

    Instytut Farmakologii PAN

  29. "Legal Higsh"- CNS effects and neurotoxicity

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: prof. Krystyna Gołembiowska

    Instytut Farmakologii PAN

  30. Involvement of cyclooxygenase 2 in antidepressant-like effects of metabotropic glutamatergic receptors group I.

    Call: SONATA 7 , Panel: NZ7

    Principal investigator: dr Katarzyna Stachowicz

    Instytut Farmakologii PAN

  31. The impact of maternal diabetes on inflammasome NLRP3 activation in the offspring brain

    Call: PRELUDIUM 7 , Panel: NZ7

    Principal investigator: dr Katarzyna Głombik

    Instytut Farmakologii PAN

  32. Neurotoxic effects of benzophenone-3 : the role of estrogen receptors and retinoid X receptor alpha.

    Call: PRELUDIUM 7 , Panel: NZ4

    Principal investigator: Agnieszka Wnuk

    Instytut Farmakologii PAN

  33. The effects of ligands of the alpha7 nicotinic acetylcholine receptors on complex cognitive processes and social behavio...

    Call: PRELUDIUM 8 , Panel: NZ7

    Principal investigator: Agnieszka Potasiewicz

    Instytut Farmakologii PAN

  34. Neural substrates of decision making under risk and uncertainty: role of phasic activity of dopamine neurons

    Call: PRELUDIUM 8 , Panel: NZ4

    Principal investigator: Przemysław Cieślak

    Instytut Farmakologii PAN

  35. Wykorzystanie metod uczenia maszynowego w zadaniach komputerowo wspomaganego projektowania leków.

    Call: ETIUDA 3 , Panel: NZ2

    Principal investigator: Sabina Podlewska

    Instytut Farmakologii PAN

  36. Contribution of nitrergic transmission in the modulation of L-dopa activity in the rat 6-OHDA model of Parkinson's disea...

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: dr hab. Elżbieta Lorenc-Koci

    Instytut Farmakologii PAN

  37. Pharmacological evaluation of possible neuroprotective strategies in novel genetic mouse models of progressive neurodege...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr Grzegorz Kreiner

    Instytut Farmakologii PAN

  38. Opioid receptors in the basal ganglia of the brain as targets for alcohol abuse therapy.

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr Jan Rodriguez Parkitna

    Instytut Farmakologii PAN

  39. The molecular basis of stress-induced anxiety and affective disorders

    Call: OPUS 2 , Panel: NZ2

    Principal investigator: dr Michał Korostyński

    Instytut Farmakologii PAN

  40. Probing the selectivity of zinc allosteric modulation in various serotonin receptor subtypes

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: Grzegorz Satała

    Instytut Farmakologii PAN

  41. The influence of the serotonergic system on the regulation of liver CYP activity in hepatocellular carcinoma

    Call: SONATA 4 , Panel: NZ4

    Principal investigator: dr Marta Kot

    Instytut Farmakologii PAN

  42. PHARMACOTHERAPY OF OSTEOARTHRITIS: TRPV1 AND CB1 RECEPTORS AND THEIR ENDOGENOUS LIGANDS AS NEW TARGETS FOR PHARMACOLOGIC...

    Call: SONATA BIS 2 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Starowicz-Bubak

    Instytut Farmakologii PAN

  43. Neural mechanisms underlying pathology of motivation.

    Call: SONATA BIS 2 , Panel: NZ3

    Principal investigator: dr Jan Rodriguez-Parkitna

    Instytut Farmakologii PAN

  44. Involvement of 5-HT1A receptor signal pathway in the antidepressant effect of zinc

    Call: HARMONIA 4 , Panel: NZ7

    Principal investigator: dr Bernadeta Szewczyk

    Instytut Farmakologii PAN

  45. Molecular mechanism for the effects of stress hormones on development of drug addiction

    Call: MAESTRO 4 , Panel: NZ3

    Principal investigator: prof. Ryszard Przewłocki

    Instytut Farmakologii PAN

  46. Effect of caffeine on neurotoxicity of methamphetamine and 3,4-methylenedioxymethamphetamine in the mouse brain.

    Call: PRELUDIUM 6 , Panel: NZ7

    Principal investigator: Anna Górska

    Instytut Farmakologii PAN

  47. The significance of the serotonergic innervation of the brain hypothalamus in the regulation of cytochrome P450

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: prof. Władysława Daniel

    Instytut Farmakologii PAN

  48. The impact of early-life stress (maternal separation) and fluctuation in corticosterone levels during adolescence on pre...

    Call: PRELUDIUM 9 , Panel: NZ4

    Principal investigator: Iwona Majcher-Maślanka

    Instytut Farmakologii PAN

  49. Effects of prenatal stress on properities of neurons and synaptic transmission in dorsal raphe nucleus of the rat

    Call: PRELUDIUM 9 , Panel: NZ4

    Principal investigator: Joanna Sowa

    Instytut Farmakologii PAN

  50. A virtual screening protocol based on automatically generated structure-based pharmacophore models.

    Call: HARMONIA 7 , Panel: NZ2

    Principal investigator: Stefan Mordalski

    Instytut Farmakologii PAN

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