Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Galactosylceramide as a regulator of apoptotic gene expression and modulator of drug resistance in breast cancer cells.

2019/35/B/NZ5/01392

Keywords:

breast cancer galactosylceramide apoptosis drug resistance,

Descriptors:

  • NZ5_001:
  • NZ5_007:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Przyrodniczy we Wrocławiu, Wydział Medycyny Weterynaryjnej

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Maciej Ugorski 

Number of co-investigators in the project: 4

Call: OPUS 18 - announced on 2019-09-16

Amount awarded: 1 560 895 PLN

Project start date (Y-m-d): 2020-07-02

Project end date (Y-m-d): 2024-07-01

Project duration:: 48 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Galactosylceramide Upregulates the Expression of the BCL2 Gene and Downregulates the Expression of TNFRSF1B and TNFRSF9 Genes, Acting as an Anti-Apoptotic Molecule in Breast Cancer Cells
    Authors:
    Jarosław Suchański, Safoura Reza, Anna Urbaniak, Weronika Woldańska, Bartłomiej Kocbach, Maciej Ugorski
    Academic press:
    Cancers (rok: 2024, tom: 16, strony: 45676), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers16020389 - link to the publication
  2. Galactosylceramide Upregulates the Expression of the BCL2 Gene and Downregulates the Expression of TNFRSF1B and TNFRSF9 Genes, Acting as an Anti-Apoptotic Molecule in Breast Cancer Cells
    Authors:
    Jarosław Suchański, Safoura Reza, Anna Urbaniak, Weronika Woldańska, Bartłomiej Kocbach, Maciej Ugorski
    Academic press:
    Cancers (rok: 2024, tom: 16, strony: 45676), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers16020389 - link to the publication
  3. Glucosylceramide and galactosylceramide, small glycosphingolipids with significant impact on health and disease
    Authors:
    Safoura Reza, Maciej Ugorski, Jaroslaw Suchanski
    Academic press:
    Glycobiology (rok: 2021, tom: 31, strony: 1416-1436), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/glycob/cwab046 - link to the publication

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