Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Metagenomics and metabolomics-based microbiome profiles to identify distal gut disbiosis correlating with cancer therapy outcomes

2017/27/B/NZ5/01504

Keywords:

cancer micorbiome metabolome 16SrRNA-Seq mass spectrometry

Descriptors:

  • NZ2_4:
  • NZ5_7:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jerzy Zygmunt Ostrowski 

Number of co-investigators in the project: 9

Call: OPUS 14 - announced on 2017-09-15

Amount awarded: 2 626 760 PLN

Project start date (Y-m-d): 2018-09-27

Project end date (Y-m-d): 2023-09-26

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Increased diversity of a cervical microbiome associates with cervical cancer
    Authors:
    Zeber-Lubecka N, Kulecka M, Lindner B, Krynicki R, Paziewska A, Nowakowski A, Bidzinski M, Ostrowski J.
    Academic press:
    Frontiers in Oncology (rok: 2022, tom: 12, strony: 1005537), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fonc.2022.1005537 - link to the publication
  2. Dysbiosis of the Upper Gastrointestinal Tract in Head-and-Neck Cancer Survivors: A Pilot Study Using the Capsule Sponge Device
    Authors:
    Natalia Zeber-Lubecka, Maria Kulecka, Michalina Dabrowska, Anna Kluska, Magdalena Piątkowska, Maryla Helena Turkot, Nastazja Dagny Pilonis, Aisha Yusuf, Karol Nowicki-Osuch, Michal Mikula, Jerzy Ostrowski
    Academic press:
    Cancers (rok: 2024, tom: 16, strony: 3528), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers16203528 - link to the publication
  3. Gene Expression-Based Functional Differences between the Bladder Body and Trigonal Urothelium in Adolescent Female Patients with Micturition Dysfunction
    Authors:
    Zeber-Lubecka N, Kulecka M, Załęska-Oracka K, Dąbrowska M, Bałabas A, Hennig EE, Szymanek-Szwed M, Mikula M, Jurkiewicz B, Ostrowski J.
    Academic press:
    Biomedicines (rok: 2022, tom: 10, strony: 1435), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/biomedicines10061435 - link to the publication
  4. Microbial and Metabolic Gut Profiling across Seven Malignancies Identifies Fecal Faecalibacillus intestinalis and Formic Acid as Commonly Altered in Cancer Patients
    Authors:
    Maria Kulecka, Paweł Czarnowski, Aneta Bałabas, Maryla Turkot, Kamila Kruczkowska-Tarantowicz, Natalia Żeber-Lubecka, Michalina Dąbrowska, Ewa Paszkiewicz-Kozik, Jan Walewski , Iwona Ługowska, Hanna Koseła-Paterczyk, Piotr Rutkowski, Anna Kluska, Magdalena Piątkowska, Agnieszka Jagiełło-Gruszfeld, Michał Tenderenda, Cieszymierz Gawiński, Lucjan Wyrwicz, Magdalena Borucka, Maciej Krzakowski, Leszek Zając, Michał Kamiński, Michał Mikula, Jerzy Ostrowski
    Academic press:
    Int J Mol Sci (rok: 2024, tom: 25, strony: 8026), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms25158026 - link to the publication

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