Projects funded by the NCN

Functional analysis of detected genetic variants of the PCSK9 gene of unknown significance by using in vitro models

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Monika Marta Targońska

Gdański Uniwersytet Medyczny

Identification of circulating biomarkers for monitoring anti-CD19 CAR-T cell treatment response in patients with aggress...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Monika Szelest

Uniwersytet Medyczny w Lublinie

Determination of the effect of volume regulated anion channels (VRACs) on the neurovascular unit under ischemic conditio...

Call: OPUS 27 , Panel: NZ5

Principal investigator: prof. Joanna Maria Pera

Uniwersytet Jagielloński

Functional studies of TPM2 gene mutation responsible for the hereditary form of clubfoot disease

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Akshaya Ramanujam

Uniwersytet Medyczny w Lublinie

Impact of sodium chloride supplementation for natriuresis, blood pressure and neurohormonal activity in Chronic Heart Fa...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Mateusz Guzik

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Carbamylation in vascular calcification: new look at the hypertension etiology

Call: OPUS 27 , Panel: NZ5

Principal investigator: prof. Piotr Mateusz Mydel

Uniwersytet Jagielloński

Interleukin-6 role in stabilization of atherosclerotic plaque

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Małgorzata Gałdyszyńska

Uniwersytet Medyczny w Łodzi

The use of photosensitizers to improve the efficiency of radiotherapy

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Justyna Anna Czapla

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Identification of novel microRNA biomarkers in liquid biopsy of patients with neuroendocrine tumors

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Paweł Mateusz Komarnicki

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Breaking Down Defenses: The Impact of Periodontopathogen Porphyromonas gingivalis on Blood-Brain Barrier Functionality

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Kamila Justyna Drzazga

Uniwersytet Jagielloński

In search of the causes of type 1 diabetes in children with coexisting neurodevelopmental and neurological disorders - g...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Hanna Maria Kuśmierczyk-Kozieł

Uniwersytet Medyczny w Łodzi

The role of miRNAs (miR30a, miR30b, miR30c) in RARγ expression in acute myeloid leukemia (AML)

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Rafał Skopek

Instytut Genetyki i Hodowli Zwierząt PAN

Clonal and epigenetic pathways in the development of pediatric acute lymphoblastic leukemia.

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Jadwiga Maria Filipek-Gorzała

Uniwersytet Jagielloński

From methylation to malformation: the role of DNA methylation in the pathogenesis of Klippel-Feil syndrome

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Anna Szoszkiewicz

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Precision double strike against non-small cell lung cancer. Insights into multidirectional therapies and the landscape o...

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Katarzyna Anna Malarz

Politechnika Śląska

Neutrophil-targeted immune response as an effective approach in immunotherapyof gastrointestinal cancers

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Damian Jacenik

Uniwersytet Łódzki

Heterogeneity of perivascular adipose tissue in the browning process: at the crossroads of single-cell Raman spectroscop...

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Krzysztof Czamara

Uniwersytet Jagielloński

Insufficiency of antioxidant mechanisms and dysregulation of circulating miRNA profiles as a cause of delayed cerebral i...

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Karol Marek Wiśniewski

Uniwersytet Medyczny w Łodzi

Evaluation of the relationship between doxorubicin resistance, epithelial-mesenchymal plasticity, and effects of selecte...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Dominika Kunachowicz

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Evaluation of the role of miRNA as a peripheral biomarker of drug resistance in epilepsy using biosensors for electroche...

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr hab. Janusz Szyndler

Warszawski Uniwersytet Medyczny

Proteomic predictors of metastasis in colorectal cancer – a validation study

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr hab. Anna Wojakowska

Instytut Chemii Bioorganicznej PAN

Spatial visual transcriptomics approach of male and female gonad - validation of the role of candidate infertility genes...

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr hab. Marta Anna Olszewska

Instytut Genetyki Człowieka PAN

Search for new biomarkers useful in the diagnosis of adrenal tumors based on the analysis of selected metabolomic profil...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Alicja Szatko

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

Identification and characterization of omics profiles in patients' serum during anti-CD19 CAR-T cell therapy

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Jaromir Bartosz Tomasik

Warszawski Uniwersytet Medyczny

Discovery of quantitative biomarkers and exploration of variables underlying brain injury in the newborn via digital, mo...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Thomas Mark Kuncewicz

Uniwersytet Jagielloński

Comprehensive structural and functional analysis of p53 mRNA to identify secondary and tertiary RNA structures important...

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Leszek Michał Błaszczyk

Instytut Chemii Bioorganicznej PAN

The Prognostic Utility of Circulating Tumor Cells (CTCs) Derived from the Portal Vein in Operable Colorectal Cancer Pati...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Claudia Dompé

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

The association between the repair of oxidative DNA lesions and Th17/Treg cell homeostasis in Patients with Rheumatoid A...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Gabriela Filipowicz

Instytut Reumatologii im. prof. dr hab. med. Eleonory Reicher

The gut virome - a new important microbiome component in autism spectrum disorder

Call: SONATINA 8 , Panel: NZ5

Principal investigator: dr Kinga Eryka Gawlińska

Uniwersytet Jagielloński

New insight into the mechanism of cytotoxic brain edema in acute liver failure: focus on the functionality of mitochondr...

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Mariusz Paweł Popek

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Molecular mechanisms underlying the polycystic ovary syndrome

Call: OPUS 26 , Panel: NZ5

Principal investigator: prof. Nafis Ahmed Rahman

Uniwersytet Medyczny w Białymstoku

Potential pharmacological strategies aimed at alleviating cognitive dysfunctions accompanying oncological therapy while ...

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr hab. Joanna Monika Wierońska

Instytut Farmakologii PAN

Cellular senescence as a new mechanism in development and progression of head and neck cancer

Call: OPUS 26 , Panel: NZ5

Principal investigator: prof. Michał Mateusz Masternak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Multifunctional composites with broad bone and periodontal regeneration potential - a comprehensive approach to obtain n...

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr hab. Anna Osyczka

Uniwersytet Jagielloński, Wydział Biologii

Flozins as potential inhibitors of aortic stenosis progression in patients with concomitant type 2 diabetes: impact on v...

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr hab. Joanna Natorska

Uniwersytet Jagielloński

Defining the transcriptional and epigenetic state of tumor cells with increased plasticity and the epithelial-endothelia...

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr hab. Agnieszka Kobielak

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

In search for DNA methylation aberrations associated with susceptibility to ovarian cancer

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr Malwina Magdalena Suszyńska

Instytut Chemii Bioorganicznej PAN

To be or not to be modified: the role of single m6A sites of long noncoding RNAs in breast cancer

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Elżbieta Wanowska

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

ROS-Scavenging Magnetic Nanozymes with Remote Activation for Alzheimer Disease

Call: M-ERA.NET 3 Call 2023 , Panel: NZ5

Principal investigator: dr hab. Anna Ludwika Haduch

Instytut Farmakologii PAN

The role of oxidative stress, inflammation, disorders of purine metabolism, urea cycle and angiogenesis at the molecular...

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Paulina Wigner-Jeziorska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

ncRNA as formation of heterotopic ossifications predictors

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr hab. Edyta Elżbieta Brzóska-Wójtowicz

Uniwersytet Warszawski, Wydział Biologii

Protease-induced neutrophilic networks in cancer development.

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Danuta Teresa Bryzek

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Mitochondria-related mechanisms of exosome biogenesis and secretion in podocytes under metabolic stress.

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr Irena Audzeyenka

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

The gut-fetal brain axis as a promising key to deciphering the developmental origins of autism spectrum disorders

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Kinga Eryka Gawlińska

Uniwersytet Jagielloński, Collegium Medicum

Modulation of protein interaction networks as a new therapeutic target in the treatment of hereditary retinal dystrophie...

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Xiaonan Liu

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

Application of artificial intelligence to predict the presence of left atrial appendage thrombus based on transthoracic ...

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Konrad Pieszko

Uniwersytet Zielonogórski, Collegium Medicum

Targeting mitochondrial potassium channels to regulate cellular senescence.

Call: OPUS 26 , Panel: NZ5

Principal investigator: prof. Adam Michał Szewczyk

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

The sinonasal microbiome - temporal dynamics and alterations caused by selective antibiotic pressure.

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Joanna Agnieszka Szaleniec

Uniwersytet Jagielloński, Collegium Medicum

Novel aspects of the mechanisms of vascular toxicity of tyrosine kinase inhibitors: studies on their proinflammatory act...

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr Tomasz Krzysztof Prajsnar

Uniwersytet Jagielloński, Wydział Biologii

Increasing sensitivity to immunotherapy in lung cancer via immunostimulation and modulation of tumor microenvironment

Call: SONATA BIS 13 , Panel: NZ5

Principal investigator: dr Urszula Oleksiewicz

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu