Projects funded by the NCN
The effect of STING stimulation on neutrophils polarisation in the tumor microenvironment.
2019/35/N/NZ5/02506
Keywords:
neutrophils STING protein tumor microenvironment
Descriptors:
- NZ5_007:
- NZ6_001:
Panel:
NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution :
Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 3
Call: PRELUDIUM 18 - announced on 2019-09-16
Amount awarded: 210 000 PLN
Project start date (Y-m-d): 2020-07-20
Project end date (Y-m-d): 2025-01-19
Project duration:: 54 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- Differential Response to Local Stimulator of Interferon Genes Agonist Administration in Tumors with Various Stimulator of Interferon Genes StatusesAuthors:Alina Drzyzga, Justyna Czapla, Sybilla Matuszczak, Barbara Łasut-Szyszka, Tomasz Cichoń, Ewelina Pilny, Magdalena Jarosz-Biej, Ryszard SmolarczykAcademic press:Cancers (rok: 2025, tom: 17(2), strony: 175), Wydawca: MDPIStatus:PublishedDOI:10.3390/cancers17020175 - link to the publication
- Targeting STING signalling polarizes tumor-associated neutrophils to boost anticancer and abscopal antimetastatic functionsAuthors:Alina Drzyzga, Justyna Czapla, Tomasz Cichoń, Sybilla Matuszczak, Ewelina Pilny, Magdalena Jarosz-Biej, Joanna Ciepła, Ryszard SmolarczykAcademic press:ImmunoTargets and Therapy (rok: 2026, tom: 15, strony: 46040), Wydawca: Dove Medical PressStatus:PublishedDOI:10.2147/ITT.S576457 - link to the publication