Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Studies of the permeation of anthocyanins and their metabolites through the brain barriers in the context of the preventive strategies of neurodegenerative diseases

2015/17/B/NZ9/01733

Keywords:

brain barriers cerebrospinal fluid anthocyanins cyanidin metabolites protocatechuic acid chokeberry red cabbage prevention central nervous system diseases

Descriptors:

  • NZ9_7: Nutrition and food sciences
  • NZ9_13: Other related subjects

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Instytut Rozrodu Zwierząt i Badań Żywności PAN

woj. warmińsko-mazurskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Wiesław Wiczkowski 

Number of co-investigators in the project: 11

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 699 900 PLN

Project start date (Y-m-d): 2016-02-15

Project end date (Y-m-d): 2020-02-14

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Chokeberry anthocyanins and their metabolites ability to cross the blood-cerebrospinal fluid barrier
    Authors:
    Natalia PŁATOSZ, Natalia BĄCZEK, Joanna TOPOLSKA, Dorota SZAWARA-NOWAK, Janina SKIPOR, Stanisław MILEWSKI, Wiesław WICZKOWSKI
    Academic press:
    Food Chemistry (rok: 2021, tom: 346, strony: nr art. 128730, 1-11), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.foodchem.2020.128730 - link to the publication
  2. The Blood−Cerebrospinal Fluid Barrier Is Selective for Red Cabbage Anthocyanins and Their Metabolites
    Authors:
    Natalia Płatosz, Natalia Bączek, Joanna Topolska, Dorota Szawara-Nowak, Tomasz Misztal, Wiesław Wiczkowski
    Academic press:
    Journal of Agricultural and Food Chemistry (rok: 2020, tom: 68, strony: 8274-8285), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acs.jafc.0c03170 - link to the publication
  3. The blood-cerebrospinal fluid barrier features different permeability to cyanidin-3-galactoside and cyanidin-3-diglucoside-5-glucoside and their metabolites circulating in blood
    Authors:
    Natalia Płatosz, Natalia Bączek, Joanna Topolska, Dorota Szawara-Nowak, Wiesław Wiczkowski
    Academic press:
    Journal of Agricultural and Food Chemistry (rok: 2022, ), Wydawca: ACS Publications
    Status:
    Accepted for publication
    DOI:
    10.1021/acs.jafc.2c03778 - link to the publication