Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Synthesis, toxicological and functional studies on mutli-walled carbon nanotubes as a scaffold for tissue engineering techniques in articular cartilage repair

2016/23/B/NZ7/01288

Keywords:

carbon nanotubes scaffold cell culture toxicology chondrocytes articular cartilage

Descriptors:

  • NZ7_15: Toxicology
  • ST5_10: Functional materials/nanomaterials, nanoparticles
  • NZ1_9: Biotechnology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Michał Giersig 

Number of co-investigators in the project: 7

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 1 774 199 PLN

Project start date (Y-m-d): 2017-07-03

Project end date (Y-m-d): 2022-06-02

Project duration:: 59 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Fluorymetr Qubit.
  2. Mieszadło Magnetyczne.
  3. MiniCentryfuga x6.
  4. pompa z akcesoriami QIAvac Plus.
  5. wilk do mięsa.
  6. Autoklaw Laboratoryjny.
  7. Mieszadło mechaniczne wraz ze statywami.
  8. Multi Vortex.
  9. Pompa (element składowy SNAP id).
  10. ThermoMixer.
  11. Piec do chemicznego osadzania z fazy gazowej (300 000 PLN)
  12. Termoblok x2.
  13. Drukarka SLA.
  14. Przystawka do ZetaPotencjału.
  15. SNAP i.d. 2.0.
  16. System Trans Turbo Blot.
  17. Pompa Perystaltyczna.

Information in the final report

  • Publication in academic press/journals (10)
  1. Carbon nanotubes interference with luminescence based assays
    Authors:
    T. Szymański, M. Kempa, M. Giersig and J.D. Rybka*;
    Academic press:
    MAterials (rok: 2020, tom: 13, strony: 4270), Wydawca: mdpi
    Status:
    Published
    DOI:
    doi:0.3390/ma13194270 - link to the publication
  2. Osteoarthritis Severely Decreases the Elasticity and Hardness of Knee Joint Cartilage: A Nanoindentation Study
    Authors:
    Adam Aron Mieloch , Magdalena Richter, Tomasz Trzeciak, Michael Giersig and Jakub Dalibor Rybka
    Academic press:
    Journal of Clinical MEdicine (rok: 2019, tom: 8, strony: 1865), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/jcm8111865 - link to the publication
  3. Radiosensitizing properties of magnetic hyperthermia mediated by superparamagnetic iron oxide nanoparticles (SPIONs) on human cutaneous melanoma cell lines
    Authors:
    Jakub Dalibor Rybka
    Academic press:
    reports of practical oncology and radiotherapy (rok: 2019, tom: 24, strony: 152-157), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.rpor.2019.01.002 - link to the publication
  4. Introduction to the state-of-the-art 3D bioprinting methods, design, and applications in orthopedics
    Authors:
    Julia Anna Semba, Adam Aron Mieloch, Jakub Dalibor Rybka
    Academic press:
    Bioprinting (rok: 2020, tom: 18, strony: 70), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.bprint.2019.e00070 - link to the publication
  5. Utilization of Carbon Nanotubes in Manufacturing of 3D Cartilage and Bone Scaffolds
    Authors:
    T. Szymanski, A.A. Mieloch, M. Richter, T. Trzeciak, E. Florek, J.D. Rybka*, M. Giersig;
    Academic press:
    Materials (rok: 2020, tom: 13, strony: 4039), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/ma13184039 - link to the publication
  6. Bioevaluation of superparamagnetic iron oxide nanoparticles (SPIONs) functionalized with dihexadecyl phosphate (DHP)
    Authors:
    A.A. Mieloch, M. Żurawek, M. Giersig, N. Rozwadowska and J.D.Rybka*
    Academic press:
    Scientific Reports (rok: 2020, tom: 10, strony: 2725), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-020-59478-2 - link to the publication
  7. Assembly and Characterization of HBc Derived Virus-like Particles with Magnetic Core
    Authors:
    Jakub Dalibor Rybka, Adam Mieloch, Alicja Plis, Marcin Pyrski, Tomasz Pniewski, Michał Giersig
    Academic press:
    nanomaterials (rok: 2019, tom: 9, strony: 155), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/nano9020155 - link to the publication
  8. Composite spheres made of bioengineered spider silk and iron oxide nanoparticles for theranostics applications
    Authors:
    Kamil Kucharczyk Jakub Dalibor Rybka, Michael Hilgendorff, Michal Krupinski, Mariusz Slachcinski, Andrzej Mackiewicz, Michael Giersig, Hanna Dams- Kozlowska
    Academic press:
    PLOS ONE (rok: 2019, tom: 14, strony: 7), Wydawca: PLOS ONE
    Status:
    Published
    DOI:
    10.1371/journal.pone.0219790 - link to the publication
  9. Parenteral–Oral Immunization with Plant-Derived HBcAg as a Potential Therapeutic Vaccine against Chronic Hepatitis B
    Authors:
    Marcin Pyrski, Adam Aron Mieloch, Adam Plewinski, Aneta Basinska-Barczak, Aleksandra Gryciuk, Piotr Bocia, MarekMurias, Jakub Dalibor Rybka and Tomasz Pniewski
    Academic press:
    vaccines (rok: 2019, tom: 7, strony: 211), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/vaccines7040211 - link to the publication
  10. Hyaluronic acid and multiwalled carbon nanotubes as bioink additives for cartilage tissue engineering
    Authors:
    Tomasz Szymański, Julia Anna Semba, Adam Aron Mieloch, Piotr Cywoniuk, Marcelina Kempa, Jakub Dalibor Rybka
    Academic press:
    Biomaterials Advances , Wydawca: Elsevier
    Status:
    Submitted