Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Copper induced Ab aggregation upon synaptic excitation. Reaction - diffusion simulations in realistic 3D reconstruction of the synaptic cleft

2015/19/N/NZ1/02021

Keywords:

synapse beta amyloid Cu(II) Alzheimer simulations Monte Carlo

Descriptors:

  • ST6_12: Scientific computing, simulation and modelling tools
  • NZ3_5: Molecular neurobiology
  • NZ1_3: Biophysics

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Wojciech Goch 

Number of co-investigators in the project: 2

Call: PRELUDIUM 10 - announced on 2015-09-15

Amount awarded: 38 560 PLN

Project start date (Y-m-d): 2016-06-14

Project end date (Y-m-d): 2017-06-13

Project duration:: 12 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Wolfram Mathematica 10 (4 747 PLN)
  2. Laptop (3 500 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  1. Numerical Simulations Reveal Randomness of Cu(II) Induced Aβ Peptide Dimerization under Conditions Present in Glutamatergic Synapses
    Authors:
    Wojciech Goch, Wojciech Bal
    Academic press:
    PLOS ONE (rok: 2017, tom: 12 (1), strony: nie dotyczy), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0170749 - link to the publication