Projects funded by the NCN
Mechanisms controlling endocytosis of CD14 as targets for regulation of inflammatory responses of macrophages
2020/39/B/NZ3/02517
Keywords:
CD14 GPI-anchored protein plasma membrane ceramide inflammasome inflammation inflammatory response lipopolysaccharide macrophages nanodomains oxPAPC presepsin sepsis S-palmitoylation sphingomyelin sphingomyelin synthase 2 sphingosine TLR4
Descriptors:
- NZ3_002:
- NZ3_007:
- NZ6_001:
Panel:
NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution :
Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: OPUS 20 - announced on 2020-09-15
Amount awarded: 1 885 480 PLN
Project start date (Y-m-d): 2021-06-30
Project end date (Y-m-d): 2026-04-29
Project duration:: 58 months (the same as in the proposal)
Project status: Pending project
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- Białko CD14 jako modulator odpowiedzi zapalnejAuthors:Anna Ciesielska, Ichrak Ben Amor, Katarzyna KwiatkowskaAcademic press:Postępy Biochemii (rok: 2023, tom: 69, strony: 274-282), Wydawca: Polskie Towarzystwo BiochemiczneStatus:PublishedDOI:10.18388/pb.2021_501 - link to the publication
- Flotillins affect LPS-induced TLR4 signaling by modulating the trafficking and abundance of CD14Authors:Orest V Matveichuk, Anna Ciesielska, Aneta Hromada-Judycka, Natalia Nowak, Ichrak Ben Amor, Gabriela Traczyk, Katarzyna KwiatkowskaAcademic press:Cellular and Molecular Life Sciences (rok: 2024, tom: 191, strony: 45682), Wydawca: Springer NatureStatus:PublishedDOI:10.1007/s00018-024-05221-3 - link to the publication