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Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Evolution of MHC copy number: a test of optimality hypohesis and the analysis of alternatives

2013/08/A/NZ8/00153

Keywords:

Major histocompatibility complex immune response host-parasite coevolutoin mate choice

Descriptors:

  • NZ8_1: Evolutionary biology

Panel:

NZ8 - Evolutionary and environmental biology: evolution, ecology, population biology, biodiversity, biogeography

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jacek Radwan 

Number of co-investigators in the project: 5

Call: MAESTRO 4 - announced on 2012-12-15

Amount awarded: 2 282 500 PLN

Project start date (Y-m-d): 2013-09-26

Project end date (Y-m-d): 2018-09-25

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Szprzęt komputerowy z oprogramowaniem (54 000 PLN)
  2. Średnioprzepustowy sekwenator nowej generacji (500 000 PLN)
  3. zamrażarka (6 000 PLN)

Information in the final report

  • Publication in academic press/journals (7)
  1. De novo transcriptome assembly facilitates characterisation of fast-evolving gene families, MHC class I in the bank vole (Myodes glareolus)
    Authors:
    M Migalska, A Sebastian, M Konczal, P Kotlík, J Radwan
    Academic press:
    Heredity (rok: 2017, tom: 118, strony: 348–357), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/hdy.2016.105 - link to the publication
  2. Major histocompatibility complex class I diversity limits repertoire of T-cell receptors
    Authors:
    Migalska M., Sebastian A., Radwan J.
    Academic press:
    PNAS (rok: 2019, tom: 116(11), strony: 5021–5026.), Wydawca: NAS USA
    Status:
    Published
    DOI:
    10.1073/pnas.1807864116 - link to the publication
  3. Mating preferences can drive expansion or contraction of major histocompatibility complex gene family
    Authors:
    Bentkowski. P, Radwan, J.
    Academic press:
    Proc. R. Soc. B (rok: 2020, tom: 287, strony: 20192706), Wydawca: Royal Society
    Status:
    Published
    DOI:
    10.1098/rspb.2019.2706 - link to the publication
  4. Amplisas: A web server for multilocus genotyping using next-generation amplicon sequencing data
    Authors:
    Sebastian, A., Herdegen, M., Migalska, M., & Radwan, J.
    Academic press:
    Molecular Ecology Resources (rok: 2016, tom: 16, strony: 498-510), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/1755-0998.12453 - link to the publication
  5. Testing genotyping strategies for ultra-deep sequencing of a co-amplifying gene family: MHC class I in a passerine bird
    Authors:
    Biedrzycka, A., Sebastian, A., Migalska, M., Westerdahl, H., & Radwan, J.
    Academic press:
    Molecular Ecology Resources (rok: 2017, tom: 17, strony: 642-655.), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/1755-0998.12612 - link to the publication
  6. Profiling of the TCRβ repertoire in non-model species using high-throughput sequencing.
    Authors:
    Migalska, M., Sebastian, A., & Radwan, J.
    Academic press:
    Scientific Reports (rok: 2018, tom: 8, strony: Article number: 11613), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-018-30037-0 - link to the publication
  7. Evolution of major histocompatibility complex gene copy number
    Authors:
    Bentkowski, P., Radwan, J.
    Academic press:
    Plos Computational Biology (rok: 2019, tom: 15(5), strony: e1007015.), Wydawca: PLOS
    Status:
    Submitted
    DOI:
    10.1371/journal.pcbi.1007015 - link to the publication

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