Projects funded by the NCN
The significance of Zc3h12a gene deletion in hepatocytes and proximal tubular epithelial cells for neoplastic transformation and sorafenib resistance
2022/47/B/NZ5/02724
Keywords:
MCPIP1 neoplastic transformation liver kidney resistance
Descriptors:
- NZ3_001:
- NZ4_004:
- NZ5_007:
Panel:
NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution :
Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 6
Call: OPUS 24 - announced on 2022-07-15
Amount awarded: 2 333 632 PLN
Project start date (Y-m-d): 2023-07-06
Project end date (Y-m-d): 2027-07-05
Project duration:: 48 months (the same as in the proposal)
Project status: Pending project
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Articles in post-conference publications (2)
- Lack of MCPIP1 enzymatic activity leads to neoplastic transformation of normal kidney cellsAuthors:Paulina Marona; Iga Piasecka; Judyta Gorka; Oliwia Kwapisz; Rafal Myrczek; Ewelina Pospiech; Jolanta Jura; Katarzyna MiekusConference:Cancer Research (rok: 2024, tom: AACR Annual Meeting 2024, strony: 3017), Wydawca: AMER ASSOC CANCER RESEARCHData:konferencja 05.04.2024-10.04.2024Status:PublishedDOI:10.1158/1538-7445.AM2024-3017 - link to the publication
- The MCPIP1 protein – a key protector against neoplastic transformationAuthors:Paulina Marona, Oliwia Kwapisz, Iga Piasecka, Judyta Górka, Jolanta Jura, Katarzyna MiękusConference:FEBS OpenBio (rok: 2024, tom: The 48th FEBS Congress, strony: 319-320), Wydawca: FEBS PressData:konferencja 29.06.2024-03.07.2024Status:PublishedDOI:10.1002/2211-5463.13837 - link to the publication