Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Investigation of the relationship between telomerase activity and the mechanism of cell death induction in head and neck squamous cell carcinoma.

2015/17/N/NZ5/00686

Keywords:

telomerase squamous cell carcinoma lentivirus

Descriptors:

  • NZ5_4: Pathogenesis of animal diseases
  • NZ5_7: Human disease treatment

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski II

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Wojciech Barczak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 9 - announced on 2015-03-16

Amount awarded: 147 600 PLN

Project start date (Y-m-d): 2016-03-14

Project end date (Y-m-d): 2019-03-13

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. zestaw pipet z pipetą wielokanałową (3 600 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  1. RNA interference in head and neck oncology
    Authors:
    Sobecka A, Barczak W, Suchorska W
    Academic press:
    Oncology Letters (rok: 2016, tom: 12, strony: 3035-3040), Wydawca: Spandidos Publications
    Status:
    Published
    DOI:
    10.1007/s12033-014-9815-4 - link to the publication
  2. hTERT gene knockdown enhances response to radio- and chemotherapy in head and neck cancer cell lines through a DNA damage pathway modification
    Authors:
    Barczak W, Sobecka A, Golusinski P, Masternak MM, Rubis B, Suchorska WM, Golusinski W
    Academic press:
    Scientific Reports (rok: 2018, tom: 8, strony: 5949), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-018-24503-y - link to the publication
  3. hTERT promoter methylation status in peripheral blood leukocytes as a molecular marker of head and neck cancer progression
    Authors:
    Sobecka A, Błaszczak W, Barczak W, Golusinski P, Rubis B, Masternak MM, Suchorska WM, Golusinski W
    Academic press:
    Journal of Applied Genetics (rok: 2018, tom: 58, strony: 453–461), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s13353-018-0458-1 - link to the publication
  4. Clinical value of monoclonal antibodies and tyrosine kinase inhibitors in the treatment of head and neck squamous cell carcinoma
    Authors:
    Wiktoria Blaszczak, Wojciech Barczak, Anna Wegner, Wojciech Golusinski, Wiktoria Maria Suchorska
    Academic press:
    Medical Oncology (rok: 2017, tom: 34(4), strony: 60), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12032-017-0918-1 - link to the publication
  5. hTERT C250T promoter mutation and telomere length as a molecular markers of cancer progression in patients with head and neck cancer
    Authors:
    Barczak W, Suchorska WM, Sobecka A, Bednarowicz K, Machczynski P, Golusinski P, Rubis B, Masternak MM, Golusinski W
    Academic press:
    Molecular Medicine Reports (rok: 2017, tom: 16(1), strony: 441-446), Wydawca: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/mmr.2017.6590 - link to the publication
  6. Association of DNA repair genes polymorphisms and mutations with increased risk of head and neck cancer: a review
    Authors:
    Agata Dylawerska, Wojciech Barczak Anna Wegner, Wojciech Golusinski, Wiktoria Maria Suchorska
    Academic press:
    Medical Oncology (rok: 2017, tom: 34(12), strony: 197), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12032-017-1057-4 - link to the publication

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