Projects funded by the NCN
In search for new genes involved in primary ciliary dyskinesia pathogenesis: functional screening of candidate genes using RNA interference
2018/29/N/NZ5/00810
Keywords:
primary ciliary dyskinesia motile cilia ciliated epithelium respiratory tract candidate genes gene silencing mutations ciliated flatworm model
Descriptors:
- NZ5_3:
- NZ2_12:
Panel:
NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution :
Instytut Genetyki Człowieka Polskiej Akademii Nauk
woj. wielkopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 15 - announced on 2018-03-15
Amount awarded: 209 998 PLN
Project start date (Y-m-d): 2019-01-10
Project end date (Y-m-d): 2024-01-09
Project duration:: 60 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- Schmidtea mediterranea as a Model Organism to Study the Molecular Background of Human Motile CiliopathiesAuthors:Alicja Rabiasz, Ewa ZiętkiewiczAcademic press:International Journal of Molecular Sciences (rok: 2023, tom: 24, strony: nie dotyczy), Wydawca: MDPIStatus:PublishedDOI:10.3390/ijms24054472 - link to the publication
- The lack of homozygotes with a large deletion encompassing SPAG1 and POLR2K in primary ciliary dyskinesia patients suggests the lethal effect of the loss of POLR2K proteinAuthors:Alicja Rabiasz, Monika Drobna-Śledzińska, Patrycja Kaźmierczak, Michał Witt, Ewa ZiętkiewiczStatus:Accepted for publication