Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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New nanocarriers of curcumin as a kind of "pro-drug" - physicochemical characteristics and biological characteristics on in vivo models.

2013/09/N/ST5/02488

Keywords:

curcumin polymer conjugate chondroitin sulfate carboxymethylcellulose poly(D,L-lactide)

Descriptors:

  • ST5_21:
  • ST5_12: Methods of nanomaterials/materials synthesis
  • ST5_10: Functional materials/nanomaterials, nanoparticles

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Jagielloński, Wydział Chemii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Dorota Lachowicz 

Number of co-investigators in the project: 2

Call: PRELUDIUM 5 - announced on 2013-03-15

Amount awarded: 100 000 PLN

Project start date (Y-m-d): 2014-03-25

Project end date (Y-m-d): 2016-03-24

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Eksykator próżniowy (3 000 PLN)
  2. Elektroda zespolona dla pomiarów pH (500 PLN)
  3. Zanurzeniowy czujnik konduktometryczny CD-2 (500 PLN)
  4. Łaźnia ultradźwiękowa (2 340 PLN)
  5. Mieszadło magnetyczne z systemem grzewczym (5 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Biocompatible and fluorescent superparamagnetic iron oxide nanoparticles with superior magnetic properties coated with charged polysaccharide derivatives
    Authors:
    D. Lachowicz, A. Szpak, K.E. Malek-Zietek, M. Kepczynski, R. N. Muller, S.Laurent, M. Nowakowska, S. Zapotoczny
    Academic press:
    Colloids and Surfaces B (rok: 2017, tom: 150, strony: 402-407), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.colsurfb.2016.11.003 - link to the publication
  2. A Hybrid System for Magnetic Hyperthermia and Drug Delivery: SPION Functionalized by Curcumin Conjugate
    Authors:
    Dorota Lachowicz,Agnieszka Kaczyńska, Roma Wirecka, Angelika Kmita, Wojciech Szczerba, Anna Bodzoń-Kułakowska, Marcin Sikora, Anna Karewicz, Szczepan Zapotoczny
    Academic press:
    Materials (rok: 2018, tom: 11(12), strony: 2388 (1-17)), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma11122388 - link to the publication
  3. Blood-compatible, stable micelles of sodium alginate - curcumin bioconjugate for anti-cancer applications
    Authors:
    Dorota Lachowicz, Michał Szuwarzyński, Alicja Karabasz, Maria Nowakowska, Monika Bzowska,Anna Karewicz
    Academic press:
    European Polymer Journal (rok: 2019, tom: 113, strony: 208-219), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.eurpolymj.2019.01.058 - link to the publication

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