Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Encapsidic production of difficult-to-express proteins

2019/35/B/NZ1/02044

Keywords:

Recombinant protein/Protein cage/Directed evolution/Protein folding/Biotechnology

Descriptors:

  • NZ1_002:
  • NZ1_006:
  • NZ1_009:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Yusuke Azuma 

Number of co-investigators in the project: 7

Call: OPUS 18 - announced on 2019-09-16

Amount awarded: 2 280 960 PLN

Project start date (Y-m-d): 2020-10-01

Project end date (Y-m-d): 2025-09-30

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  • Book publications / chapters in book publications (1)
  1. Dynamic Assembly of Pentamer-Based Protein Nanotubes
    Authors:
    Lukasz Koziej, Farzad Fatehi, Marta Aleksejczuk, Matthew J. Byrne, Jonathan G. Heddle, Reidun Twarock, and Yusuke Azuma
    Academic press:
    ACS Nano (rok: 2025, tom: 19, strony: 8786–8798), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acsnano.4c16192 - link to the publication
  2. Encapsidic production and isolation of degradation-prone polypeptides
    Authors:
    Agnieszka Gawin, Jędrzej Pankowski, Maria Zarechyntsava, Dominika Kwasna, Damian Kloska, Lukasz Koziej, Sebastian Glatt, Neli Kachamakova-Trojanowska, and Yusuke Azuma
    Academic press:
    Journal of Materials Chemistry B (rok: 2025, tom: 13, strony: 12605-12613), Wydawca: The Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D5TB01033K - link to the publication
  1. Lumazine Synthase Protein Nanocompartments
    Authors:
    Lukasz Koziej, Agnieszka Gawin, and Yusuke Azuma
    Book:
    Microbiology Monographs, Microbial Production of High-Value Products (rok: 2022, tom: 37, strony: pp335-355), Wydawca: Springer-Nature Switzerland AG, Cham, Switzerland
    Status:
    Published
    DOI:
    10.1007/978-3-031-06600-9_13 - link to the publication