Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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CRISPR tools for the study of embryonic development in zebrafish

2017/27/L/NZ2/03234

Keywords:

CRISPR zebrafish Csm complex knockdown

Descriptors:

  • NZ1_9:
  • NZ2_1:
  • NZ3_13:

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Matthias Bochtler 

Number of co-investigators in the project: 4

Call: DAINA 1 - announced on 2017-09-15

Amount awarded: 1 634 500 PLN

Project start date (Y-m-d): 2018-09-01

Project end date (Y-m-d): 2023-08-31

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Targeted RNA Knockdown by a Type III CRISPR-Cas Complex in Zebrafish
    Authors:
    Thomas Fricke, Dalia Smalakyte, Maciej Lapinski, Abhishek Pateria, Charles Weige, Michal Pastor, Agnieszka Kolano, Cecilia Winata, Virginijus Siksnys, Gintautas Tamulaitis, and Matthias Bochtler
    Academic press:
    The CRISPR Journal (rok: 2020, tom: 4, strony: 299-313), Wydawca: Mary Ann Liebert, Inc
    Status:
    Published
    DOI:
    10.1089/crispr.2020.0032 - link to the publication
  2. Arrhenius-law-governed homo- and heteroduplex dissociation
    Authors:
    Matthias Bochtler
    Academic press:
    Physical Review E (rok: 2020, tom: 101, strony: 32405), Wydawca: American Physical Society
    Status:
    Published
    DOI:
    10.1103/PhysRevE.101.032405 - link to the publication
  3. Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish
    Authors:
    Niescierowicz, K., Pryszcz, L., Navarrete, C., Tralle, E., Sulej, A., Abu Nahia, K., Kasprzyk, M.E., Misztal, K., Pateria, A., Pakula, A. et al.
    Academic press:
    Nature Communications (rok: 2022, tom: 13, strony: 45671), Wydawca: Springer Nature Limited
    Status:
    Published
    DOI:
    10.1038/s41467-022-33260-6 - link to the publication
  4. Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish
    Authors:
    Niescierowicz, K., Pryszcz, L., Navarrete, C., Tralle, E., Sulej, A., Abu Nahia, K., Kasprzyk, M.E., Misztal, K., Pateria, A., Pakula, A. et al.
    Academic press:
    Nature Communications (rok: 2022, tom: 13, strony: 45671), Wydawca: Springer Nature Limited
    Status:
    Published
    DOI:
    10.1038/s41467-022-33260-6 - link to the publication