Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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A comprehensive assessment of fibrin clot properties in patients with aortic stenosis - involvement of fibrinogen oxidation in the severity of aortic stenosis

2016/21/N/NZ5/00512

Keywords:

aortic stenosis fibrin clot properties fibrinogen oxidation

Descriptors:

  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Krakowski Szpital Specjalistyczny im. Jana Pawła II

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Jakub Siudut 

Number of co-investigators in the project: 3

Call: PRELUDIUM 11 - announced on 2016-03-15

Amount awarded: 149 940 PLN

Project start date (Y-m-d): 2017-02-27

Project end date (Y-m-d): 2021-08-26

Project duration:: 54 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. GraphPad Prism 7 (3 900 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Apolipoproteins and lipoprotein(a) as factors modulating fibrin clot properties in patients with severe aortic stenosis
    Authors:
    Jakub Siudut, Joanna Natorska, Ewa Wypasek, Łukasz Wiewiórka, Elżbieta Ostrowska-Kaim, Sylwia Wiśniowska-Śmiałek, Krzysztof Plens, Piotr Musialek, Jacek Legutko, Anetta Undas
    Academic press:
    Atherosclerosis , Wydawca: Elsevier B.V.
    Status:
    Accepted for publication
    DOI:
    brak - link to the publication
  2. Determinants of plasma fibrin clot lysis measured using three different assays in healthy subjects
    Authors:
    Jakub Siudut, Teresa Iwaniec, Krzysztof Plens, Marlien Pieters, Anetta Undas
    Academic press:
    Thrombosis Research (rok: 2021, tom: 197, strony: 45298), Wydawca: Elsevier B.V.
    Status:
    Published
    DOI:
    10.014 - link to the publication
  3. Impaired Fibrinolysis in Patients with Isolated Aortic Stenosis is Associated with Enhanced Oxidative Stress
    Authors:
    Jakub Siudut, Joanna Natorska, Ewa Wypasek, Łukasz Wiewiórka, Elżbieta Ostrowska-Kaim, Sylwia Wiśniowska-Śmiałek, Krzysztof Plens, Jacek Legutko, Anetta Undas
    Academic press:
    Journal of Clinical Medicine (rok: 2020, tom: 9, strony: 2002), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jcm9062002 - link to the publication

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