Projects funded by the NCN
The influence of tauroursodeoxycholic acid (TUDCA) on the reduction of ER stress in chondrocyte cells - as a new direction in cartilage functioning improvement
2015/17/N/NZ7/01094
Keywords:
chondrocytes ER stress hypoxia TUDCA
Descriptors:
- NZ7_14: Pharmacy, pharmacotherapy, pharmacology
- NZ5_7: Human disease treatment
- NZ7_12: Prevention of human diseases
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej
woj. podlaskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 3
Call: PRELUDIUM 9 - announced on 2015-03-16
Amount awarded: 149 760 PLN
Project start date (Y-m-d): 2016-03-16
Project end date (Y-m-d): 2019-09-15
Project duration:: 42 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- Molecular and Cellular Effects of Chemical Chaperone—TUDCA on ER-Stressed NHAC-kn Human Articular Chondrocytes Cultured in Normoxic and Hypoxic ConditionsAuthors:Kusaczuk M., Naumowicz M., Krętowski R., Cukierman B.. Cechowska-Pasko M.Academic press:Molecules (rok: 2021, tom: 26(4): 878, strony: 878), Wydawca: mdpiStatus:PublishedDOI:10.3390/molecules26040878 - link to the publication
- Tauroursodeoxycholate—Bile Acid with Chaperoning Activity: Molecular and Cellular Effects and Therapeutic PerspectivesAuthors:Kusaczuk M.Academic press:Cells (rok: 2019, tom: 8(12): 1471., strony: 1471), Wydawca: mdpiStatus:PublishedDOI:10.3390/cells8121471 - link to the publication