Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Cellular and molecular mechanisms in pathology of post-inflammatory myocardial fibrosis

2014/14/E/NZ5/00175

Keywords:

myocarditis myocardial fibrosis myofibroblasts heart failure

Descriptors:

  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Przemysław Błyszczuk 

Number of co-investigators in the project: 5

Call: SONATA BIS 4 - announced on 2014-06-16

Amount awarded: 1 999 693 PLN

Project start date (Y-m-d): 2015-08-12

Project end date (Y-m-d): 2021-08-11

Project duration:: 72 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zestaw komputerowy wraz z oprogramowaniem (3 szt.) (18 000 PLN)
  2. Drukarka laserowa (1 500 PLN)
  3. Inkubator do hodowli komórkowych (39 000 PLN)
  4. Ultrawirówka do 100 000 g (250 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  • Articles in post-conference publications (1)
  1. WNT/β-catenin signaling promotes TGF-β-mediated activation of human cardiac fibroblasts by enhancing IL-11 production
    Authors:
    Działo E, Czepiel M, Tkacz K, Siedlar M, Kania G, Błyszczuk P
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22(18), strony: 45307), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms221810072 - link to the publication
  2. Myocarditis in Humans and in Experimental Animal Models
    Authors:
    Przemysław Błyszczuk
    Academic press:
    Frontiers in Cardiovascular Medicine (rok: 2019, tom: 6, strony: 45308), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fcvm.2019.00064 - link to the publication
  3. WNT3a and WNT5a Transported by Exosomes Activate WNT Signaling Pathways in Human Cardiac Fibroblasts
    Authors:
    Dzialo E, Rudnik M, Koning RI, Czepiel M, Tkacz K, Baj-Krzyworzeka M, Distler O, Siedlar M, Kania G, Blyszczuk P.
    Academic press:
    International Journal of Molecular Sciences (rok: 2019, tom: 20, strony: 45306), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20061436 - link to the publication
  4. Crosstalk between the TGF-β and WNT signalling pathways during cardiac fibrogenesis
    Authors:
    Edyta Działo, Karolina Tkacz, Przemysław Błyszczuk
    Academic press:
    Acta Biochimica Polonica (rok: 2018, tom: Vol 65 No 3, strony: 341-349), Wydawca: Polskie Towarzystwo Biochemiczne i Komitet Biochemii i Biofizyki PAN
    Status:
    Published
    DOI:
    10.18388/abp.2018_2635 - link to the publication
  5. Haploinsufficient Rock1+/- and Rock2+/- Mice Are Not Protected from Cardiac Inflammation and Postinflammatory Fibrosis in Experimental Autoimmune Myocarditis
    Authors:
    Tkacz K, Rolski F, Czepiel M, Działo E, Siedlar M, Eriksson U, Kania G, Błyszczuk P
    Academic press:
    Cells (rok: 2020, tom: 9, strony: 45307), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells9030700 - link to the publication
  6. Angiotensin II receptor 1 controls profibrotic Wnt/β-catenin signalling in experimental autoimmune myocarditis
    Authors:
    Czepiel M, Diviani D, Jaźwa-Kusior A , Tkacz K, Rolski F, Smolenski RT, Siedlar M, Eriksson U, Kania G , Błyszczuk P
    Academic press:
    Cardiovascular Research (rok: 2022, tom: 118(2), strony: 573-584), Wydawca: Oxford Academic
    Status:
    Published
    DOI:
    10.1093/cvr/cvab039 - link to the publication
  1. Role of angiotensin II receptor type 1 in TGF-beta-mediated fibrogenesis in mouse model of experimental autoimmune myocarditis
    Authors:
    M. Czepiel G. Kania D. Diviani O. Diestler U. Eriksson M. Siedlar P. Blyszczuk
    Conference:
    ESC Congress 2017 (rok: 2017, ), Wydawca: European Heart Journal
    Data:
    konferencja 26-30 August
    Status:
    Published
    DOI:
    link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy