Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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The role of oxidative stress biomarkers, pro-inflammatory, neuroendocrine and genetic factors, body composition evaluated with the use of DXA method, and brain metabolism in pathogenesis of delirium after cardiac surgery, their predictive value and the impact on prognosis.

2016/21/B/NZ5/00495

Keywords:

delirium cardiac surgery oxidative stress pro-inflammatory factors DXA PET

Descriptors:

  • NZ5_1: Etiology of human diseases
  • NZ5_3: Pathogenesis of human diseases
  • NZ5_5: Diagnostics in human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu, Klinika Psychiatrii Wieku Podeszłego i Zaburzeń Psychotycznych

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Jakub Kaźmierski 

Number of co-investigators in the project: 3

Call: OPUS 11 - announced on 2016-03-15

Amount awarded: 732 420 PLN

Project start date (Y-m-d): 2017-03-02

Project end date (Y-m-d): 2022-03-01

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Elevated monocyte chemoattractant protein-1 as the independent risk factor of delirium after cardiac surgery. A prospective cohort study
    Authors:
    Jakub Kaźmierski, Piotr Miler, Agnieszka Pawlak, Hanna Jerczyńska, Joanna Woźniak, Emilia Frankowska, Agnieszka Brzezińska, Katarzyna Woźniak, Michał Krejca and Mirosław Wilczyński.
    Academic press:
    Journal of Clinical Medicine (rok: 2021, tom: 10, strony: 1587), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jcm10081587 - link to the publication
  2. Lower preoperative verbal memory performance is associated with delirium after coronary artery bypass graft surgery: a prospective cohort study
    Authors:
    Jakub Kaźmierski, Piotr Miler, Agnieszka Pawlak, Joanna Woźniak, Emilia Frankowska, Karina Nowakowska, Katarzyna Kuchta, Michał Pazdrak, Katarzyna Woźniak, Radosław Magierski, Michał Krejca, Mirosław Wilczyński,
    Academic press:
    Archives of Clinical Neuropsychology (rok: 2022, tom: -, strony: -), Wydawca: Oxford Academic. Artykuł przyjęty do publikacji.
    Status:
    Accepted for publication
  3. Increased postoperative myeloperoxidase concentration associated with low baseline antioxidant capacity as the risk factor of delirium after cardiac surgery
    Authors:
    Jakub Kazmierski, Piotr Miler, Agnieszka Pawlak, Hanna Jerczynska, Karina Nowakowska, Grzegorz Walkiewicz, Katarzyna Wozniak, Michał Krejca and Mirosław Wilczynski
    Academic press:
    Annals of Medicine (rok: 2022, tom: 54, strony: 610-616), Wydawca: Taylor & Francis
    Status:
    Published
    DOI:
    10.1080/07853890.2022.2039405 - link to the publication
  4. Oxidative stress and soluble receptor for advanced glycation end‑products play a role in the pathophysiology of delirium after cardiac surgery
    Authors:
    Jakub Kaźmierski, Piotr Miler, Agnieszka Pawlak, Hanna Jerczyńska, Joanna Woźniak, Emilia Frankowska, Agnieszka Brzezińska, Karina Nowakowska, Katarzyna Woźniak, Michał Krejca & Mirosław Wilczyński
    Academic press:
    Scientific Reports (rok: 2021, tom: 11, strony: -), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-021-03007-2 - link to the publication