Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Synthesis, toxicological and functional studies on mutli-walled carbon nanotubes as a scaffold for tissue engineering techniques in articular cartilage repair

2016/23/B/NZ7/01288

Keywords:

carbon nanotubes scaffold cell culture toxicology chondrocytes articular cartilage

Descriptors:

  • NZ7_15: Toxicology
  • ST5_10: Functional materials/nanomaterials, nanoparticles
  • NZ1_9: Biotechnology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Michał Giersig 

Number of co-investigators in the project: 7

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 1 774 199 PLN

Project start date (Y-m-d): 2017-07-03

Project end date (Y-m-d): 2022-06-02

Project duration:: 59 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Drukarka SLA.
  2. Mieszadło mechaniczne wraz ze statywami.
  3. SNAP i.d. 2.0.
  4. Autoklaw Laboratoryjny.
  5. Mieszadło Magnetyczne.
  6. Piec do chemicznego osadzania z fazy gazowej (300 000 PLN)
  7. Pompa (element składowy SNAP id).
  8. Pompa Perystaltyczna.
  9. Termoblok x2.
  10. Multi Vortex.
  11. Przystawka do ZetaPotencjału.
  12. pompa z akcesoriami QIAvac Plus.
  13. wilk do mięsa.
  14. Fluorymetr Qubit.
  15. MiniCentryfuga x6.
  16. System Trans Turbo Blot.
  17. ThermoMixer.

Information in the final report

  • Publication in academic press/journals (10)
  1. Hyaluronic acid and multiwalled carbon nanotubes as bioink additives for cartilage tissue engineering
    Authors:
    Tomasz Szymański, Julia Anna Semba, Adam Aron Mieloch, Piotr Cywoniuk, Marcelina Kempa, Jakub Dalibor Rybka
    Academic press:
    Biomaterials Advances , Wydawca: Elsevier
    Status:
    Submitted
    DOI:
    brak - link to the publication
  2. Carbon nanotubes interference with luminescence based assays
    Authors:
    T. Szymański, M. Kempa, M. Giersig and J.D. Rybka*;
    Academic press:
    MAterials (rok: 2020, tom: 13, strony: 4270), Wydawca: mdpi
    Status:
    Published
    DOI:
    doi:0.3390/ma13194270 - link to the publication
  3. Composite spheres made of bioengineered spider silk and iron oxide nanoparticles for theranostics applications
    Authors:
    Kamil Kucharczyk Jakub Dalibor Rybka, Michael Hilgendorff, Michal Krupinski, Mariusz Slachcinski, Andrzej Mackiewicz, Michael Giersig, Hanna Dams- Kozlowska
    Academic press:
    PLOS ONE (rok: 2019, tom: 14, strony: 7), Wydawca: PLOS ONE
    Status:
    Published
    DOI:
    10.1371/journal.pone.0219790 - link to the publication
  4. Introduction to the state-of-the-art 3D bioprinting methods, design, and applications in orthopedics
    Authors:
    Julia Anna Semba, Adam Aron Mieloch, Jakub Dalibor Rybka
    Academic press:
    Bioprinting (rok: 2020, tom: 18, strony: 70), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.bprint.2019.e00070 - link to the publication
  5. Osteoarthritis Severely Decreases the Elasticity and Hardness of Knee Joint Cartilage: A Nanoindentation Study
    Authors:
    Adam Aron Mieloch , Magdalena Richter, Tomasz Trzeciak, Michael Giersig and Jakub Dalibor Rybka
    Academic press:
    Journal of Clinical MEdicine (rok: 2019, tom: 8, strony: 1865), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/jcm8111865 - link to the publication
  6. Utilization of Carbon Nanotubes in Manufacturing of 3D Cartilage and Bone Scaffolds
    Authors:
    T. Szymanski, A.A. Mieloch, M. Richter, T. Trzeciak, E. Florek, J.D. Rybka*, M. Giersig;
    Academic press:
    Materials (rok: 2020, tom: 13, strony: 4039), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/ma13184039 - link to the publication
  7. Assembly and Characterization of HBc Derived Virus-like Particles with Magnetic Core
    Authors:
    Jakub Dalibor Rybka, Adam Mieloch, Alicja Plis, Marcin Pyrski, Tomasz Pniewski, Michał Giersig
    Academic press:
    nanomaterials (rok: 2019, tom: 9, strony: 155), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/nano9020155 - link to the publication
  8. Bioevaluation of superparamagnetic iron oxide nanoparticles (SPIONs) functionalized with dihexadecyl phosphate (DHP)
    Authors:
    A.A. Mieloch, M. Żurawek, M. Giersig, N. Rozwadowska and J.D.Rybka*
    Academic press:
    Scientific Reports (rok: 2020, tom: 10, strony: 2725), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-020-59478-2 - link to the publication
  9. Parenteral–Oral Immunization with Plant-Derived HBcAg as a Potential Therapeutic Vaccine against Chronic Hepatitis B
    Authors:
    Marcin Pyrski, Adam Aron Mieloch, Adam Plewinski, Aneta Basinska-Barczak, Aleksandra Gryciuk, Piotr Bocia, MarekMurias, Jakub Dalibor Rybka and Tomasz Pniewski
    Academic press:
    vaccines (rok: 2019, tom: 7, strony: 211), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/vaccines7040211 - link to the publication
  10. Radiosensitizing properties of magnetic hyperthermia mediated by superparamagnetic iron oxide nanoparticles (SPIONs) on human cutaneous melanoma cell lines
    Authors:
    Jakub Dalibor Rybka
    Academic press:
    reports of practical oncology and radiotherapy (rok: 2019, tom: 24, strony: 152-157), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.rpor.2019.01.002 - link to the publication

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