Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Ubiquitin as a modulator of the mitochondrial protein import process.

2019/34/E/NZ1/00321

Keywords:

ubiquitin ubiquitination protein proteostasis mitochondria protein transport

Descriptors:

  • NZ1_001:
  • NZ1_002:
  • NZ3_001:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Narodowy lnstytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy lnstytut Badawczy

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Piotr Mieczysław Brągoszewski 

Number of co-investigators in the project: 5

Call: SONATA BIS 9 - announced on 2019-06-17

Amount awarded: 3 394 800 PLN

Project start date (Y-m-d): 2020-04-14

Project end date (Y-m-d): 2026-04-13

Project duration:: 72 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  • Book publications / chapters in book publications (1)
  1. OMA1 protease eliminates arrested protein import intermediates upon mitochondrial depolarization
    Authors:
    5. Krakowczyk M, Lenkiewicz AM, Sitarz T, Malinska D, Borrero M, Mussulini BHM, Linke V, Szczepankiewicz AA, Biazik JM, Wydrych A, Nieznanska H, Serwa RA, Chacinska A, P. Bragoszewski
    Academic press:
    Journal of Cell Biology (JCB) (rok: 2024, tom: 223 (5), strony: e202306051), Wydawca: Rockefeller University Press
    Status:
    Published
    DOI:
    10.1083/jcb.202306051 - link to the publication
  2. Mechanisms of stress management in mitochondrial protein import
    Authors:
    Maryam Mukhtar; Krutika Thakkur; Agnieszka Chacinska; Piotr Bragoszewski
    Academic press:
    Biochemical Society Transactions (rok: 2023, tom: 51 (6), strony: 2117–2126), Wydawca: Portland Press / Biochemical Society
    Status:
    Published
    DOI:
    10.1042/BST20230377 - link to the publication
  3. Cytosolic Quality Control of Mitochondrial Protein Precursors - The Early Stages of the Organelle Biogenesis
    Authors:
    Anna M. Lenkiewicz, Magda Krakowczyk, Piotr Brągoszewski
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 23(1), 7., strony: 45684), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23010007 - link to the publication
  1. Monitoring retro-translocation of proteins from the mitochondrial intermembrane space
    Authors:
    Krakowczyk Magda i Brągoszewski Piotr
    Book:
    Methods in Enzymology: Mitochondrial Translocases Part B (rok: 2024, tom: Volume 707, strony: 173-208), Wydawca: elsevier
    Status:
    Published
    DOI:
    10.1016/bs.mie.2024.07.047 - link to the publication

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