Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Breast cancer metastasis-induced endothelial-mesenchymal transition alongside ageing; implications for therapy

2021/41/B/NZ5/02374

Keywords:

endothelial-mesenchymal transition metastasis breast cancer aging platelets

Descriptors:

  • NZ5_002:
  • NZ5_004:
  • NZ5_008:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Marta Maria Smęda 

Number of co-investigators in the project: 8

Call: OPUS 21 - announced on 2021-03-15

Amount awarded: 3 045 370 PLN

Project start date (Y-m-d): 2022-01-25

Project end date (Y-m-d): 2026-09-24

Project duration:: 56 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Endothelial-mesenchymal transition induced by metastatic 4T1 breast cancer cells in pulmonary endothelium in aged mice
    Authors:
    Marta Smeda, Agnieszka Jasztal, Ebrahim H Maleki, Anna Bar, Magdalena Sternak, Grzegorz Kwiatkowski, Joanna Suraj-Prażmowska, Bartosz Proniewski, Anna Kieronska-Rudek, Kamila Wojnar-Lason, Klaudia Skrzypek, Marcin Majka, Karolina Chrabaszcz, Kamilla Malek, Stefan Chlopicki
    Academic press:
    Frontiers in Molecular Biosciences (rok: 2022, tom: 9, strony: 1050112), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fmolb.2022.1050112 - link to the publication
  2. Endothelial-mesenchymal transition induced by metastatic 4T1 breast cancer cells in pulmonary endothelium in aged mice
    Authors:
    Marta Smeda, Agnieszka Jasztal, Ebrahim H Maleki, Anna Bar, Magdalena Sternak, Grzegorz Kwiatkowski, Joanna Suraj-Prażmowska, Bartosz Proniewski, Anna Kieronska-Rudek, Kamila Wojnar-Lason, Klaudia Skrzypek, Marcin Majka, Karolina Chrabaszcz, Kamilla Malek, Stefan Chlopicki
    Academic press:
    Frontiers in Molecular Biosciences (rok: 2022, tom: 9, strony: 1050112), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fmolb.2022.1050112 - link to the publication
  3. A possible role of plasmin-dependent activation of TGF-β in cancer-associated thrombosis: Implications for therapy
    Authors:
    Marta Smeda, Ebrahim H Maleki, Agnieszka Jasztal
    Academic press:
    Cancer and Metastasis Reviews (rok: 2024, tom: 44, strony: 2), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1007/s10555-024-10222-6 - link to the publication
  4. A possible role of plasmin-dependent activation of TGF-β in cancer-associated thrombosis: Implications for therapy
    Authors:
    Marta Smeda, Ebrahim H Maleki, Agnieszka Jasztal
    Academic press:
    Cancer and Metastasis Reviews (rok: 2024, tom: 44, strony: 2), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1007/s10555-024-10222-6 - link to the publication

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