Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Elucidating the role of erythroid progenitor cells (EPCs) in the development of antibacterial immune response in the course of neoplastic disease

2019/35/B/NZ6/00540

Keywords:

tumor erythroid progenitor cells immune response arginase bacterial infection

Descriptors:

  • NZ5_007:
  • NZ6_001:
  • NZ5_003:

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Warszawski Uniwersytet Medyczny, Wydział Lekarski

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Dominika Anna Nowis 

Number of co-investigators in the project: 4

Call: OPUS 18 - announced on 2019-09-16

Amount awarded: 1 258 080 PLN

Project start date (Y-m-d): 2020-06-25

Project end date (Y-m-d): 2022-12-24

Project duration:: 30 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (7)
  1. Tumor Immune Evasion Induced by Dysregulation of Erythroid Progenitor Cells Development
    Authors:
    Grzywa TM, Justyniarska M, Nowis D, Golab J
    Academic press:
    Cancers (rok: 2021, tom: 13(4), strony: 870), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers13040870 - link to the publication
  2. The role of CD71+ erythroid cells in the regulation of the immune response
    Authors:
    Grzywa TM, Nowis D, Golab J.
    Academic press:
    Pharmacology and Therapeutics (rok: 2021, tom: 228, strony: 107927), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.pharmthera.2021.107927 - link to the publication
  3. Tumor Immune Evasion Induced by Dysregulation of Erythroid Progenitor Cells Development
    Authors:
    Grzywa TM, Justyniarska M, Nowis D, Golab J
    Academic press:
    Cancers (rok: 2021, tom: 13(4), strony: 870), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers13040870 - link to the publication
  4. The role of CD71+ erythroid cells in the regulation of the immune response
    Authors:
    Grzywa TM, Nowis D, Golab J.
    Academic press:
    Pharmacology and Therapeutics (rok: 2021, tom: 228, strony: 107927), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.pharmthera.2021.107927 - link to the publication
  5. CD71+ erythroid cells promote multiple myeloma progression and impair anti-bacterial immune response
    Authors:
    Czubak K, Grzywa TM, Sidor-Dzitkowska K, Pilch Z, Bielak K, Hoser G, Gewartowska O, Malecka-Gieldowska M, Barankiewicz J, Garbicz F, Ciepiela O, Juszczynski P, Owczarek A, Wegrzynowicz M, Skirecki T, Golab J, Nowis D.
    Academic press:
    British Journal of Haematology (rok: 2024, tom: Online ahead of print, strony: 45663), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/bjh.19914 - link to the publication
  6. Ablation of Tmcc2 Gene Impairs Erythropoiesis in Mice
    Authors:
    Kumari R, Grzywa TM, Małecka-Giełdowska M, Tyszkowska K, Wrzesień R, Ciepiela O, Nowis D, Kaźmierczak P.
    Academic press:
    Int J Mol Sci. (rok: 2022, tom: 23(9), strony: 45667), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23095263 - link to the publication
  7. Potent but transient immunosuppression of T-cells is a general feature of CD71+ erythroid cells
    Authors:
    Grzywa TM, Sosnowska A, Rydzynska Z, Lazniewski M, Plewczynski D, Klicka K, Malecka-Gieldowska M, Rodziewicz-Lurzynska A, Ciepiela O, Justyniarska M, Pomper P, Grzybowski MM, Blaszczyk R, Wegrzynowicz M, Tomaszewska A, Basak G, Golab J, Nowis D.
    Academic press:
    Communications Biology (rok: 2021, tom: 4, strony: 1384), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s42003-021-02914-4 - link to the publication

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