Searching for novel mechanisms of gene expression regulation, independent from RNAi pathway - short RNAs derived from snoRNAs.

2014/13/D/NZ1/00061

Keywords

Descriptors

  • NZ1_2: Biochemia
  • NZ1_1: Biologia molekularna

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Instytut Chemii Bioorganicznej PAN

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Kamilla Bąkowska-Żywicka

Number of co-investigators in the project: 4

Call

SONATA 7 – announced on 2014-03-17

Amount awarded
631 840 PLN
Project start date
2015-01-22
Project end date
2018-01-21
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Inkubator z wytrząsaniem.
  2. zestaw komputerowy. Cost: 5 500 PLN

Information in the final report

Publication in academic press/journals (4)

  1. tRNA-derived short RNAs bind to Saccharomyces cerevisiae ribosomes in a stress-dependent manner and inhibit protein synthesis in vitro

    Authors:
    K. Bąkowska-Żywicka, M. Kasprzyk, T. Twardowski
    Academic press:
    FEMS Yeast Research (year: 2016, volume: 16(6), pages: fow077), Publisher: Oxford Academic
    Status:
    Published
    DOI:
    10.1093/femsyr/fow077 – link to the publication
  2. The widespread occurrence of tRNA-derived fragments in Saccharomyces cerevisiae

    Authors:
    K. Bąkowska-Żywicka, A. M. Mleczko, M. Kasprzyk, P. Machtel, M. Żywicki, T. Twardowski
    Academic press:
    FEBS Open Bio (year: 2016, volume: 6 (21), pages: 1186-1200), Publisher: FEBS Press
    Status:
    Published
    DOI:
    10.1002/2211-5463.12127 – link to the publication
  3. Evaluation of methods for detection of low-abundant snoRNA-derived small RNAs in Saccharomyces cerevisiae

    Authors:
    M. Walkowiak, A.M. Mleczko, K. Bąkowska-Żywicka
    Academic press:
    BioTechnologia (year: 2016, volume: 97, pages: 19-26), Publisher: Institute of Bioorganic Chemistry, Polish Academy of Sciences
    Status:
    Published
    DOI:
    10.5114/bta.2016.58540 – link to the publication
  4. When small RNAs become smaller: non - canonical functions of snoRNAs and their derivatives

    Authors:
    A.M. Mleczko, K. Bąkowska-Żywicka
    Academic press:
    Acta Biochimica Polonica (year: 2016, volume: 63(4), pages: 601-607), Publisher: Polskie Towarzystwo Biochemiczne
    Status:
    Published
    DOI:
    10.18388/abp.2016_1330 – link to the publication

Book publications / chapters in book publications (2)

  1. Na co chorują drożdże – modelowanie chorób człowieka w Saccharomyces cerevisiae

    Authors:
    M. Walkowiak, K. Bąkowska-Żywicka
    Book:
    Postęp medycyny w leczeniu i ochronie zdrowia (year: 2016, volume: II, pages: 55-66), Publisher: Wydawnictwo Naukowe TYGIEL sp. Z o. o.
    Status:
    Published
  2. Stress Responsive Non-protein Coding RNAs

    Authors:
    A.Tyczewska, K. Bąkowska-Żywicka, J. Gracz, T. Twardowski
    Book:
    Abiotic and Biotic Stress in Plants - Recent Advances and Future Perspectives (year: 2016, volume: 7, pages: 153-181), Publisher: InTech
    Status:
    Published

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Graphic design and implementation: Jakub Piotrowski