The effect of high fat and high carbohydrate diet on molecular profile of inflammation in animal model of obesity in asthma
2019/35/B/NZ5/02906
Keywords
Descriptors
- NZ5_003: Patogeneza chorób człowieka
- NZ2_002: Genomika, transkryptomika i epigenomika
- NZ3_001: Biologia komórki
Panel
NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution
Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu
Voivodeship: wielkopolskie
Principal investigator (from the host institution)
prof. Aleksandra Maria Szczepankiewicz
Number of co-investigators in the project: 7
Call
OPUS 18 – announced on 2019-09-16
- Amount awarded
- 2 712 600 PLN
- Project start date
- 2020-07-22
- Project end date
- 2026-07-21
- Project duration
- 72 months (the same as in the proposal)
- Project status
- Pending project
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (7)
-
Small RNA-based formulations in precision cut lung slices - is there an alternative for in vivo/in vitro studies?
- Authors:
- Nowakowska-Lewicka J, Szczepankiewicz A.
- Academic press:
- Expert Rev Respir Med. (year: 2025, volume: -, pages: 46029), Publisher: Taylor and Francis Online
- Status:
- Published
- DOI:
- 10.1080/17476348.2025.2600109 – link to the publication
-
The Impact of Non-Coding RNA on Inflammation and Airway Remodeling in Asthma Related to Obesity: State-of-the-Art and Therapeutic Perspectives
- Authors:
- Maria Kachel, Wojciech Langwiński, Aleksandra Szczepankiewicz
- Academic press:
- J Clin Med. (year: 2025, volume: 14, pages: 7161), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/jcm14207161 – link to the publication
-
Effect of miR-223-3p and miR-328a-3p Knockdown on Allergic Airway Inflammation in Rat Precision-Cut Lung Slices
- Authors:
- Joanna Nowakowska, Maria Kachel, Wojciech Langwiński, Kamil Ziarniak, Aleksandra Szczepankiewicz
- Academic press:
- Cells (year: 2025, volume: 14(2), pages: 104), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/cells14020104 – link to the publication
-
Nitric Oxide Synthase 2 Promoter Polymorphism Is a Risk Factor for Allergic Asthma in Children
- Authors:
- Joanna Nowakowska, Paulina Sobkowiak, Anna Breborowicz, Magdalena Mrówczynska, Irena Wojsyk-Banaszak, Aleksandra Szczepankiewicz
- Academic press:
- Medicina (year: 2021, volume: 57, pages: 1341), Publisher: MDPI
- Status:
- Published
- DOI:
- link to the publication
-
Allergic Inflammation Alters microRNA Expression Profile in Adipose Tissue in the Rat.
- Authors:
- Szczepankiewicz D, Langwiński W, Kołodziejski P, Pruszyńska-Oszmałek E, Sassek M, Nowakowska J, Chmurzyńska A, Nowak KW, Szczepankiewicz A.
- Academic press:
- Genes (year: 2020, volume: 11(9), pages: 1034), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/genes11091034 – link to the publication
-
Increased expression of ORMDL3 in allergic asthma: a case control and in vitro study
- Authors:
- Nowakowska J, Olechnowicz A, Langwiński W, Koteluk O, Lemańska Ż, Jóźwiak K, Kamiński K, Łosiewski W, Stegmayr J, Wagner D, Alsafadi HN, Lindstedt S, Dziuba M, Bielicka A, Graczyk Z, Szczepankiewicz A.
- Academic press:
- J Asthma (year: 2022, volume: -, pages: 46032), Publisher: Taylor and Francis
- Status:
- Published
- DOI:
- 10.1080/02770903.2022.2056896 – link to the publication
-
Allergic inflammation in lungs and nasal epithelium of rat model is regulated by tissue-specific miRNA expression.
- Authors:
- Langwiński W, Szczepankiewicz D, Narożna B, Stegmayr J, Wagner D, Alsafadi H, Lindstedt S, Stachowiak Z, Nowakowska J, Skrzypski M, Szczepankiewicz A.
- Academic press:
- Mol Immunol (year: 2022, volume: 147, pages: 115-125), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.molimm.2022.04.017 – link to the publication