Breast cancer metastasis-induced endothelial-mesenchymal transition alongside ageing; implications for therapy

2021/41/B/NZ5/02374

Keywords

Descriptors

  • NZ5_002: Etiologia chorób zwierząt
  • NZ5_004: Patogeneza chorób zwierząt
  • NZ5_008: Leczenie chorób zwierząt

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Marta Maria Smęda

Number of co-investigators in the project: 8

Call

OPUS 21 – announced on 2021-03-15

Amount awarded
3 045 370 PLN
Project start date
2022-01-25
Project end date
2026-09-24
Project duration
56 months (the same as in the proposal)
Project status
Pending project

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (2)

  1. A possible role of plasmin-dependent activation of TGF-β in cancer-associated thrombosis: Implications for therapy

    Authors:
    Marta Smeda, Ebrahim H Maleki, Agnieszka Jasztal
    Academic press:
    Cancer and Metastasis Reviews (year: 2024, volume: 44, pages: 2), Publisher: Springer Nature
    Status:
    Published
    DOI:
    10.1007/s10555-024-10222-6 – link to the publication
  2. Endothelial-mesenchymal transition induced by metastatic 4T1 breast cancer cells in pulmonary endothelium in aged mice

    Authors:
    Marta Smeda, Agnieszka Jasztal, Ebrahim H Maleki, Anna Bar, Magdalena Sternak, Grzegorz Kwiatkowski, Joanna Suraj-Prażmowska, Bartosz Proniewski, Anna Kieronska-Rudek, Kamila Wojnar-Lason, Klaudia Skrzypek, Marcin Majka, Karolina Chrabaszcz, Kamilla Malek, Stefan Chlopicki
    Academic press:
    Frontiers in Molecular Biosciences (year: 2022, volume: 9, pages: 1050112), Publisher: Frontiers
    Status:
    Published
    DOI:
    10.3389/fmolb.2022.1050112 – link to the publication

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