Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

The role of interaction between P1 purine receptors and nitric oxide bioavailability on intrarenal blood circulation and renal excretion during development in diabetes, in animal model.

2017/25/B/NZ5/01292

Keywords:

diabetes kidney blood flow kidney medulla P1 receptors tissue NO renal excretion,

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ5_9: Other related subjects

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Leszek Dobrowolski 

Number of co-investigators in the project: 5

Call: OPUS 13 - announced on 2017-03-15

Amount awarded: 573 400 PLN

Project start date (Y-m-d): 2018-01-30

Project end date (Y-m-d): 2022-01-29

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. zestaw do kontroli i utrzymywania stabilnej temperatury ciała podczas eksperymentów (6 730 PLN)
  2. Miernik amperometryczny do pomiaru poziomu NO i wolnych rodników (55 000 PLN)
  3. fotometr płomieniowy (40 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Interplay of the adenosine system and NO in control of renal haemodynamics and excretion: Comparison of normoglycaemic and streptozotocin diabetic rats
    Authors:
    Marta Kuczeriszka, Joanna Dorota Sitek, Agnieszka Walkowska, Janusz Sadowski, Leszek Dobrowolski
    Academic press:
    Nitric Oxide (rok: 2020, tom: 104-105, strony: 20-28), Wydawca: Elsevier Inc.
    Status:
    Published
    DOI:
    10.1016/j.niox.2020.08.003 - link to the publication
  2. Nonselective and A2a-Selective Inhibition of Adenosine Receptors Modulates Renal Perfusion and Excretion Depending on the Duration of Streptozotocin-Induced Diabetes in Rats
    Authors:
    Joanna Dorota Sitek, Marta Kuczeriszka, Agnieszka Walkowska, Elżbieta Kompanowska-Jezierska, Leszek Dobrowolski
    Academic press:
    Pharmaceuticals (rok: 2023, tom: 16 (5), strony: 732), Wydawca: Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/ph16050732 - link to the publication
  3. Minor age difference substantially affects renal function in conscious and anaesthetised rats
    Authors:
    Joanna Dorota Sitek, Agnieszka Walkowska, Marta Kuczeriszka, Leszek Dobrowolski*
    Academic press:
    Animal Science Papers And Reports (rok: 2023, ), Wydawca: Institute Of Genetics And Animal Biotechnology Ot The Polish Academy Of Sciences, Jastrzębiec, Poland
    Status:
    Submitted
    DOI:
    brak - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy