Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Involvement of P2 receptors in pathogenesis of glomerular filtration barrier dysfunction in experimental model of diabetes type 1

2016/23/B/NZ5/02632

Keywords:

diabetes glomerulopathy receptors P2

Descriptors:

  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Maciej Jankowski 

Number of co-investigators in the project: 6

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 788 340 PLN

Project start date (Y-m-d): 2017-07-18

Project end date (Y-m-d): 2021-07-17

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Detektor fluorescencyjny do przezskórnego pomiaru GFR z oprogramowaniem (18 000 PLN)
  2. Laboratoryjna zamrażarka niskotemperaturowa (45 000 PLN)
  3. Pompa infuzyjna strzykawkowa dwukierunkowa (16 000 PLN)
  4. Mikroskop fluorescencyjny odwrócony z oprogramowaniem umożliwiającym selekcję, detekcję i analizę obrazów fluorescencyjnych (200 000 PLN)
  5. System do termostabilizacji perfuzatu i środowiska inkubacyjnego.

Information in the final report

  • Publication in academic press/journals (3)
  1. Effect of suramin on urinary excretion of diabetes-induced glomerular and tubular injury parameters in rats
    Authors:
    Kornelia Sałaga-Zaleska, Piotr Pikul, Ewelina Kreft, Sylwia Herman, Gabriela Chyła, Kamil Dąbkowski, Agnieszka Kuchta, Małgorzata Lenartowicz, Maciej Jankowski
    Academic press:
    Biomedicine & Pharmacotherapy (rok: 2021, tom: 139, strony: 111683), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.biopha.2021.111683 - link to the publication
  2. Diabetes Affects the A1 Adenosine Receptor-Dependent Action of Diadenosine Tetraphosphate (Ap4A) on Cortical and Medullary Renal Blood Flow
    Authors:
    Ewelina Kreft, Kornelia Sałaga-Zalesk, Monika Sakowicz-Burkiewicz, Kamil Dąbkowsk, Miroslawa Szczepánska-Konkel , Maciej Jankowski
    Academic press:
    Journal of Vascular Research (rok: 2021, tom: 58, strony: 38–48), Wydawca: Karger AG Basel
    Status:
    Published
    DOI:
    10.1159/000511461 - link to the publication
  3. Suramin enhances the urinary excretion of VEGF‑A in normoglycemic and streptozotocin‑induced diabetic rats
    Authors:
    Gabriela Chyła, Kornelia Sałaga‑Zaleska, Kamil Dąbkowski, Agnieszka Kuchta, Maciej Jankowski
    Academic press:
    Pharmacological Reports (rok: 2021, tom: 73, strony: 841-846), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s43440-021-00236-0 - link to the publication