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Evaluation of platelet-derived extracellular vesicles and selected platelets-derived microRNAs in relation to platelet reactivity and their changes over time in patients with acute ischemic stroke

2017/25/N/NZ5/00545

Keywords:

microRNA platelet reactivity stroke diagnosis

Descriptors:

  • NZ5_5: Diagnostics in human diseases
  • NZ7_12: Prevention of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Warszawski Uniwersytet Medyczny, Wydział Lekarski

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Ceren Eyileten Postula 

Number of co-investigators in the project: 3

Call: PRELUDIUM 13 - announced on 2017-03-15

Amount awarded: 149 520 PLN

Project start date (Y-m-d): 2018-01-24

Project end date (Y-m-d): 2021-01-23

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (7)
  • Articles in post-conference publications (2)
  1. MicroRNAs as Diagnostic and Prognostic Biomarkers in Ischemic Stroke-A Comprehensive Review and Bioinformatic Analysis
    Authors:
    1.Eyileten C, Wicik Z, De Rosa S, Mirowska-Guzel D, Soplinska A, Indolfi C, Jastrzebska-Kurkowska I, Czlonkowska A, Postula M
    Academic press:
    Cells (rok: 2018, tom: 7(12), strony: 12420), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells712024 - link to the publication
  2. The relation of the brain-derived neurotrophic factor with microRNAs in neurodegenerative diseases and ischemic stroke
    Authors:
    Eyileten, Ceren, Lucia Sharif, Zofia Wicik, Daniel Jakubik, Joanna Jarosz-Popek, Aleksandra Soplinska, Marek Postula, Anna Czlonkowska, Agnieszka Kaplon-Cieslicka, and Dagmara Mirowska-Guzel
    Academic press:
    Molecular neurobiology (rok: 2020, tom: 58, strony: 329-347), Wydawca: Springer Science+Business Media
    Status:
    Published
    DOI:
    10.1007/s12035-020-02101-2 - link to the publication
  3. The role of miRNAs in regulation of platelet activity and related diseases - a bioinformatic analysis
    Authors:
    Zofia Wicik, Pamela Czajka, Ceren Eyileten, Alex Fitas, Marta Wolska, Daniel Jakubik, Dirk von Lewinski, Harald Sourij, Jolanta M. Siller-Matula & Marek Postula
    Academic press:
    Platelets (rok: 2022, ), Wydawca: Taylor and Francis Online
    Status:
    Published
    DOI:
    10.1080/09537104.2022.2042233 - link to the publication
  4. Diagnostic Performance of Circulating miRNAs and Extracellular Vesicles in Acute Ischemic Stroke
    Authors:
    Ceren Eyileten, Daniel Jakubik, Andleeb Shahzadi, Aleksandra Gasecka, Edwin van der Pol, Salvatore De Rosa, Dominika Siwik, Magdalena Gajewska, Dagmara Mirowska-Guzel, Iwona Kurkowska-Jastrzebska, Anna Czlonkowska and Marek Postula
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 4530), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ - link to the publication
  5. Early Biomarkers of Neurodegenerative and Neurovascular Disorders in Diabetes
    Authors:
    Gasecka, Aleksandra, Dominika Siwik, Magdalena Gajewska, Miłosz J. Jaguszewski, Tomasz Mazurek, Krzysztof J. Filipiak, Marek Postuła, Ceren Eyileten
    Academic press:
    Journal of Clinical Medicine (rok: 2020, tom: 9(9), strony: 45313), Wydawca: Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/jcm9092807 - link to the publication
  6. Long Non-coding RNAs as Promising Therapeutic Approach in Ischemic Stroke: a Comprehensive Review
    Authors:
    Wolska M, Jarosz-Popek J, Junger E, Wicik Z, Porshoor T, Sharif L, Czajka P, Postula M, Mirowska-Guzel D, Czlonkowska A, Eyileten C.
    Academic press:
    Molecular Neurobiology (rok: 2020, tom: 58, strony: 1664-1882), Wydawca: Springer Science+Business Media
    Status:
    Published
    DOI:
    10.1007/s12035-020-02206-8 - link to the publication
  7. Plasma Concentrations of Extracellular Vesicles Are Decreased in Patients with Post-Infarct Cardiac Remodelling
    Authors:
    Aleksandra Gąsecka, Kinga Pluta,Katarzyna Solarska, Bartłomiej Rydz, Ceren Eyileten, Marek Postula, Edwin van der Pol, Rienk Nieuwland, Monika Budnik, Janusz Kochanowski, Miłosz J. Jaguszewski, Łukasz Szarpak, Tomasz Mazurek, Agnieszka Kapłon-Cieślicka, Grzegorz Opolski, Krzysztof J. Filipiak
    Academic press:
    Biology (rok: 2021, tom: 10, strony: 97), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/biology10020097 - link to the publication
  1. Circulating MicroRNAs and Platelet Extracellular Vesicles as Novel Biomarkers in Acute Ischaemic Stroke
    Authors:
    C. Eyileten, P. Czajka, D. Jakubik, J. Jarosz-Popek, Z. Fitas, A. Nowak, L. Zareba, G. von Baumgarten, S. De Rosa, A. Gasecka, M. Wolska, L. Sharif, D. Mirowska-Guzel, A. Czlonkowska, M. Postula
    Conference:
    International Society on Thrombosis and Haemostasis (rok: 2020, ), Wydawca: Research and Practice in Thrombosis and Haemostasis
    Data:
    konferencja 12-4 July
    Status:
    Published
  2. Platelet extracellular vesicles as first liquid biopsy biomarkers to diagnose acute ischaemic stroke
    Authors:
    Aleksandra Gasecka, Ceren Eyileten, Edwin van der Pol, Rienk Nieuwland, Krzysztof J. Filipiak, Marek Postula
    Conference:
    The International Society for Extracellular Vesicles 2019 (rok: 2019, ), Wydawca: Taylor & Francis Group
    Data:
    konferencja 24-28.04.2019
    Status:
    Published

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