The role of oxidative stress biomarkers, pro-inflammatory, neuroendocrine and genetic factors, body composition evaluated with the use of DXA method, and brain metabolism in pathogenesis of delirium after cardiac surgery, their predictive value and the impact on prognosis.

2016/21/B/NZ5/00495

Keywords

Descriptors

  • NZ5_1: Etiologia chorób człowieka
  • NZ5_3: Patogeneza chorób człowieka
  • NZ5_5: Diagnostyka chorób człowieka

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu, Klinika Psychiatrii Wieku Podeszłego i Zaburzeń Psychotycznych

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Jakub Michał Kaźmierski

Number of co-investigators in the project: 3

Call

OPUS 11 – announced on 2016-03-15

Amount awarded
732 420 PLN
Project start date
2017-03-02
Project end date
2022-03-01
Project duration
60 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (4)

  1. Increased postoperative myeloperoxidase concentration associated with low baseline antioxidant capacity as the risk factor of delirium after cardiac surgery

    Authors:
    Jakub Kazmierski, Piotr Miler, Agnieszka Pawlak, Hanna Jerczynska, Karina Nowakowska, Grzegorz Walkiewicz, Katarzyna Wozniak, Michał Krejca and Mirosław Wilczynski
    Academic press:
    Annals of Medicine (year: 2022, volume: 54, pages: 610-616), Publisher: Taylor & Francis
    Status:
    Published
    DOI:
    10.1080/07853890.2022.2039405 – link to the publication
  2. Elevated monocyte chemoattractant protein-1 as the independent risk factor of delirium after cardiac surgery. A prospective cohort study

    Authors:
    Jakub Kaźmierski, Piotr Miler, Agnieszka Pawlak, Hanna Jerczyńska, Joanna Woźniak, Emilia Frankowska, Agnieszka Brzezińska, Katarzyna Woźniak, Michał Krejca and Mirosław Wilczyński.
    Academic press:
    Journal of Clinical Medicine (year: 2021, volume: 10, pages: 1587), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/jcm10081587 – link to the publication
  3. Oxidative stress and soluble receptor for advanced glycation end‑products play a role in the pathophysiology of delirium after cardiac surgery

    Authors:
    Jakub Kaźmierski, Piotr Miler, Agnieszka Pawlak, Hanna Jerczyńska, Joanna Woźniak, Emilia Frankowska, Agnieszka Brzezińska, Karina Nowakowska, Katarzyna Woźniak, Michał Krejca & Mirosław Wilczyński
    Academic press:
    Scientific Reports (year: 2021, volume: 11, pages: -), Publisher: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-021-03007-2 – link to the publication
  4. Lower preoperative verbal memory performance is associated with delirium after coronary artery bypass graft surgery: a prospective cohort study

    Authors:
    Jakub Kaźmierski, Piotr Miler, Agnieszka Pawlak, Joanna Woźniak, Emilia Frankowska, Karina Nowakowska, Katarzyna Kuchta, Michał Pazdrak, Katarzyna Woźniak, Radosław Magierski, Michał Krejca, Mirosław Wilczyński,
    Status:
    Accepted for publication

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