Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Role of RNase activity of MCPIP1 protein in neuroblastoma suppression.

2017/25/N/NZ1/01254

Keywords:

cancer neuroblastoma inflammation MCPIP1 ribonuclease Akt/mTOR cell cycle

Descriptors:

  • NZ1_1: Molecular biology
  • NZ3_1: Cell biology
  • NZ1_2: Biochemistry

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Iwona Nowak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 13 - announced on 2017-03-15

Amount awarded: 141 480 PLN

Project start date (Y-m-d): 2018-01-30

Project end date (Y-m-d): 2021-01-29

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. MCPIP1 ribonuclease can bind and cleave AURKA mRNA in MYCN-amplified neuroblastoma cells
    Authors:
    Iwona Nowak, Elżbieta Boratyn, Sebastian Student, Stephan F Bernhart, Jörg Fallmann, Małgorzata Durbas, Peter F Stadler, Hanna Rokita
    Academic press:
    RNA biology (rok: 2021, tom: 18, strony: 144-156), Wydawca: Taylor and Francis Online
    Status:
    Published
    DOI:
    10.1080/15476286.2020.1804698. - link to the publication