Search results

351. Directed screening and evaluation of novel bactericidal compounds active againsttubercle bacilli and Mycobacterium absce…

Principal investigator: prof. Jarosław Dziadek

Instytut Biologii Medycznej PAN

Call: OPUS 25, Panel: NZ7

352. Compounds modulating function of telomeric proteins TRF1 and TRF2

Principal investigator: prof. Maciej Wojciech Bagiński

Politechnika Gdańska, Wydział Chemiczny

Call: OPUS 25, Panel: NZ7

353. Unraveling protease activation in stimulated CAR-T cells to identify new biomarkers for assessing their clinical efficac…

Principal investigator: dr hab. Małgorzata Firczuk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 25, Panel: NZ7

354. Inactivation of intracellular Staphylococcus aureus and staphylococcal enterotoxins with photoactivated compounds in mod…

Principal investigator: dr hab. Joanna Nakonieczna

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Call: OPUS 25, Panel: NZ7

355. Neuroprotective effect of SGLT2i: direct influence on amyloid-β related pathology

Principal investigator: Agnieszka Pawlos

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: PRELUDIUM 22, Panel: NZ7

356. Curdlan-based biomaterial as a nanostructure carrier for controlled and targeted drug delivery in the treatment of deep …

Principal investigator: dr Aleksandra Nurzyńska

Uniwersytet Medyczny w Lublinie

Call: PRELUDIUM 22, Panel: NZ7

357. Anticancer potential of TMPyP4 porphyrin in breast cancer photodynamic therapy and evaluation of the treatment safety

Principal investigator: prof. Błażej Rubiś

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: OPUS 25, Panel: NZ7

358. Do metal nanoparticles affect the biosynthesis of bioactive plant metabolites? - studies on an in vitro culture model of…

Principal investigator: dr hab. Agnieszka Szopa

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 25, Panel: NZ7

359. The cross-talk between 5-HTR2A and mGluR2 as a window for antidepressant effects of psilocybin.

Principal investigator: prof. Andrzej Mikołaj Pilc

Instytut Farmakologii PAN

Call: OPUS 25, Panel: NZ7

360. Understanding the contribution of immunoproteasome activation to the neuropathic pain development.

Principal investigator: dr Natalia Eleonora Małek-Chudzik

Politechnika Wrocławska

Call: OPUS 25, Panel: NZ7

361. Amorphous Senolytics: A Breakthrough Approach in Senescence Modulation and Age-Related Disease Treatment

Principal investigator: Szymon Sip

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Call: PRELUDIUM 22, Panel: NZ7

362. Targeting the serotonin 5-HT7 receptor in a search for new strategies of mental disorders treatment

Principal investigator: Patryk Pyka

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 22, Panel: NZ7

363. Search for novel IKK-β inhibitors in the context of diseases with neuroinflammatory origin – structure-based drug design…

Principal investigator: Emilia Aleksandra Sługocka

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 22, Panel: NZ7

364. Targeting Energy Metabolism for Precision Cancer Therapy: Novel Inhibitors of LDH-A and PDK1 as Potential Strategies to …

Principal investigator: Marika Anna Frańczak

Gdański Uniwersytet Medyczny, Wydział Lekarski

Call: PRELUDIUM 22, Panel: NZ7

365. "I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr…

Principal investigator: dr hab. Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: OPUS 25, Panel: NZ7

366. Chiral hybrids of quinones and quinols with double anticancer and antimicrobial activity against drug-resistant pathogen…

Principal investigator: prof. Ryszard Józef Ostaszewski

Instytut Chemii Organicznej Polska Akademia Nauk

Call: OPUS 25, Panel: NZ7

367. The Way to longevity - Effects of resveratrol or/and nanodiamonds on sirtuin activity in Acheta domesticus

Principal investigator: Patrycja Joanna Ziętara-Krzyk

UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

Call: PRELUDIUM 22, Panel: NZ7

368. Are bisphenol S and F safe substitutes for bisphenol A in the face of environmental contamination with estrogenic mycoto…

Principal investigator: Marta Justyna Kozieł

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: PRELUDIUM 22, Panel: NZ7

369. Assessment of twin screw extrusion potential as a continuous and scalable method of mechanochemical synthesis of active …

Principal investigator: Anna Magdalena Gołkowska

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Farmaceutyczny

Call: PRELUDIUM 22, Panel: NZ7

370. Designing Active Inhibitors of SARS-CoV-2 Methyltransferases

Principal investigator: Alex Jun Matsuda

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Call: PRELUDIUM 22, Panel: NZ7

371. The Role of the Mitochondrial Unfolded Protein Response (UPRmt) in Endothelial Function: a Possible Novel Target for the…

Principal investigator: Sylwester Tycjan Mosiołek

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Call: PRELUDIUM 22, Panel: NZ7

372. unESKAPEable. Innovative antibiotics leads based on bifunctionalsed metallacarboranes to combat ESKAPE pathogens.

Principal investigator: Jakub Cebula

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: PRELUDIUM 22, Panel: NZ7

373. Selective PPARγ modulation by amorfrutin B as a novel therapeutic approach to chemotherapy-induced damage to mammalian b…

Principal investigator: Bernadeta Angelika Pietrzak-Wawrzyńska

Instytut Farmakologii PAN

Call: PRELUDIUM 22, Panel: NZ7

374. Toxicity prediction for Novichoks: estimation of selected toxicological parameters for Novichoks as organophosphorus com…

Principal investigator: dr Maciej Noga

Instytut Ekspertyz Medycznych w Łodzi

Call: PRELUDIUM 22, Panel: NZ7

375. Unveiling the molecular signature underlying resistance to CD19 CAR-T therapy in malignant cells.

Principal investigator: Marta Krawczyk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM 22, Panel: NZ7

376. Modeling of the excipients effect on drug skin permeability

Principal investigator: Laura Agnieszka Krumpholz

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 22, Panel: NZ7

377. Chemosensors with molecularly imprinted polymers for determination of antiviral active drug substances in body fluids - …

Principal investigator: dr Krzysztof Robert Noworyta

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Call: OPUS 25, Panel: NZ7

378. Design, Synthesis and Characterization of Functionalized 1,2,4-Trioxanes/Trioxepanes for Antimalarial and Anticancer Use

Principal investigator: dr Mohit Kumar Tiwari

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: SONATINA 7, Panel: NZ7

379. Blood plasma microRNA profile as a basis for detecting Alzheimer's disease and dementia risk in pre-symptomatic individu…

Principal investigator: prof. Urszula Wojda

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 24, Panel: NZ7

380. The role of microvesicles in shaping exercise capacity in horses

Principal investigator: dr Olga Danuta Witkowska-Piłaszewicz

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Medycyny Weterynaryjnej

Call: SONATA 18, Panel: NZ7

381. CHIRAL RHENIUM AND RHODIUM COMPLEXES OF ANTICANCER AND ANTIBACTERIAL ACTIVITY: SYNTHESIS, ACTIVITY, AND PHYSICOCHEMICAL …

Principal investigator: prof. Jan Czesław Dobrowolski

Narodowy Instytut Leków

Call: OPUS 24, Panel: NZ7

382. Potential of TH cell profiling in personalized multiple sclerosis treatmentplanning.

Principal investigator: dr hab. Katarzyna Donskow-Łysoniewska

Uczelnia Łazarskiego

Call: OPUS 24, Panel: NZ7

383. Development of novel anti-cancer immunotherapy against mesothelioma comprising of oncolytic adenovirus vectors armed wit…

Principal investigator: dr Łukasz Kuryk

Narodowy Instytut Zdrowia Publicznego - Państwowy Zakład Higieny (NIZP - PZH)

Call: SONATA 18, Panel: NZ7

384. Effect of the chronic treatment with lamotrigine on changes in expression of genes related to seizure processes in the s…

Principal investigator: prof. Kinga Katarzyna Borowicz

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

Call: PRELUDIUM BIS 4, Panel: NZ7

385. Evaluation of anti-neoplastic activity of LAB-derived postbiotics as a potential tool to support standard chemotherapy i…

Principal investigator: prof. Janusz Zbigniew Szemraj

Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

Call: PRELUDIUM BIS 4, Panel: NZ7

386. Precise molecular characterization of circulating tumour cells in patients with triple negative breast cancer using high…

Principal investigator: prof. Stefano Volinia

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Call: OPUS 24, Panel: NZ7

387. Effects of tyrosine kinase inhibitors on Syk pathway in eNOS-based platelet subpopulations and on endothelial barrier in…

Principal investigator: dr hab. Aneta Iwona Radziwon-Balicka

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Call: POLONEZ BIS 3, Panel: NZ7

388. Neuroprotective properties of β-cyclodextrin-1,2,4-triazole inclusion complexes

Principal investigator: prof. Tomasz Sylwester Plech

Uniwersytet Medyczny w Lublinie

Call: PRELUDIUM BIS 4, Panel: NZ7

389. Targeted inhibition of hypusination pathway

Principal investigator: dr Przemysław Marek Grudnik

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Call: OPUS 24, Panel: NZ7

390. Targeted poloxamer micelles with selected drugs as a strategy for overcoming the mechanisms of multidrug resistance in p…

Principal investigator: prof. Tomasz Adam Gośliński

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: PRELUDIUM BIS 4, Panel: NZ7

391. Research on the preparation of new, hydrogel nanosystems for targeted therapy of colorectal cancer

Principal investigator: dr Urszula Helena Piotrowska

Warszawski Uniwersytet Medyczny

Call: SONATA 18, Panel: NZ7

392. Assessment of the risk of tolerance, resistance and co-selection under various stress conditions in Escherichia coli.

Principal investigator: dr Aleksandra Małgorzata Rapacka-Zdończyk

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Call: SONATA 18, Panel: NZ7

393. Customized DNA-based nanocarriers to boost heart healing

Principal investigator: dr Monika Bzowska

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: M-ERA.NET 2022, Panel: NZ7

394. Step beyond classical lipophilicity - modeling of phospholipids affinity using immobilized artificial membranes chromato…

Principal investigator: dr hab. Krzesimir Ciura

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Call: SONATA 18, Panel: NZ7

395. Extracellular vesicles as mediators of intercellular communication in an organism exposed to PET microplastics - multi-o…

Principal investigator: Karol Mierzejewski

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

Call: OPUS 24, Panel: NZ7

396. Exploring the unknown drug-like chemical space: new classes of sulfoximine derivatives and their biological activities.

Principal investigator: prof. Maciej Filip Dawidowski

Warszawski Uniwersytet Medyczny

Call: OPUS 24, Panel: NZ7

397. Identification of key structural elements of immunomodulatory proteins - inhibitors of antigenic peptide transporter TAP…

Principal investigator: dr Natalia Anna Karska

Uniwersytet Gdański, Wydział Chemii

Call: SONATA 18, Panel: NZ7

398. Gaining control on XBP1s signaling as a starting point for novel cancer therapies

Principal investigator: prof. Rafał Artur Bartoszewski

Uniwersytet Wrocławski, Wydział Biotechnologii

Call: OPUS 24, Panel: NZ7

399. High-throughput PET imaging by decoding multi-photon signals on long axial field-of-view PET using physics-guided artifi…

Principal investigator: prof. Ewa Łucja Stępień

Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Call: OPUS 24 (LAP), Panel: NZ7

400. A double whammy for the NF-κB signalling pathway: development of TAK1 and IKKβ degraders against inflammation-driven dis…

Principal investigator: dr hab. Anna Karolina Więckowska

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 24 (LAP), Panel: NZ7

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