Projects funded by the NCN
The role of estrogen precursor-dehydroepiandrosteron (DHEA) in the pathogenesis of cholangiopathy associated with Primary Biliary Cholangitis (PBC)
2017/25/B/NZ5/00819
Keywords:
Primary Biliary Cholangitis estrogens DHEA
Descriptors:
- NZ5_3: Pathogenesis of human diseases
Panel:
NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution :
Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Nauk o Zdrowiu
woj. zachodniopomorskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 3
Call: OPUS 13 - announced on 2017-03-15
Amount awarded: 674 800 PLN
Project start date (Y-m-d): 2018-01-09
Project end date (Y-m-d): 2022-01-08
Project duration:: 48 months (the same as in the proposal)
Project status: Project settled
Project description
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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- DHEA protects human cholangiocytes and hepatocytes against apoptosis and oxidative stressAuthors:Kilanczyk E., Ruminkiewicz D., Banales JM., Milkiewicz P., Milkiewicz MAcademic press:Cells (rok: 2022, tom: 11, strony: 1038), Wydawca: MDPIStatus:PublishedDOI:10.3390/cells11061038 - link to the publication
- DHEA and its metabolites decreased levels of IL-8, IL-13 and TNF- in cholangiocytes and hepatocytesAuthors:Małgorzata Blatkiewicz 1#, Katarzyna Sielatycka 2,3#, Katarzyna Piotrowska 4 and Ewa Kilańczyk 5*Academic press:International Journal of Molecular Science , Wydawca: MDPIStatus:SubmittedDOI:brak - link to the publication