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Polymorphisms of miRNA genes and in the 3'UTR region of the ADME genes in breast cancer patients treated with FAC (5-fluorouracil, doxorubicyn, cyclophosphamide) chemotherapy.

2016/21/D/NZ5/01913

Keywords:

drug resistance breast cancer 5-fluorouracil doxorubicyne cyclophosphamide ADME proceses miRNA

Descriptors:

  • NZ5_1: Etiology of human diseases
  • NZ5_7: Human disease treatment
  • NZ5_9: Other related subjects

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Jolanta Pamuła-Piłat 

Number of co-investigators in the project: 3

Call: SONATA 11 - announced on 2016-03-15

Amount awarded: 452 300 PLN

Project start date (Y-m-d): 2017-02-23

Project end date (Y-m-d): 2021-10-22

Project duration:: 56 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. Are the common genetic 3'UTR variants in ADME genes playing a role in tolerance of breast cancer chemotherapy?
    Authors:
    Karolina Tęcza, Magdalena Kalinowska-Herok, Joanna Łanuszewska, Jolanta Pamuła-Piłat
    Academic press:
    Scientific Reports , Wydawca: Nature Research
    Status:
    Submitted
    DOI:
    brak - link to the publication
  2. Genetic 3′UTR variations and clinical factors significantly contribute to survival prediction and clinical response in breast cancer patients
    Authors:
    Jolanta Pamuła-Piłat, Karolina Tęcza, Magdalena Kalinowska-Herok, Ewa Grzybowska
    Academic press:
    Scientific Reports (rok: 2020, tom: 10, strony: -), Wydawca: Nature Research
    Status:
    Published
    DOI:
    10.1038/s41598-020-62662-z - link to the publication

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