Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Role of apelin and chemerin in selected aspects of ovarian cancer progression using two- and three-dimensional model in vitro.

2016/21/N/NZ5/00161

Keywords:

apelin chemerin IGF1 E2 proliferation apoptosis ovarian cancer

Descriptors:

  • NZ5_9: Other related subjects
  • NZ4_6: Endocrinology
  • NZ3_1: Cell biology

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Jagielloński, Wydział Biologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Marta Hoffmann 

Number of co-investigators in the project: 2

Call: PRELUDIUM 11 - announced on 2016-03-15

Amount awarded: 99 996 PLN

Project start date (Y-m-d): 2017-03-21

Project end date (Y-m-d): 2019-03-20

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (1)
  1. Apelin abrogates the stimulatory effects of 17β-estradiol and insulin-like growth factor-1 on proliferation of epithelial and granulosa ovarian cancer cell lines via crosstalk between APLNR and ERα/IGF1R
    Authors:
    Marta Hoffmann, Justyna Gogola, Anna Ptak
    Academic press:
    Molecular Biology Reports (rok: 2019, tom: 46, strony: 6325-6338), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s11033-019-05073-2 - link to the publication
  1. 17 β-estradiol reverses apelin-inducing ovarian cancer cell proliferation
    Authors:
    Hoffmann Marta, Gogola Justyna, Ptak Anna
    Conference:
    New Insights in Rare Gynaecological Malignancies - ESGO State of the Art Conference 2018 (rok: 2018, ), Wydawca: BMJ Journals
    Data:
    konferencja 4-6 październik
    Status:
    Published